DNA strand methylation and sister chromatid exchanges in mammalian cells in vitro

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 429, Issue 2, 1999, Pages 239-248

  Albanesi, Tiziana ^a   Polani, Stefania ^a   Cozzi, Renata ^b   Perticone, Paolo ^a  

^a CNR   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

Author keywords

CHO K1; Demethylation; DNA damage; DNA strand; Epigenetic damage; Mismatch repair; Replication fork; Sister chromatid exchanges

Indexed keywords

AZACITIDINE; ETHIONINE; HYDROGEN PEROXIDE; MITOMYCIN C; MUTAGENIC AGENT;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; CELL CYCLE; CELL DIVISION; CHO CELL; CONTROLLED STUDY; DEMETHYLATION; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA STRAND; HYPOTHESIS; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE; ULTRAVIOLET IRRADIATION;

ANIMALS; AZACITIDINE; BROMODEOXYURIDINE; CELL CYCLE; CHO CELLS; CRICETINAE; DNA DAMAGE; DNA METHYLATION; ETHIONINE; HYDROGEN PEROXIDE; MITOMYCIN; MUTAGENS; SISTER CHROMATID EXCHANGE; ULTRAVIOLET RAYS;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0032835203     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00112-8     Document Type: Article

References (41)

1. A.A. Sandberg, Sister Chromatid Exchange, Alan R. Liss, New York, 1982.
2. Perticone P., Linguardo M., Cozzi R., Corbo R.M., Polani S. Persistence of sister chromatid exchange by 9-β-D-arabinofuranosyladenine in Chinese hamster ovary cells cultivated in vitro. Mutagenesis. 8:1993;445-448.
3. Chambers J.C., Taylor J.H. Induction of sister chromatid exchanges by 5-fluorodeoxycitidine: correlation with DNA methylation. Chromosoma. 85:1982;603-609.
4. Tada-Aki H. Induction of chromosome decondensation, sister chromatid exchanges and endoreduplication by 5-azacytidine, an inhibitor of DNA methylation. Mutat. Res. 121:1983;47-52.
5. Ikushima T. SCE and DNA methylation. Basic Life Sci. 29(Pt. A):1984;161-172.
6. Lavia P., Ferraro M., Micheli A., Olivieri G. Effect of 5-azacytidine on the induction of chromatid aberrations and sister chromatid exchanges. Mutat. Res. 149:1985;463-467.
7. Shipley J., Sakai K., Tantravahi U., Fendrock B., Latt S.A. Correspondence between effects of 5-azacytidine on SCE formation, cell cycling and DNA methylation in Chinese hamster cells. Mutat. Res. 150:1985;333-345.
8. Bianchi N.O., Larramendy M., Bianchi M.S. The asymmetric methylation of CG palindromic dinucleotides increases sister-chromatid exchanges. Mutat. Res. 197:1988;151-156.
9. J.P. Jost, H.P. Saluz, DNA Methylation. Molecular Biology and Biological Significance, Birkhäuser Verlag, Basel, 1993.
10. 1 human lymphocytes under liquid-holding recovery conditions. Mutat. Res. 128:1984;153-159.
11. Perticone P., Cozzi R., Gustavino B. Sister chromatid exchanges induced by DNA demethylating agents persist through several cell cycles in mammalian cells. Carcinogenesis. 8(8):1987;1059-1063.
12. Perticone P., Palitti F., Cozzi R., D'Erme M., Bona R. Persistence of azacytidine-induced SCEs and genomic methylation in CHO cells in vitro. Mutat. Res. 245:1990;211-215.
13. Perticone P., Gensabella G., Cozzi R. Damage proneness induced by genomic DNA demethylation in mammalian cells cultivated in vitro. Mutagenesis. 12(4):1997;259-264.
14. Woodcock D.M., Crowther P.J., Hunter S.D., Cooper I.A. DNA sequences showing a delay in cytosine methylation after replication. Time course of methylation in synchronized mammalian cell populations and relationship to DNAse I sensitive domains. Biochem. Biophys. Acta. 741:1983;38-46.
15. Boehm T.L.J., Drahowsky D. Elevated transcriptional complexity and decrease in enzymatic DNA methylation in cells treated with L-ethionine. Cancer Res. 41:1981;4101-4106.
16. Santi D.W., Garrett C.E., Barr P.J. On the mechanism of inhibition of DNA-cytosine methyltransferase by cytosine analogs. Cell. 33:1983;9-10.
17. Santi D.V., Norment A., Garrett C.E. Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc. Natl. Acad. Sci. U.S.A. 81:1984;6993-6997.
18. Cox R., Irving C.C. Inhibition of DNA methylation by s-adenosylethyionine with the production of methyl-deficient DNA in degenerating rat liver. Cancer Res. 37:1977;222-225.
19. Boehm T.L.J., Drahowsky D. Effect of carcinogen ethionine on enzymatic methylation of DNA sequences with various degrees of repetitiveness. Eur. J. Cancer. 16:1979;1167-1173.
20. Ivett J.L., Tice R.R. Average generation time: a new method of analysis and quantitation of cellular proliferation kinetics. Environ. Mutagen. 4:1982;358.
21. L.G. Littlefield, Effects of DNA-damaging agents on SCE, in: Sister Chromatid Exchange, 1982, pp. 355-394.
22. Piñero J., Cortés F. Abnormally high incidence of SCE in three successive cell cycles in the CHO mutant EM) as detected by a three-way immunoperoxidase differential staining. Mutat. Res. 292:1993;205-211.
23. Ponzanelli I., Landi S., Barale R. Use of three-way differential staining and liquid holding for the assessment of individual repair capacity. Mutat. Res. 346:1995;93-97.
24. Ponzanelli I., Landi S., Bernacchi F., Barale F. The nature of high frequency sister chromatid exchange cells (HFCs). Mutagenesis. 12(5):1997;329-333.
25. Natarajan A.T., Czukas I., Van Zeeland A.A. Contribution of incorporated 5-bromodeoxyuridine in DNA to the frequencies of sister chromatid exchanges induced by inhibitors of poly-(ADP-ribose)-polymerase. Mutat. Res. 84:1981;125-132.
26. O'Neill J.P., Heartlein M.W., Preston R.J. Sister chromatid exchanges and gene mutation are induced by replication of 5-bromo- and 5-chloro-deoxyuridine substituted DNA. Mutat. Res. 109:1983;259-270.
27. Escalza P., Cortes F., Schvartzmann J.B. Induction of sister chromatid exchange (SCEs) by 5-fluorodeoxyuridine. The role of 5-bromodeoxyuridine incorporated into parental DNA. Mutat. Res. 151:1985;77-82.
28. Cortes F., Morgan W.F., Wolff S. Effects of esogenous thymidine on sister chromatid exchange frequency in Chinese hamster ovary cells with bromodeoxyuridine- and chlorodeoxyuridine-substituted chromosomes. Mutat. Res. 192:1987;277-282.
29. Fonatsch C., Schaadt M., Kirchner H., Diehl V. A possible correlation between the degree of karyotype aberrations and the rate of sister chromatid exchanges in lymphoma lines. Int. J. Cancer. 26(6):1980;749-756.
30. Knees-Matzen S., Roser M., Reimers U., Ehlert U., Weichenthal M., Breitbart E.W., Rudiger H.W. Increased UV-induced sister chromatid exchange in cultured fibroblasts of first degree relatives of melanoma patients. Cancer Genet. Cytogenet. 53(2):1991;265-270.
31. Miranda M., Ligas C., Amicarelli F., D'Alessandro E., Brisdelli F., Zarivi O., Poma A. Sister chromatid exchange (SCE) rates in human melanoma cells as an index of mutagenesis. Mutagenesis. 12(4):1997;233-236.
32. El-Hage S., Singh S.M. A 5-fold reduction in sister chromatid exchange following implantation of mouse embryos is not directly related to the expression of embryonic genes responsible for oxygen radical metabolism. Mutat. Res. 232(2):1990;217-226.
33. Vatolin S.Y., Okhapkina E.V., Matveeva N.M., Shilov A.G., Baiborodin S.I., Philimonenko V.V., Zhdanova N.S., Serov O.lL. Scheduled perturbation in DNA during in vitro differentiation of mouse embryo-derived cells. Mol. Reprod. Dev. 47(1):1997;1-10.
34. Brandeis M., Ariel M., Cedar H. Dynamics of DNA methylation during development. BioEssays. 15(11):1993;709-713.
35. Jost J.P., Jost Y.C. Transient DNA demethylation in differentiating mouse myoblasts correlates with higher activity of 5-methyldeoxycytidine excision repair. J. Biol. Chem. 269(13):1994;10040-10043.
36. Jost J.P., Jost Y.C. Mechanism of active DNA demethylation during embryonic development and cellular differentiation in vertebrates. Gene. 157(1-2):1995;265-266.
37. E.C. Friedberg, G.C. Walker, W. Siede (Eds.), Mismatch Repair, in: DNA Repair and Mutagenesis, ASM Press, 1995, pp. 367-405.
38. 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations and gene mutations: new insight gained from studies of genetically engineered mammalian cell lines. Environ. Mol. Mutagen. 22:1993;283-292.
39. Galloway S.M., Greenwood S.K., Hill R.B., Bradt C.I., Bean C.L. A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells. Mutat. Res. 346:1995;231-245.
40. Armstrong M.J., Galloway S.M. Mismatch repair provokes chromosome aberrations in hamster cells treated with methylating agents or 6-thyoguanine, but not with ethylating agents. Mutat. Res. 373:1997;167-187.
41. Patkin E.L., Kustova M.E., Perticone P. The influence of demethylating agents on preimplantation development of mice. Zygote. 6(4):1998;351-358.