The effect of sympatholytics on uncontrolled hemorrhage

Critical Care Medicine

Volumn 27, Issue 9, 1999, Pages 1856-1861

  Rudé, Malcolm J ^a   Soucy, Dana M ^a   Hagedorn, Frederick ^a   Illner, Hana ^a   Shires, G Tom ^b  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

adrenergic antagonist; adrenergic antagonist; Female; Hemorrhage; Phenoxyberzamine; Propranolol; Rats; Shock; Sprague Dawley; Sympatholytics; Uncontrolled hemorrhage

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; PHENOXYBENZAMINE; PROPRANOLOL;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; CONTROLLED STUDY; FEMALE; HEMODYNAMICS; HYPOTENSION; MORTALITY; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; RAT; RESUSCITATION; SURVIVAL TIME;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FEMALE; HEMODYNAMIC PROCESSES; HEMORRHAGE; PHENOXYBENZAMINE; PROPRANOLOL; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SURVIVAL RATE; SYMPATHOLYTICS; TIME FACTORS;

EID: 0032834453     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199909000-00025     Document Type: Article

References (40)

1. 1. American College of Surgeons Committee on Trauma: Advanced Trauma Life Support Course Manual. Chicago, IL, American College of Surgeons, 1989
2. 2. Caroline NL: Emergency Care in the Streets. Second Edition. Boston, Little, Brown and Co, 1983
3. 3. Wiggers CJ: Physiology of Shock. New York, Commonwealth Publications, 1950
4. 4. McClelland RN, Shires GT, Baxter CR, et al: Balanced salt solution in the treatment of hemorrhagic shock. JAMA 1967; 199: 830-834
5. 5. Shires GT, Cunningham JN, Baker CRF, et al: Alterations in cellular membrane function during hemorrhagic shock in primates. Ann Surg 1972; 176:288-295
6. 6. Cunningham JN, Shires GT, Wagner Y: Cellular transport defects in hemorrhagic shock. Surgery 1971; 70:215-222
7. 7. Soucy DM, Sindlinger JF, Greene SP, et al: Isotonic saline resuscitation in uncontrolled hemorrhage under various anesthetic conditions. Ann Surg 1995; 222:87-93
8. 8. Sindlinger J, Soucy D, Greene S, et al: The effects of isotonic saline volume resuscitation in uncontrolled hemorrhage. Surg Gynecol Obstet 1993; 177:545-550
9. 9. Kowalenko T, Stern S, Dronen S, et al: Improved outcome with hypotensive resuscitation of uncontrolled hemorrhagic shock in a swine model. J Trauma 1992; 33:349-353
10. 10. Cannon WB, Fraser J, Cowell EM: The preventive treatment of wound shock. JAMA 1918; 70:618-621
11. 11. Gross D, Landau EH, Assalia A, et al: Is hypertonic saline resuscitation safe in "uncontrolled" hemorrhagic shock? J Trauma 1988; 28:751-756
12. 12. Krausz MM, Bar-Ziv M, Rabinovici R, et al: "Scoop and run" or stabilize hemorrhagic shock with normal saline or small-volume hypertonic saline? J Trauma 1992; 33:6-10
13. 13. Stern SA, Dronen SC, Birrer P, et al: Effect of blood pressure on hemorrhagic volume and survival in a near-fatal hemorrhage model incorporating a vascular injury. Ann Emerg Med 1993; 22:155-163
14. 14. Bruttig SP, O'Benar JD, Bickell WH, et al: Effects of immediate versus delayed fluid resuscitation on hemorrhage volume and mortality in anesthetized pigs. Circ Shock 1990; 31:70-71
15. 15. Bickell WH, Bruttig SP, Millnamow M A, et al: The detrimental effects of intravenous crystalloid after aortotomy in swine. Surgery 1991; 110:529-536
16. 16. Bickell WH, Matthew JW Jr, Pepe PE, et al: Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries. N Engl J Med 1994; 331: 1105-1109
17. 17. Bilynskyj MCV, Errington ML, Velasco IT, et al: Effect of hypertonic sodium chloride on uncontrolled hemorrhage in rats and its interaction with different anesthetic procedures. Circ Shock 1992; 36:68-73
18. 18. Soucy D, Sindlinger J, Greene S, et al: The effects of anesthesia on uncontrolled hemorrhage in rats. Crit Care Med 1994; 22:A218
19. 19. Farnebo L, Hallman H, Hamberger B, et al: Catecholamines and hemorrhagic shock in awake and anesthetized rats. Circ Shock 1979; 6:109-118
20. 20. Spoerel WE: Adrenergic blocking agents in shock. J Can Anaesth Soc 1958; 5:170-176
21. 21. Zierott G, Pappova E, Lundsgaard-Hansen P: Combined adrenergic blockade in experimental hemorrhagic hypotension. Pflugers Arch 1969; 310:1-15
22. 22. Parratt J: Neurohumoral agents their release in shock. In: Handbook of Shock and Trauma: Basic Sciences. Vol 1. Altura BM, Lefer AM, Schumer W (Eds). New York, Raven Press, 1983, pp 311-336
23. 23. Eckenhoff JE, Cooperman LH: The clinical application of phenoxybenzamine in shock and vasoconstrictive states. Surg Gynecol Obstet 1965; 121:483-490
24. 24. Halmagyi DF, Kennedy M, Varga D: Combined adrenergic receptor blockade and circulating catecholamines in hemorrhagic shock. Eur Surg Res 1971; 3:378-388
25. 25. Chien S: Role of the sympathetic nervous system in hemorrhage. Physiol Rev 1967; 47:214-289
26. 26. Berk JL: Use of vasoactive drugs in the treatment of shock. Surg Clin North Am 1975; 55:721-728
27. 27. Chien S, Simchon S: The sympathetic and central nervous systems in shock. In: Handbook of Shock and Trauma: Basic Sciences. Vol I. Altura BM, Lefer AM, Schumer W (Eds). New York, Raven Press, 1983, pp 149-166
28. 28. Nickerson M, Gourzis JT: Blockade of sympathetic vasoconstriction in the treatment of shock. J Trauma 1962; 2:399-411
29. 29. Soucy DM, Sindlinger JF, Greene SP, et al: Effects of anesthesia on a model of uncontrolled hemorrhage in rats. Crit Care Med 1995; 23:1528-1532
30. 30. Baez S, Srikantia SG, Burack B: Dibenzyline protection against shock and preservation of hepatic ferritin systems. Am J Physiol 1958; 192:175-180
31. 31. Remington JW, Hamilton WF, Boyd GH, et al: Role of vasoconstriction in the response of the dog to hemorrhage. Am J Physiol 1950; 161:116-124
32. 32. Schumer W: The microcirculatory and metabolic effects of dibenzyline in oligemic shock. Surg Gynecol Obstet 1966; 123: 787-791
33. 33. Wiggers HC, Goldberg H, Roemhild F, et al: Impending hemorrhagic shock and the course of events following administration of dibenamine. Circulation 1950; 2:179-185
34. 34. Halmagyi DF, Gillett DJ, Irving MH: Partial and "complete" adrenergic blockade in posthemorrhagic shock. J Appl Physiol 1967; 22:487-494
35. 35. Berk JL, Hagen JF, Beyer WH, et al: The treatment of hemorrhagic shock by beta adrenergic receptor blockade. Surg Gynecol Obstet 1967; 125:311-318
36. 36. Berk JL, Hagen JF, Maly G, et al: The treatment of shock with beta adrenergic blockade. Arch Surg 1972; 104:46-51
37. 37. Halmagyi DF: Combined adrenergic receptor blockade in experimental posthemorrhagic shock. Med J Aust 1971; 2:720-723
38. 38. Weiner N: Drugs that inhibit adrenergic nerves and block adrenergic receptors. In: The Pharmacologic Basis of Therapeutics. Seventh Edition. Gilman AC, Rall TW, Nies AS, Taylor P (Eds). New York, Pergamon Press, 1985, pp 181-214
39. 39. Weil M H, Shubin H, Carlson R: Treatment of circulatory shock-use of sympathomimetic and related vasoactive agents. JAMA 1975; 231:1280-1286
40. 40. Weiner N, Taylor P: Neurohumoral transmission: The automatic and somatic motor systems. In: The Pharmacologic Basis of Therapeutics. Seventh Edition. Gilman AG, Rall TW, Nies AS, Taylor P (Eds). New York, Pergamon Press, 1985, pp 66-99