Effect of mechanical strain on gastric cellular migration and proliferation during mucosal healing: Role of Rho dependent and Rac dependent cytoskeletal reorganisation

Gut

Volumn 45, Issue 4, 1999, Pages 508-515

  Osada, T ^a   Watanabe, S ^a   Tanaka, H ^a   Hirose, M ^a   Miyazaki, A ^a   Sato, N ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

Cell adhesion; Gastric wound healing; Migration; Proliferation; Rat RGM1 cells

Indexed keywords

ACTIN; BROXURIDINE; COLLAGEN TYPE 1; CYTOSKELETON PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; RHO FACTOR; SILASTIC; VINCULIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; GEOGRAPHIC DISTRIBUTION; IMMUNOHISTOCHEMISTRY; MECHANICAL STRESS; MUCOSA CELL; NONHUMAN; PHASE CONTRAST MICROSCOPE; PRIORITY JOURNAL; RAT; STAINING; STOMACH MUCOSA;

EID: 0032830827     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.45.4.508     Document Type: Article

References (38)

1. Minami H, McCallum RW. The physiology and pathophysiology of gastric emptying in humans. Gastroenterology 1984;86:1592-1610.
2. Tsukimi Y, Okabe S. Acceleration of healing of gastric ulcers induced in rats by liquid diet: importance of tissue contraction. Jpn J Pharmacol 1994;66:405-12.
3. Dent J, Dodds WJ, Sekiguchi T, et al. Inter digestive phasic contractions of human lower esophagial sphincter. Gastroenterology 1983;84:453-60.
4. Kobayashi I, Kawano S, Tsuji S, et al. RGMI, a cell line derived from normal gastric mucosa of rat. In Vitro Cell Dev Biol 1996;32:259-61.
5. Kinoshita Y, Nakata H, Sazzad H, et al. Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions. Gastroenterology 1995;109:1068-77.
6. Furukawa O, Nakamura E, Okabe S. Characterization of a novel cell damage model induced by acid and pepsin using gastric epithelial cells: protective effect of sucralfate. J Gastroenterol Hepatol 1997;12:115-21.
7. Tsuji S, Sawaoka H, Kawano S. Effect of NS-398, a specific inhibitor for cyclooxygenase-2, on gastric cell proliferation [abstract]. Gastroenterology 1995;108:A245.
8. Watanabe S, Hirose M, Yasuda T, et al. Role of actin and calmodulin in migration and proliferation of rabbit gastric mucosal cells in culture. J Gastroenterol Hepatol 1994;9:325-33.
9. Burridge K, Fath K. Focal contacts: transmembrane links between the extracellular matrix and the cytoskeleton. Bioessays 198;10:104-8.
10. Burridge K, Fath K, Kelly T, et al. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol 1988;4:487-525.
11. Huttenlocher A, Sandborg RR, Horwitz AF. Adhesion in cell migration. Curr Opin Cell Biol 1995;7:697-706.
12. Clark EA, Brugge JS. Integrins and signal transduction pathways: the road taken. Science 1995;268:233-9.
13. Paterson HF, Self AJ, Garrett MD, et al. Microinjection of recombinant p21rho induces rapid changes in cell morphology. J Cell Biol 1990;111:1001-7.
14. Takaishi K, Kikuchi A, Kuroda S, et al. Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol Cell Biol 1993;13:72-9.
15. Kishi K, Sasaki T, Kuroda S, et al. Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein. J Cell Biol 1990;120:1187-95.
16. Yoshioka K, Matsumura F, Akedo H, et al. Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells. J Biol Chem 1998;273:5146-51.
17. Hall A. Rho GTPases and the actin cytoskeleton. Science 1998;279:509-14.
18. Banes AJ, Gilbert J, Taylor D, et al. A new vacuum-operated stress-providing instrument that applies static or variable duration cycle tension or compression to cells in vitro. J Cell Sci 1985;75:35-42.
19. Banes AJ, Link GVW, Gilbert J, et al. Culturing cells in mechanically active environment. American Biotechnology Laboratory 1990;8:12-22.
20. Rosales OR, Sumpio, BE. Changes in cyclic strain increase inositol triphosphate and diacylglycerol in endothelial cells. Am J Physiol 1992;262:C956-62.
21. Gratzner HG. Monoclonal antibody to 5-bromo- and 5-indo-deoxyuridine: a new reagent for detection of DNA replication. Science 1982;218:474-5.
22. Cooper JA, Blum JD, Pollard TD. Acanthamoeba castellaniii capping protein: properties, mechanism or action, immunologic cross-reactivity, and localization. J Cell Biol 1984;99:217-25.
23. Asijee GM, Sturk A, Bruin T, et al. Vinculin is a permanent component of the membrane skeleton and incorporated into the (re)organizing cytoskeleton upon platelet activation. Eur J Biochem 1990;189:131-6.
24. Kwong NK, Brown BH, Whittaker GE, et al. Electrical activity of the gastric antrum in man. Br J Surg 1970;12:913-16.
25. Couturier D, Rose C, Paologgi J, et al. Electrical activity of the normal human stomach. A comparative study of recordings obtained from serosal and mucosal sides. Dig Dis Sci 1972;17:969-76.
26. Weber J, Kohatsu S. Pacemaker localization and electrical conduction patterns in the canine stomach. Gastroenterology 1970;59:717-26.
27. Kelly KA, Code CF. Canine gastric pacemaker. Am J Physiol 1971;220:112-18.
28. Synnerstad I, Ekblad E, Sundler F, et al. Gastric mucosal smooth muscles may explain oscillations in glandular pressure: role of vasoactive intestinal peptide. Gastroenterology 1998;114:284-94.
29. Watanabe S, Xian-En Wang, Hirose M, et al. Basic fibroblast growth factor accelerates gastric mucosal repair in vitro by promoting mesenchymal cell migration and proliferation. J Gastroenterol Hepatol 1995;10:627-32.
30. Watanabe S, Xian-En Wang, Hirose M, et al. Effect of myosin light chain kinase inhibitor wortmannin on the wound repair of cultured gastric mucosal cells. Biochem Biophys Res Commun 1994;199:799-806.
31. Mikami H, Watanabe S, Hirose M, et al. Role of extracellular matrix in wound repair by cultured gastric mucosal cells. Biochem Biophys Res Commun 1991;202:285-92.
32. Watanabe S, Xian-En Wang, Hirose M, et al. Platelet-derived growth factor accelerates gastric epithelial restoration in a rabbit cultured cell model. Gastroenterology 1996;110:775-9.
33. Basson MD, Li GD, Hong F, et al. Amplitude-dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco-2 monolayers. J Cell Physiol 1996;168:476-88.
34. Chen Q, Kinch MS, Lin TH, et al. Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J Biol Chem 1994;269:26602-5.
35. Miyamoto S, Teramoto H, Coso OM, et al. Integrin function: molecular hierarchies of cytoskeletal and signal molecules. J Cell Biol 1995;131:791-805.
36. Machesky LM, Hall A. Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskektal reorganization. J Cell Biol 1997;138:913-26.
37. Santos MF, McCormack SA, Guo Z, et al. Rho proteins play a critical role in cell migration during the early phase of mucosal restitution. J Clin Invest 1997;100:216-25.
38. Ermly W, Qing M, Krishnankutty S, et al. Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF. J Cell Biol 1993;123:741-7.