Disparity of cell swelling and rapid neuronal death by excitotoxic insults in rat hippocampal slice cultures

Neuroscience Letters

Volumn 274, Issue 2, 1999, Pages 135-138

  Sakaguchi, Takuya ^a   Kuno, Motoy ^a   Kawasaki, Kazuo ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

Ca2+; Cell swelling; Cl ; Hypotonic insult; N Methyl D aspartate; Neuronal death; Propidium iodide

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL SWELLING; CONTROLLED STUDY; DOSE RESPONSE; HIPPOCAMPUS; IN VITRO STUDY; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CELL DEATH; CELL SIZE; CHLORIDES; COLORING AGENTS; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; HYPOTONIC SOLUTIONS; N-METHYLASPARTATE; NEUROTOXINS; ORGAN CULTURE TECHNIQUES; PROPIDIUM; PYRAMIDAL CELLS; RATS;

EID: 0032834346     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00702-8     Document Type: Article

References (19)

1. - and inhibitory transmitters. Mol. Pharmacol. 53:1998;564-572.
2. Choi D.W. Ionic dependence of glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;369-379.
3. Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
4. Dessi F., Charriaut-Mariangue C., Ben-Ari Y. Glutamate-induced neuronal death in cerebellar culture is mediated by two distinct components. Brain Res. 650:1994;49-55.
5. Higashijima T., Ferguson K.M., Sternweis P.C. Regulation of hormone-sensitive GTP-dependent regulatory proteins by chloride. J. Biol. Chem. 262:1987;3597-3602.
6. - concentrations depress G-protein-modulated ionic conductance. J. Neurosci. 17:1997;6133-6141.
7. Michaels R., Rothman S.M. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J. Neurosci. 10:1990;283-292.
8. + channel in the cardiac atrial cell membrane. J. Gen. Physiol. 99:1992;665-682.
9. Olney J.W. Inciting excitotoxic cytocide among central neurons. Adv. Exp. Med. Biol. 203:1986;631-645.
10. Olney J.W., Price M.T., Samson L., Labruyere J. The role of specific ions in glutamate neurotoxicity. Neurosci. Lett. 65:1986;65-71.
11. Polischuk T.M., Javis C.R., Andrew R.D. Intrinsic optical denoting neuronal damage in response to acute excitotoxic insult by domoic acid in the hippocampal slice. Neurobiol. Dis. 4:1998;423-437.
12. Regan R.F., Choi D.W. Glutamate neurotoxicity in spinal cord cell culture. Neuroscience. 43:1991;585-591.
13. Rothman S.M. The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J. Neurosci. 5:1985;1483-1489.
14. Rothman S.M. Excitotoxins: possible mechanisms of action. Ann. N.Y. Acad. Sci. 648:1992;133-139.
15. Rothman S.M., Olney J.W. Excitotoxicity and the NMDA receptor. Trends Neurosci. 10:1987;299-302.
16. Sakaguchi T., Kuno M., Kawasaki K. Protection of excitotoxic neuronal death by gluconate through blockade of N-methyl-D-aspartate receptors. Neuroscience. 92:1999;677-684.
17. Sakaguchi T., Okada M., Kuno M., Kawasaki K. Dual mode of N-methyl-D-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties. Neuroscience. 76:1997;411-423.
18. Tymianski M., Charlton M.P., Carlen P.L., Tator C.H. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J. Neurosci. 13:1993;2085-2104.
19. Vornov J.J., Tasker R.C., Coyle J.T. Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures. Expl. Neurol. 114:1991;11-22.