Leptin concentrations in cord blood in normal newborn infants and offspring of diabetic mothers

Hormone and Metabolic Research

Volumn 31, Issue 8, 1999, Pages 467-471

  Persson, Bengt ^a,b   Westgren, M ^b   Celsi, G ^a   Nord, E ^a   Ortqvist E ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

C peptide; Gestational Diabetes Mellitus; Leptin; Newborn Infants; Type 1 Diabetes Mellitus

Indexed keywords

C PEPTIDE; HEMOGLOBIN A1C; LEPTIN;

ARTICLE; BODY FAT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FETUS GROWTH; HUMAN; HYPERINSULINEMIA; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; LOW BIRTH WEIGHT; MALE; NEWBORN; PLACENTA WEIGHT; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; REGULATORY MECHANISM; UMBILICAL CORD BLOOD;

EID: 0032830548     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978776     Document Type: Article

References (27)

1. 1 Masuzaki H, Ogawa Y, Sagawa N, et al. Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans. Nature Med 1997; 3: 1029-1033
2. 2 Senaris R, Garcia-Caballero T, Casabiell X, et al. Synthesis of leptin in human placenta. Endocrinology 1997; 138: 4501-4504
3. 3 Schubring C. Kiess W, Englaro P, Rascher W, Blum W. Leptin concentrations in amniotic fluid, venous and arterial cord blood and maternal serum: high leptin synthesis in the fetus and inverse correlation with placental weight. Eur J Pediatr 1996; 155: 830-834
4. 4 Schubring C, Kiess W, Englaro P, et al. Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: relation to neonatal and placental weight. J Clin Endocrinol Metab 1997; 82: 1480-1483
5. 5 Matsuda J, Yokota I, Iida M, Murakami T, et al. Serum leptin concentration in cord blood-relationship to birth weight and gender. J Clin Endocrinol Metab 1997; 82: 1642-1644
6. 6 Sivan E, Lin WM, Homko CJ, Reece EA, Boden G. Leptin is present in human cord blood. Diabetes 1997; 46: 917-919
7. 7 Hartman BW, Wagenbichler P, Söregi G. Maternal and umbilical-cord serum leptin concentrations in normal, full-term pregnancies. N Engl J Med 1997; 337: 863
8. 8 Rentsch J, Chiese M. Regulation of ob mRNA levels in culture adipocytes. FEBS Lett 1996; 379: 55-59
9. 9 Utriainen T, Malmström R, Mäkimattila S, Yki-Järvinen H. Supra-physiological hyperinsulinemia increases plasma leptin concentrations after 4h in normal subjects. Diabetes 1996; 45: 1364-1366
10. 10 Kieffer TJ, Heller RS, Habener JF. Leptin receptors expressed on pancreatic beta-cells. Biochem Biophys Res Commun 1996; 224: 522-527
11. 11 Islam S, Morton NM, Hanson A, Emilsson V. Rat insulinoma-derived pancreatic B-cells express a functional leptin receptor that mediates a proliferative response. Biochem Biophys Res Commun 1997; 238: 851-855
12. 12 Persson B, Hanson U. Fetal size at birth in relation to quality of blood glucose control in pregnancies complicated by pregestational diabetes mellitus. Br J Obstet Gynec 1996; 103: 427-433
13. 13 Gross GA, Solenberger T, Philpott T, Holcomb WL, Landt M. Plasma leptin concentrations in newborns of diabetic and nondiabetic mothers. Am J Perinatol 1998; 15: 243-247
14. 14 Lepercq J, Cauzac M, Lahlou N, Timisit J, Girard J, Auwerx J, Haugeul-de Mouzon S, Rapid publication. Overexpression of placental leptin in diabetic pregnancy. Diabetes 1998; 47: 847-850
15. 15 Shekhawt PS, Garland JS, Shivpuri C, Mick GJ, Sasidharan P, Peltz CJ, McCormick KL Neonatal cord blood leptin: its relationship to birth weight, body mass index, maternal diabetes and steroids. Pediatr Res 1998; 43: 338-343
16. 16 Persson B, Stangenberg M, Hanson U, Nordlander E. Gestational diabetes mellitus (GDM). Comparative evaluation of two treatment regimens, diet versus insulin and diet. Diabetes 1985; 34: 101-105
17. 17 Heding L. Radioimmunological determination of C-peptide in serum. Diabetologia 1975; 11: 541-548
18. 18 Mc Cance RA, Widdowson EM. Fat (review). Pediatric Res 1977; 11: 1081-1083
19. 19 Merklin RJ. Growth and distribution of human fetal brown fat. Anatomical Record 1974; 178; 637-645
20. 20 Enzi G, Zanardo V, Caretta F, Inelmen EM, Rubaltelli F. Intrauterine growth and adipose tissue development. Am J Clin Nutr 1981; 34: 1785-1790
21. 21 Wolfe HM, Brans YW, Gross TL, Bhatia RK. Sokol RJ. Correlation of commonly used measures of intrauterine growth with estimated neonatal body fat. Biol Neonate 1990; 57: 167-171
22. 22 Farr V. Skinfold thickness as an indication of maturity of the newborn. Arch Dis Child 1966; 41: 301-308
23. 23 Saladin R, De Vos P, Guerre-Millo M, et al. Transient increase in the obese gene expression after food intake or insulin administration. Nature 1995; 377: 527-529
24. 24 Heding LG, Persson B, Stangenberg M. B-cell function in newborn infants of diabetic mothers. Diabetologia 1980; 19: 427-432
25. 25 Koistinen HA, Koivisto VA, Andersson S, et al. Leptin concentrations in cord blood correlates with intrauterine growth. J Clin Endocrinol Metab 1997; 82: 3328-3330
26. 26 Whitelaw A. Subcutaneous fat in newborn infants of diabetic mothers. An indication of quality of diabetic control. Lancet 1977; 1: 15-18
27. 27 Persson B, Centz J, Stangenberg M. Neonatal problem. Sutherland HW, Stowers JM (eds). Carbohydrate metabolism in pregnancy and the newborn. Berlin Springer Verlag 1979: 376-391