Splenectomy during partial remission in thrombotic thrombocytopenic purpura with prolonged plasma exchange dependency

American Journal of Hematology

Volumn 62, Issue 1, 1999, Pages 56-57

  Mant, Michael J ^a   Turner, A Robert ^a   Ritchie, D Bruce C ^a   Larratt, Loree M ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Hemolytic uremic syndrome; Mitomycin C; Splenectomy; Thrombotic microangiopathy; Thrombotic thrombocytopenic purpura

Indexed keywords

FRESH FROZEN PLASMA; MITOMYCIN C;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; HUMAN; PLASMAPHERESIS; PRIORITY JOURNAL; REMISSION; SPLENECTOMY; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT OUTCOME;

ADRENAL CORTEX HORMONES; ANTINEOPLASTIC AGENTS; ASPIRIN; COMBINED MODALITY THERAPY; ERYTHROCYTE TRANSFUSION; HUMANS; MITOMYCIN; PLASMA EXCHANGE; PLATELET AGGREGATION INHIBITORS; PLATELET COUNT; PURPURA, THROMBOTIC THROMBOCYTOPENIC; REMISSION INDUCTION; SPLENECTOMY; TREATMENT OUTCOME;

EID: 0032833146     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8652(199909)62:1<56::AID-AJH10>3.0.CO;2-5     Document Type: Article

References (8)

1. Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC, Spasoff RA, and the Canadian Apheresis Study Group. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. N Engl J Med 1991;325:393-397.
2. Hayward CP, Sutton DM, Carter WH Jr, Campbell ED, Scott JG, Francombe WH, Shumak KH, Baker MA: Treatment outcomes in patients with adult thrombocytopenic purpura-hemolytic uraemic syndrome. Arch Int Med 1994;154:982-987.
3. George JN, El-Harake M: Thrombocytopenia due to enhanced platelet destruction by nonimmunologic mechanisms. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, editors. Williams hematology, 5th. ed. New York: McGraw-Hill; 1995. p 1290-1355.
4. Bell WR: Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome relapse: frequency, pathogenesis, and meaning. Sem Hematol 1997;34:134.
5. Onundarson PT, Rowe JM, Heal JM, Francis CW: Response to plasma exchange and splenectomy in thrombotic thrombocytopenic purpura. A 10-year experience at a single institution. Arch Int Med 1992;152: 791-796.
6. Thompson CE, Damon LE, Ries CA, Linker CA: Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic. Blood 8:1890-1895, 1992.
7. Winslow GA, Nelson EW: Thrombotic thrombocytopenic purpura; Indications for and results of splenectomy. Am J Surg 1995;170:558-563.
8. Crowther MA, Heddle N, Hayward CPM, Warkentin T, Kelton JG: Splenectomy done during hematologic remission to prevent relapse in patients with thrombotic thrombocytopenic purpura. Ann Int Med 1996;125:294-296.