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Volumn 24, Issue 2, 1999, Pages 121-126

Enantiomer-enantiomer interaction of a calcium channel antagonist, benidipine hydrochloride, during liver metabolism in the rat

Author keywords

Benidipine hydrochloride; Calcium channel antagonist; Enantiomer enantiomer interaction; Liver metabolism; Rat

Indexed keywords

BENIDIPINE; CALCIUM ANTAGONIST;

EID: 0032834138     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190356     Document Type: Article
Times cited : (9)

References (13)
  • 1
    • 0023686042 scopus 로고
    • Synthesis and pharmacological activity of stereoisomers of 1,4-dihydro-2,6-dimethyl-4(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl-1-(phenyl methyl)-3-piperidinyl ester
    • Muto K., Kuroda T., Kawato H., Karasawa A., Kubo K., Nakamizo N. (1988) : Synthesis and pharmacological activity of stereoisomers of 1,4-dihydro-2,6-dimethyl-4(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl-1-(phenyl methyl)-3-piperidinyl ester. Artzeimitellforschung., 38: 1662-1665.
    • (1988) Artzeimitellforschung. , vol.38 , pp. 1662-1665
    • Muto, K.1    Kuroda, T.2    Kawato, H.3    Karasawa, A.4    Kubo, K.5    Nakamizo, N.6
  • 2
    • 0023761772 scopus 로고
    • Receptor binding properties of the new calcium antagonist benidipine hydrochloride
    • Ishii A., Nishida K., Oka T., Nakamizo N. (1988) : Receptor binding properties of the new calcium antagonist benidipine hydrochloride. Artzeimitellforschung., 38: 1677-1680.
    • (1988) Artzeimitellforschung. , vol.38 , pp. 1677-1680
    • Ishii, A.1    Nishida, K.2    Oka, T.3    Nakamizo, N.4
  • 3
    • 0027523333 scopus 로고
    • Nonchiral, homochiral and composite chiral drugs
    • Ariëns E.J. (1993) : Nonchiral, homochiral and composite chiral drugs. Trends Pharmacol. Sci., 14: 68-75.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 68-75
    • Ariëns, E.J.1
  • 4
    • 0023796656 scopus 로고
    • Gas chromatographic method for the quantification of the new calcium antagonist benidipine hydrochloride in plasma using electron capture detection
    • Kobayashi H., Kobayashi S., Inoue A., Oka T., Nakamizo N. (1988) : Gas Chromatographic method for the quantification of the new calcium antagonist benidipine hydrochloride in plasma using electron capture detection. Artzeimitellforschung., 38: 1730-1733.
    • (1988) Artzeimitellforschung. , vol.38 , pp. 1730-1733
    • Kobayashi, H.1    Kobayashi, S.2    Inoue, A.3    Oka, T.4    Nakamizo, N.5
  • 5
    • 0022490237 scopus 로고
    • Drug ligand binding of pyridine alkanamide to microsomal cytochrome P-450
    • Repond C., Bulgheroni A., Meyer U.A., Mayer J.M. Testa B. (1986) : Drug ligand binding of pyridine alkanamide to microsomal cytochrome P-450. Biochem. Pharmacol., 35: 2233-2240.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 2233-2240
    • Repond, C.1    Bulgheroni, A.2    Meyer, U.A.3    Mayer, J.M.4    Testa, B.5
  • 7
    • 0023768445 scopus 로고
    • Identification of benidipine hydrochloride metabolites in rats and dogs
    • Kobayashi H., Okumura S., Kosaka Y. et al. (1988) : Identification of benidipine hydrochloride metabolites in rats and dogs. Artzeimitellforschung., 38: 1753-1756.
    • (1988) Artzeimitellforschung. , vol.38 , pp. 1753-1756
    • Kobayashi, H.1    Okumura, S.2    Kosaka, Y.3
  • 8
    • 0024602884 scopus 로고
    • Stereoselective disposition of nilvadipine a new dihydropyridine calcium antagonist, in the rat and dog
    • Tokuma Y., Fujiwara T., Niwa T., Hashimoto T., Noguchi H. (1989) : Stereoselective disposition of nilvadipine a new dihydropyridine calcium antagonist, in the rat and dog. Res. Commun. Chem. Pathol. Pharmacol., 63: 249-262.
    • (1989) Res. Commun. Chem. Pathol. Pharmacol. , vol.63 , pp. 249-262
    • Tokuma, Y.1    Fujiwara, T.2    Niwa, T.3    Hashimoto, T.4    Noguchi, H.5
  • 9
    • 0017335453 scopus 로고
    • Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance
    • Rane A., Wilkinson G.R., Shand D.G. (1977) : Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance. J. Pharmacol. Exp. Ther., 200: 420-424.
    • (1977) J. Pharmacol. Exp. Ther. , vol.200 , pp. 420-424
    • Rane, A.1    Wilkinson, G.R.2    Shand, D.G.3
  • 10
    • 0017603437 scopus 로고
    • Hepatic clearance of drugs: I. Theoretical considerations of a 'well-stirred' model and a 'parallel tube' model. Influence of hepatic blood flow, plasma and blood cell binding and the hepatocellular enzymatic activity on hepatic drug clearance
    • Pang K.S., Rowland M. (1977) : Hepatic clearance of drugs: I. Theoretical considerations of a 'well-stirred' model and a 'parallel tube' model. Influence of hepatic blood flow, plasma and blood cell binding and the hepatocellular enzymatic activity on hepatic drug clearance. J. Pharmacokinet. Biopharm., 5: 626-653.
    • (1977) J. Pharmacokinet. Biopharm. , vol.5 , pp. 626-653
    • Pang, K.S.1    Rowland, M.2
  • 11
    • 0344894659 scopus 로고
    • Pharmacokinetic study of benidipine hydrochloride in rats, dogs and monkeys
    • Kobayashi H., Kobayashi S., Inoue A., Hirata T. (1990) : Pharmacokinetic study of benidipine hydrochloride in rats, dogs and monkeys. Xenobiot. Metabol. Dispos., 5: 111-119.
    • (1990) Xenobiot. Metabol. Dispos. , vol.5 , pp. 111-119
    • Kobayashi, H.1    Kobayashi, S.2    Inoue, A.3    Hirata, T.4
  • 13
    • 0017103327 scopus 로고
    • Effect of 1-propoxyphene on plasma levels and analgesic activity of d-propoxyphene in the rat
    • Murphy P., Nickander R.C., Bellamy G.M., Kurtz. W.L. (1976): Effect of 1-propoxyphene on plasma levels and analgesic activity of d-propoxyphene in the rat. J. Pharmacol. Exp. Ther., 199:415-422.
    • (1976) J. Pharmacol. Exp. Ther. , vol.199 , pp. 415-422
    • Murphy, P.1    Nickander, R.C.2    Bellamy, G.M.3    Kurtz, W.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.