Bcl-2 and Bax regulation of apoptosis in germ cells during prenatal oogenesis in the mouse embryo

Cell Death and Differentiation

Volumn 6, Issue 9, 1999, Pages 908-915

  De Felici, Massimo ^a   Di Carlo, A ^a   Pesce, M ^a   Iona, S ^a   Farrace, M G ^a   Piacentini, M ^b,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Lab Embryol Cell Biol IRCCS L S   (Italy)

^c UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Apoptosis; Bax; Bcl 2; Oocytes; Primordial germ cells; SCF

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEGENERATION; EMBRYO; EMBRYO DEVELOPMENT; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEIOSIS; MOUSE; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PACHYTENE; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROPHASE;

ANIMALIA;

EID: 0032831972     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400561     Document Type: Article

References (22)

1. Gondos B (1978) Oogonia and oocytes in mammals. In: The Vertebrate Ovary, Jones R, ed (New York, Plenum Press) pp. 83-120
2. Peters H and McNatty K (1980) Atresia. In: The Ovary. Peters H, McNatty K, (eds.) New York; Granade Publishing, pp. 98-106
3. Borun K (1961) Oogenesis in the mouse. A study of the meiotic prophase. Exp. Cell Res. 24: 495-507
4. Bakken AH and McClanahan M (1978) Patterns of RNA synthesis in early meiotic prophase oocytes from fetal mouse ovaries. Chromosoma 67: 21-40
5. Pesce M, Farrace MG, Dolci S, Piacentini M and De Felici M (1993) Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis). Development 118:1089-1094
6. Coucouvanis EC, Sherwood SW, Carswell-Crumpton C, Spack E and Jones PP (1993) Evidence that the mechanism of prenatal germ cell death in the mouse is apoptosis. Exp. Cell Res. 209: 238-246
7. Pesce M and De Felici M (1994) Apoptosis in mouse primordial germ cells: a study by transmission and scanning electron microscope. Anat. Embryol. 189: 435-440.
8. Pesce M, Farrace MG, Amendola A, Piacentini M and De Felici M (1997) Stem cell factor regulation of apoptosis in mouse primordial germ cells. In: Cell Death in Reproductive Physiology. Tilly JL, Strauss JF and Tenniswood M (eds.). New York, Spinger-Verlag, pp. 19-31
9. Morita Y, Manganaro TF, Tao XJ, Martinbeau S, Donahoe PK and Tilly JL (1999) Requirement for phosphatidylinositol-3′-kinase in cytokine-mediated germ cell survival during fetal oogenesis in the mouse. Endocrinology 140: 941-949
10. De Felici M, Di Carlo A and Pesce M (1996) Role of Stem Cell Factor in somatic-germ cell interactions during prenatal oogenesis. Zygote 4: 349-351
11. Ratts V, Flaws JA, Kolp R, Sorenson C and Tilly JL (1995) Ablation of bcl-2 gene expression decreases the numbers of oocytes and primerdial follicles established in the post-natal female mouse gonad. Endocrinolocy 136: 3665-3669
12. Knudson CM, Tung KSK, Flaws JA, Brown GAJ, Tilly JL and Korsemeyer SJ (1996). Ooocyte survival but spermatocyte cell death in BAX-deficient mice. In: Proceedings from the International Symposium on Cell Death in Reproduction Physiology. Chicago, IL, USA. p. 33
13. Perez GI, Robles R, Knudson CM, Flaws JA, Korsmeyer S and Tilly JL (1999) Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency. Nature Genet. 21: 200-203
14. Watanabe M, Shirayoshi Y, Yoshimizu U, Hashimoto S, Yonehara S, Eguci Y, Tsujimoto Y and Nakatsui N (1997) Gene transfection of mouse p-imordial germ cells in vitro and analysis of their survival and growth control. Exp. Cell Res. 230: 76-83
15. Perez GI, Knudson CM, Leykin L, Kosmeyer S and Tilly JL (1997) Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nature Med. 11: 1228-1232
16. Carson WE, Haldar S, Baiocchi RA, Croce CM and Caligiuri MA (1994) The c-Kit ligand suppresses apoptosis of human natural killer cells through upregulation of bcl-2. Proc. Natl. Acad. Sci. USA 91: 7553-7557
17. Barlow C, Liyanage M, Moens PB, Deng CX, Ried T and Wynshaw-Boris A (1997) Partial rescue of the severe prophase I defects of ATM deficient-mice by p53 and p21 null alleles. Nature Genet. 17: 462-466
18. Keegan KS, Holtman DA, Plug AW, Christenson ER, Brainerd EE, Flaggs G, Bentley JN, Taylor ME, Meyn MS, Moss SB, Carr AM, Ashley T and Hoekstra MF (1996) The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes & Dev. 10: 2423-2437
19. Barlow C, Liyanage M, Moens PB, Tarsounas M, Nagashima K, Brown K, Rottinghaus S, Jackson SP, Tagle D, Ried T and Wynshaw-Boris A (1998) Atm deficiency results in severe meiotic disruption as early as leptotene of prophase I. Development 125: 4007-4017
20. De Felici M and McLaren A (1982) Isolation of mouse primordial germ cells. Exp. Cell Res. 142: 476-482
21. Pesce M and De Felici M (1995) Purification of mouse primordial germ cells by MiniMACS magnetic separation system. Dev. Biol. 170: 722-725
22. 4 feeder layers. Dev. Biol. 147: 281-284