-
1
-
-
0019809960
-
Increased biolectric potential difference across respiratory epithelia in cystic fibrosis
-
Knowles MR, Gatzy JT, Boucher RC. Increased biolectric potential difference across respiratory epithelia in cystic fibrosis. N Engl J Med 1981; 305 (25): 1489-1495.
-
(1981)
N Engl J Med
, vol.305
, Issue.25
, pp. 1489-1495
-
-
Knowles, M.R.1
Gatzy, J.T.2
Boucher, R.C.3
-
2
-
-
0022973473
-
Na transport in cystic fibrosis respiratory epithelia: Abnormal basal rate and response to adenylate cyclase activation
-
Boucher RC, Stutts MJ, Knowles MR. Na transport in cystic fibrosis respiratory epithelia: abnormal basal rate and response to adenylate cyclase activation. J Clin Invest 1986; 78: 1245-1252.
-
(1986)
J Clin Invest
, vol.78
, pp. 1245-1252
-
-
Boucher, R.C.1
Stutts, M.J.2
Knowles, M.R.3
-
3
-
-
0023789980
-
Evidence for reduced Cl and increased Na permeability in cystic fibrosis human primary cell cultures
-
Boucher RC, Cotton CU, Gatzy JT. Evidence for reduced Cl and increased Na permeability in cystic fibrosis human primary cell cultures. J Physiol 1988; 405: 77-103.
-
(1988)
J Physiol
, vol.405
, pp. 77-103
-
-
Boucher, R.C.1
Cotton, C.U.2
Gatzy, J.T.3
-
4
-
-
0019490443
-
Measurements of nasal transepithelial electric potential differences in normal human subjects in vivo
-
Knowles MR, Carson JL, Collier AM, Gatzy JT, Boucher RC. Measurements of nasal transepithelial electric potential differences in normal human subjects in vivo. Am Rev Respir Dis 1981; 124: 484-490.
-
(1981)
Am Rev Respir Dis
, vol.124
, pp. 484-490
-
-
Knowles, M.R.1
Carson, J.L.2
Collier, A.M.3
Gatzy, J.T.4
Boucher, R.C.5
-
5
-
-
0025609981
-
Nasal potential difference: A clinical diagnostic test for cystic fibrosis
-
Alton EWFW, Currie D, Logan Sinclair R, Warner J, Hodson ME, Geddes DM. Nasal potential difference: a clinical diagnostic test for cystic fibrosis. Eur Respir J 1990; 3: 922-926.
-
(1990)
Eur Respir J
, vol.3
, pp. 922-926
-
-
Alton, E.W.F.W.1
Currie, D.2
Logan Sinclair, R.3
Warner, J.4
Hodson, M.E.5
Geddes, D.M.6
-
6
-
-
0028020058
-
Protocols for in vivo measurement of the ion transport defects in cystic fibrosis nasal epithelium
-
Middleton PG, Geddes DM, Alton EWFW. Protocols for in vivo measurement of the ion transport defects in cystic fibrosis nasal epithelium. Eur Respir J 1994; 7: 2050-2056.
-
(1994)
Eur Respir J
, vol.7
, pp. 2050-2056
-
-
Middleton, P.G.1
Geddes, D.M.2
Alton, E.W.F.W.3
-
7
-
-
0029122736
-
Effect of oral digoxin, topical oubain and salbutamol on trans-epithelial nasal potential difference in patients with cystic fibrosis
-
Peckham DG, Conn A, Chotai C, Lewis S, Knox AJ. Effect of oral digoxin, topical oubain and salbutamol on trans-epithelial nasal potential difference in patients with cystic fibrosis. Clin Science 1995; 89: 277-284.
-
(1995)
Clin Science
, vol.89
, pp. 277-284
-
-
Peckham, D.G.1
Conn, A.2
Chotai, C.3
Lewis, S.4
Knox, A.J.5
-
8
-
-
0344040199
-
An overview of the structure - Activity relations in the amiloride series
-
Cragoe EJ, Kleyman T, Simchowitz L, eds. New York VCH
-
Simchowitz L, Kleyman TR, Cragoe EJ. An overview of the structure - activity relations in the amiloride series. In: Cragoe EJ, Kleyman T, Simchowitz L, eds. Amiloride and its analogs - Unique cation transport inhibitors, New York VCH; 1992: 9-24.
-
(1992)
Amiloride and Its Analogs - Unique Cation Transport Inhibitors
, pp. 9-24
-
-
Simchowitz, L.1
Kleyman, T.R.2
Cragoe, E.J.3
-
9
-
-
0342970383
-
Amiloride-sensitive sodium channels
-
Cragoe EJ, Kleyman TR, Simcchowitz L, eds. New York, VCH
-
Young S, Benos O, Benos DJ. Amiloride-Sensitive Sodium Channels. In: Cragoe EJ, Kleyman TR, Simcchowitz L, eds. Amiloride and its Analogs. Unique cation transport inhibitors, New York, VCH, 1992; 41-56.
-
(1992)
Amiloride and Its Analogs. Unique Cation Transport Inhibitors
, pp. 41-56
-
-
Young, S.1
Benos, O.2
Benos, D.J.3
-
10
-
-
0028787073
-
Nebulised amiloride in respiratory exacerbations of cystic fibrosis: A randomised controlled trial
-
Bowler IM, Kelman B, Worthington D, et al. Nebulised amiloride in respiratory exacerbations of cystic fibrosis: a randomised controlled trial. Arch Dis Child 1995; 73: 427-430.
-
(1995)
Arch Dis Child
, vol.73
, pp. 427-430
-
-
Bowler, I.M.1
Kelman, B.2
Worthington, D.3
-
11
-
-
0025236867
-
A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis
-
Knowles MR, Church NL, Waltner WE, Yankakas JR, Gilligan P. A Pilot Study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis. N Engl J Med 1990; 322: 1189-1194.
-
(1990)
N Engl J Med
, vol.322
, pp. 1189-1194
-
-
Knowles, M.R.1
Church, N.L.2
Waltner, W.E.3
Yankakas, J.R.4
Gilligan, P.5
-
12
-
-
0027486593
-
No added benefit from nebulized amiloride in patients with cystic fibrosis
-
Graham A, Hasani A, Alton EWFW, et al. No added benefit from nebulized amiloride in patients with cystic fibrosis. Eur Respir J 1993; 6: 1243-1248.
-
(1993)
Eur Respir J
, vol.6
, pp. 1243-1248
-
-
Graham, A.1
Hasani, A.2
Alton, E.W.F.W.3
-
13
-
-
0022996487
-
Deposition, clearance and effects of aerosolized amiloride in sheep airways
-
Mentz WM, Brown JB, Friedman M, Stutts MJ, Gatzy JT, Boucher RC. Deposition, clearance and effects of aerosolized amiloride in sheep airways. Am Rev Respir Dis 1986; 134: 938-943.
-
(1986)
Am Rev Respir Dis
, vol.134
, pp. 938-943
-
-
Mentz, W.M.1
Brown, J.B.2
Friedman, M.3
Stutts, M.J.4
Gatzy, J.T.5
Boucher, R.C.6
-
14
-
-
0027216541
-
Effect of amiloride and saline on nasal mucociliary clearance and potential difference in cystic fibrosis and normal subjects
-
Middleton PG, Geddes DM, Alton EWFW. Effect of amiloride and saline on nasal mucociliary clearance and potential difference in cystic fibrosis and normal subjects. Thorax 1993; 48: 812-816.
-
(1993)
Thorax
, vol.48
, pp. 812-816
-
-
Middleton, P.G.1
Geddes, D.M.2
Alton, E.W.F.W.3
-
15
-
-
0025274624
-
Acute and long-term amiloride inhalation in cystic fibrosis lung disease
-
App EM, King M, Helfesrieder R, Kohler D, Matthys H. Acute and long-term amiloride inhalation in cystic fibrosis lung disease. Am Rev Respir Dis 1990; 141: 605-612.
-
(1990)
Am Rev Respir Dis
, vol.141
, pp. 605-612
-
-
App, E.M.1
King, M.2
Helfesrieder, R.3
Kohler, D.4
Matthys, H.5
-
16
-
-
0000930452
-
Amiloride in cystic fibrosis: Safety, pharmacokinetics, and efficacy in the treatment of pulmonary disease
-
Cragoe EJ, Kleyman TR, Simchowitz L, eds. New York, VCH
-
Knowles MR, Church NL, Waltner WE, Gatzy JT, Boucher RC. Amiloride in cystic fibrosis: safety, pharmacokinetics, and efficacy in the treatment of pulmonary disease. In: Cragoe EJ, Kleyman TR, Simchowitz L, eds. Amiloride and its Analogs - Unique Cation Transport Inhibitors. New York, VCH, 1992; 301-316.
-
(1992)
Amiloride and Its Analogs - Unique Cation Transport Inhibitors
, pp. 301-316
-
-
Knowles, M.R.1
Church, N.L.2
Waltner, W.E.3
Gatzy, J.T.4
Boucher, R.C.5
-
17
-
-
0029584796
-
Effects of benzamil on human cystic fibrosis airway epithelium
-
Blank U, Clauss W, Weber WM. Effects of benzamil on human cystic fibrosis airway epithelium. Cell Physiol Biochem 1995; 5: 385-390.
-
(1995)
Cell Physiol Biochem
, vol.5
, pp. 385-390
-
-
Blank, U.1
Clauss, W.2
Weber, W.M.3
-
18
-
-
0031862236
-
Effects of topically delivered benzamil and amiloride on nasal potential difference in cystic fibrosis
-
Hodmann T, Stutts MT, Ziersch A, et al. Effects of topically delivered benzamil and amiloride on nasal potential difference in cystic fibrosis. Am J Respir Crit Care Med 1998; 157: 1844-1849.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1844-1849
-
-
Hodmann, T.1
Stutts, M.T.2
Ziersch, A.3
-
19
-
-
0028230613
-
Nasal application of cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth
-
Middleton PG, Caplen NJ, Gao X, et al. Nasal application of cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth. Eur Respir J 1994; 7: 442-445.
-
(1994)
Eur Respir J
, vol.7
, pp. 442-445
-
-
Middleton, P.G.1
Caplen, N.J.2
Gao, X.3
-
20
-
-
0004296160
-
Deposition, pharmacokinetics and toxicity of amiloride aerosol in normal and cystic fibrosis subjects
-
Waltner WE, Church NL, Gatzy JT, Boucher RC, Knowles MR. Deposition, pharmacokinetics and toxicity of amiloride aerosol in normal and cystic fibrosis subjects. Am Rev Respir Dis 1987; 135: A288.
-
(1987)
Am Rev Respir Dis
, vol.135
-
-
Waltner, W.E.1
Church, N.L.2
Gatzy, J.T.3
Boucher, R.C.4
Knowles, M.R.5
-
21
-
-
0344471348
-
Dexamethasone increases sodium transport in human nasal epithelium in vivo
-
Hoffman T, Boy CE, Robinson JM, Homely V, Butcher RC, Knolls MR. Dexamethasone increases sodium transport in human nasal epithelium in vivo. Pediatr Pulmonol 1997; 14: 234.
-
(1997)
Pediatr Pulmonol
, vol.14
, pp. 234
-
-
Hoffman, T.1
Boy, C.E.2
Robinson, J.M.3
Homely, V.4
Butcher, R.C.5
Knolls, M.R.6
-
22
-
-
0029100239
-
A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
-
Knowles MR, Hohneker KW, Zhou Z, et al. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N Engl J Med 1995; 333: 823-831.
-
(1995)
N Engl J Med
, vol.333
, pp. 823-831
-
-
Knowles, M.R.1
Hohneker, K.W.2
Zhou, Z.3
-
23
-
-
0028913411
-
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Caplen NJ, Alton EWFW, Middleton PG, et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med 1995; 1: 39-46.
-
(1995)
Nature Med
, vol.1
, pp. 39-46
-
-
Caplen, N.J.1
Alton, E.W.F.W.2
Middleton, P.G.3
-
24
-
-
0025874599
-
Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis
-
Knowles MR, Clarke LL, Boucher RC. Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis. N Engl J Med 1991; 325: 533-538.
-
(1991)
N Engl J Med
, vol.325
, pp. 533-538
-
-
Knowles, M.R.1
Clarke, L.L.2
Boucher, R.C.3
-
25
-
-
0026591559
-
Extracellular ATP and UTP induce chloride secretion in nasal epithelia of cystic fibrosis patients and normal subjects in vivo
-
Knowles MR, Clarke LL, Boucher RC. Extracellular ATP and UTP induce chloride secretion in nasal epithelia of cystic fibrosis patients and normal subjects in vivo. Chest 1992; 101 (3): 60S-63S.
-
(1992)
Chest
, vol.101
, Issue.3
-
-
Knowles, M.R.1
Clarke, L.L.2
Boucher, R.C.3
-
26
-
-
0026611093
-
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells
-
Eidelman O, Guay-Broder C, Van Galen PJM, et al. A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells. Pro Natl Acad Sci 1991; 89: 5562-5566.
-
(1991)
Pro Natl Acad Sci
, vol.89
, pp. 5562-5566
-
-
Eidelman, O.1
Guay-Broder, C.2
Van Galen, P.J.M.3
-
27
-
-
0031889082
-
A pilot clinical trial of oral sodium 4 phenylbutyrate (Buphenyl) in delta F508 -homozygous cystic fibrosis patients
-
Rubenstein RC, Zeitlin PL. A pilot clinical trial of oral sodium 4 Phenylbutyrate (Buphenyl) in delta F508 -Homozygous cystic fibrosis patients. Am J Respir Crit Care Med 1998; 157: 484-490.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 484-490
-
-
Rubenstein, R.C.1
Zeitlin, P.L.2
-
28
-
-
0028944377
-
Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression
-
Cheng SH, Fang SL, Zabner J, et al. Functional activation of the cystic fibrosis trafficking mutant Delta F508-CFTR by overexpression. Am J Physiol 1995; 268: L615-L624.
-
(1995)
Am J Physiol
, vol.268
-
-
Cheng, S.H.1
Fang, S.L.2
Zabner, J.3
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