The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 106, Issue 9, 1999, Pages 929-936

  Whitlow, B J ^a   Chatzipapas, I K ^a   Lazanakis, M L ^a   Kadir, R A ^a   Economides, D L ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHROMOSOME ABERRATION; CLINICAL TRIAL; ECHOGRAPHY; EMBRYO; FEMALE; FETUS DISEASE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HEALTH CARE COST; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SECOND TRIMESTER PREGNANCY; TRISOMY 21;

CHROMOSOME ABERRATIONS; COSTS AND COST ANALYSIS; CROSS-SECTIONAL STUDIES; FEMALE; FETUS; HUMANS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; ULTRASONOGRAPHY, PRENATAL;

EID: 0032834378     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.1999.tb08432.x     Document Type: Article

References (24)

1. Economides DL, Whitlow BJ, Kadir R, Lazanakis ML. Verdin S. First trimester sonographic detection of chromosomal abnormalities in an unselected population. Br J Obstet Gynaecol 1998; 105: 58-62.
2. Grimes PA, Cates W. Complications from legally induced abortion: A review. Obstet Gynecol Sum, 1979; 34: 177-191.
3. White-van Mourik M, Connor I, Ferguson-Smith M. The psychological sequelae of a second trimester termination of pregnancy for a fetal abnormality. Prenat Diagn 1992; 12: 189-204.
4. Royal College of Obstetricians and Gynaecologists Working Party. Routine ultrasound examination in pregnancy. London : Royal College of Obstetricians and Gynaecologists, 1984: 23.
5. Hernadi L, Torocsik M. Screening for fetal anomalies in the 12th week of pregnancy by trans-vaginal sonography on a non-selected population Prenat Diagn, 1997; 17: 753-759.
6. Economides DL, Braithwaite JM. First trimester ultrasonographic diagnosis of fetal abnormalities in a low risk population. Br J Obstet Gynaecol 1998; 105: 53-57.
7. Braithwaite JM, Armstrong MA, Economides DL. The assessment of fetal anatomy at 12-13 weeks using transabdominal and transvaginal sonography. Br J Obstet Gynecol 1996; 103: 82-85.
8. Ville Y, Lalondrelle C, Doumere S, et al. First trimester diagnosis of nuchal anomalies: significance and fetal outcome. Ultrasound Obstet Gynecol 1992; 2: 314-316.
9. Sebire NJ, Noble PL, Thorpe-Beeston JG, Snijders RJM, Nicolaides KH. Presence of the ‘lemon’ sign at the 10-14 week scan. Ultrasound Obstet Gynecol 1997; 10: 403-405.
10. Sharland GK, Allan LD. Screening for congenital heart disease prenatally. Results of a 2.5 year study in the south-east Thames region. Br J Obstet Gynecol 1992; 99: 220-225.
11. Meizner I, Bamhard Y. Achondrogenesis type I diagnosed by transvaginal ultrasonography at 13 weeks' gestation. Am J Obstet Gynecol 1995; 173: 1620-1622.
12. Blaas HG, Eik-Ness SH, Kiserud T, Hellevik LR. Early development of the forbrain and midbrain: A longitudinal study from 7 to 12 weeks of gestation. Ultrasound Obstet Gynecol 1994; 4: 183-192.
13. Chatzipapas IK, Whitlow BJ, Economides DL. The diagnosis of anencephaly in early pregnancy: the ‘Mickey-Mouse’ sign. Ultrasound Obstet Gynecol 1999; 13: 196-200.
14. Snijders RIM, Brizot ML, Faria M, Nicolaides KH. Fetal exomphalos at 11-14 weeks of gestation. J Ultrasound Med 1995; 14: 569-574.
15. Taipale P, Hiilesmaa V, Salonen R, Ylostalo P. Increased nuchal translucency as a marker for fetal chromosomal defects. N Engl J Med 1997; 337: 1654-1658.
16. BJ Whitlow, ML Lazanakis, RA Kadir, I Chatzipapas, DL Economides. The significance of choroid plexus cysts, echogenic heart foci and renal pyelectasis in the first trimester. Ultrasound Obstet Gynecol 1998; 12: 385-390.
17. Wald NJ, George L, Smith D, Densem JW, Petterson K. Serum screening for Down's syndrome between 8 and 14 weeks of pregnancy. Br J Obstet Gynaecol 1996; 103: 407-412.
18. Sepuldeva W, Sebire NJ, Hughes K, Odiho A, Nicolaides KH. The lambda sign at 10-14 weeks as a predictor for chorionicity in twin pregnancies. Ultrasound Obstet Gynecol 1996; 7: 421-423.
19. Blanch G, Quenby S, Ballantyne ES, Gosden CM, Neilson JP. Embryonic abnormalities at medical termination of pregnancy with mifepristone and misoprostol during first trimester: observational study. BMJ 1998; 316: 1712-1713.
20. Spitz IM, Bardin CW, Benton L, Robbins A. Early pregnancy termination with mifepristone and misoprostol in the United States. New Engl J Med 1998; 338: 1241-1247.
21. Chitty LS, Hunt GH, Moore J, Lobb MO. Effectiveness of routine ultrasonography in detecting fetal structural abnormalities in a low risk population. BMJ 1991; 303: 1165-1169.
22. Luck CA. Value of routine ultrasound scanning at 19 weeks: A four year study of 8849 deliveries. BMJ 1992; 304: 1474-1478.
23. The Radius Study Group. A randomised trial of prenatal ultrasound screening in a low risk population: impact on perinatal outcome. New Engl J Med 1993; 329: 821-827.
24. Goldstein H. One year of health and social services for adolescents with Down's syndrome. A calculation of costs in a representative area of Denmark. Soc Psych Psychiatric Epidemiol 1989; 24: 30-34.