Genomics: The implications for ethics and education

British Medical Bulletin

Volumn 55, Issue 2, 1999, Pages 429-445

  Thomas, Sandy M ^a  

^a UK Human Genetics Commission   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIOR; CONFIDENTIALITY; EMPLOYER; ETHICS; GENE MAPPING; GENETIC PREDISPOSITION; HEALTH CARE; HUMAN; INSURANCE; PRIORITY JOURNAL; REVIEW;

BIOMEDICAL AND BEHAVIORAL RESEARCH; GENETICS AND REPRODUCTION;

ETHICS, MEDICAL; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOME, HUMAN; HUMANS; PATIENT EDUCATION;

EID: 0032834508     PISSN: 00071420     EISSN: None     Source Type: Journal    
DOI: 10.1258/0007142991902358     Document Type: Review

References (61)

1. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
2. Ibid, page 3
3. Ibid, page 3
4. Human Genetic Advisory Commission. The Implications of Genetic Testing for Insurance. London: The Human Genetics Advisory Commission, 1997
5. Harper P. Practical Genetic Counselling, 4th edn. Oxford: Butterworth-Heinemann, 1998
6. Nuffield Council on Bioethics. Genetic Screening: ethical issues. London: Nuffield Council on Bioethics, 1993
7. Harper P, Clark A. Genetics, Society and Clinical Practice. Oxford: Bios Scientific, 1997
8. British Medical Association. Human Genetics: choice and responsibility. Oxford OUP, 1998
9. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998; 34
10. Michie S, Marteau T. Genetic counselling: some issues of theory and practice. In: Marteau T, Richards M. eds. The Troubled Helix. Cambridge: CUP, 1996
11. Craufurd D, Tyler A. Predictive testing for Huntingdon's disease: protocol of the UK Huntingdon's Prediction Consortium. J Med Genet 1992; 29: 915-8
12. Richards M. Annotation: genetic research, family life, and clinical practice. J Child Psychol Psychiatry 1998; 39: 291-305
13. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998; 38
14. Dudok de Wit A. To know or not to know: the psychological implications of presymtomatic DNA testing for autosomal dominant inheritable late onset disorders. Doctoral thesis, University of Utrecht, 1997
15. The Law Commission. Mental Incapacity. Law Commission No. 231. London: HMSO, 1995
16. Department of Health, Welsh Office. Code of Practice: Mental Health Act 1983. London: HMSO paragraph 15.8-15.24; 1993 Lord Chancellor's Department. Who decides? Making decisions on behalf of mentally incapacitated adults. Cm 3803, London: Lord Chancellor's Department, 1997
17. Department of Health, Welsh Office. Code of Practice: Mental Health Act 1983. London: HMSO paragraph 15.8-15.24; 1993 Lord Chancellor's Department. Who decides? Making decisions on behalf of mentally incapacitated adults. Cm 3803, London: Lord Chancellor's Department, 1997
18. Nuffield Council on Bioethics. Human Tissues: ethical and legal issues. London: Nuffield Council on Bioethics, 1995
19. After the decision of the House of Lords in Gillick v. West Norfolk and Wisbech Issues Health Area Authority 1985 3 ALL ER 402
20. Wertz D, Fanos K, Reilly P. Genetic testing for children and adolescents: who decides? JAMA 1994; 272: 878-81 Chappie A, May C, Campion P. Predictive and carrier testing of children: professional dilemmas for clinical geneticists. Eur J Genet Sociol 1996; 2: 28-38 McLean S. Genetic screening of children; the UK position. J Contemp Health Law Policy 1995; 20: 113-30 Michie A, Marteau T. Predictive genetic testing in children: the need for psychological research, Br J Health Psychol 1998; 1: 3-14 Clarke A. ed. Genetic Testing of Children. Oxford: Bios Scientific, 1998
21. Wertz D, Fanos K, Reilly P. Genetic testing for children and adolescents: who decides? JAMA 1994; 272: 878-81 Chappie A, May C, Campion P. Predictive and carrier testing of children: professional dilemmas for clinical geneticists. Eur J Genet Sociol 1996; 2: 28-38 McLean S. Genetic screening of children; the UK position. J Contemp Health Law Policy 1995; 20: 113-30 Michie A, Marteau T. Predictive genetic testing in children: the need for psychological research, Br J Health Psychol 1998; 1: 3-14 Clarke A. ed. Genetic Testing of Children. Oxford: Bios Scientific, 1998
22. Wertz D, Fanos K, Reilly P. Genetic testing for children and adolescents: who decides? JAMA 1994; 272: 878-81 Chappie A, May C, Campion P. Predictive and carrier testing of children: professional dilemmas for clinical geneticists. Eur J Genet Sociol 1996; 2: 28-38 McLean S. Genetic screening of children; the UK position. J Contemp Health Law Policy 1995; 20: 113-30 Michie A, Marteau T. Predictive genetic testing in children: the need for psychological research, Br J Health Psychol 1998; 1: 3-14 Clarke A. ed. Genetic Testing of Children. Oxford: Bios Scientific, 1998
23. Wertz D, Fanos K, Reilly P. Genetic testing for children and adolescents: who decides? JAMA 1994; 272: 878-81 Chappie A, May C, Campion P. Predictive and carrier testing of children: professional dilemmas for clinical geneticists. Eur J Genet Sociol 1996; 2: 28-38 McLean S. Genetic screening of children; the UK position. J Contemp Health Law Policy 1995; 20: 113-30 Michie A, Marteau T. Predictive genetic testing in children: the need for psychological research, Br J Health Psychol 1998; 1: 3-14 Clarke A. ed. Genetic Testing of Children. Oxford: Bios Scientific, 1998
24. Wertz D, Fanos K, Reilly P. Genetic testing for children and adolescents: who decides? JAMA 1994; 272: 878-81 Chappie A, May C, Campion P. Predictive and carrier testing of children: professional dilemmas for clinical geneticists. Eur J Genet Sociol 1996; 2: 28-38 McLean S. Genetic screening of children; the UK position. J Contemp Health Law Policy 1995; 20: 113-30 Michie A, Marteau T. Predictive genetic testing in children: the need for psychological research, Br J Health Psychol 1998; 1: 3-14 Clarke A. ed. Genetic Testing of Children. Oxford: Bios Scientific, 1998
25. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics. 1998; 42
26. Clark A. The Genetic Testing of Children: report of a working party of the Clinical Genetics Society. London: Clinical Genetics Society, 1994
27. Green J. Steatham H. Psychological aspects of prenatal screening and diagnosis. In: Marteau T, Richards M. eds. The Troubled Helix. Cambridge: CUP, 1996
28. See for example: Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
29. Ibid, page 51
30. American College of Medical Genetics/American Society of Human Genetics Working Group on ApoE and Alzheimer disease. Statement on usefulness of apolipoprotein E testing for Alzheimer disease, JAMA 1995; 274: 1627-9
31. Post S et al The clinical introduction of genetic testing for Alzheimer's disease, JAMA 1997; 277: 832-6
32. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
33. Ibid, page 25
34. Rutter M, Plomin R. Opportunities for psychiatry from genetic findings, Br J Psychiatry 1997; 171: 209-19
35. William J et al. European Multicentre Study of Schizophrenia (EMASS) Group. Lancet 1996; 347: 1294-6
36. Marteau T, Croyle R. Psychological responses to genetic testing. BMJ 1998; 316: 693-6
37. Rutter M, Plomin R. Opportunities for psychiatry from genetic findings. Br J Psychiatry 1997; 171: 209-19
38. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
39. Clarke A. The genetic dissection of multifactorial disease: the implications of susceptibility screening. In: Clarke A. ed. Genetics, Society and Clinical Practice. Oxford: Bios Scientific, 1997, 100
40. The voluntary code of practice for directing marketed tests in the UK has been drawn up by the Advisory Committee on Genetic Testing, a non-statutory Government advisory body
41. Association of British Insurers. Genetic Testing: ABI code of practice. London: Association of British Insurers, 1997
42. Human Genetics Advisory Commission. The Implications of Genetic Testing for Insurance. London: The Human Genetics Advisory Commission, 1997
43. Association of British Insurers (ABI). Genetics: Code of Practice. London: ABI, Press Release 17 December 1997
44. Nuffield Council on Bioethics. Genetic Screening: ethical issues. London: Nuffield Council on Bioethics, 1993; 64
45. House of Commons Select Committee on Science and Technology. Human Genetics: the science and its consequences. House of Commons 1994-95, volume 1, report and minutes of proceedings session 41-1, London: HMSO, 1995; paragraph 226
46. Holm S. Presentation to Conference on Genetics Information: acquisition, access and control. Preston: University of Central Lancashire, 5-6 December 1997
47. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
48. Ibid, page 19
49. Ibid, page 5
50. Knoppers BM et al. Control of DNA samples and information. Genomics 1998; 50: 385-401
51. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
52. Ibid
53. Ibid, page 70. The American Society of Human Genetics. DNA banking and DNA analysis: points to consider. Am J Hum Genet 1997; 8: 781
54. Ibid, page 70. The American Society of Human Genetics. DNA banking and DNA analysis: points to consider. Am J Hum Genet 1997; 8: 781
55. Ibid, page 71
56. Ibid, page 72
57. Kinmouth AL, Reinhard J, Bobrow M. The new genetics: implications for clinical services in Britain and the United States. BMJ 1998; 316: 767
58. Harper PS. Genetic testing for common diseases and health care provision. Lancet 1995; 346: 1645-6
59. Nuffield Council on Bioethics. Mental Disorders and Genetics: the ethical context. London: Nuffield Council on Bioethics, 1998
60. Kinmouth AL, Reinhard J, Bobrow M. The new genetics: implications for clinical services in Britain and the United States. BMJ 1998; 316: 767
61. Initiatives to encourage the public to familiarise themselves about genetics include the Gene Shop at Manchester Airport, citizen's juries, focus groups, consensus conferences and the work of charities such as the Genetic Interest Group in the UK