Molecular, morphometric and functional analyses demonstrate that the growth hormone deficient little mouse is not hypomyelinated

Developmental Brain Research

Volumn 116, Issue 2, 1999, Pages 191-199

  Lehman, D M ^a   Hale, D E ^b   Cody, J T ^c   Harrison, J M ^b   Leach, R J ^a,b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c WILFORD HALL MEDICAL CENTER   (United States)

Author keywords

Flash visual evoked potential; Growth hormone; Myelin basic protein; Myelination; Proteolipid protein

Indexed keywords

GROWTH HORMONE; MYELIN; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN; SOMATOMEDIN;

ARTICLE; BRAIN GROWTH; BRAIN SIZE; CORPUS CALLOSUM; EVOKED VISUAL RESPONSE; FEMALE; GROWTH HORMONE DEFICIENCY; MALE; MOUSE; MYELIN SHEATH; MYELINATION; NERVE CELL GROWTH; NEWBORN; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; AXONS; FEMALE; GROWTH HORMONE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN BASIC PROTEINS; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH;

EID: 0032828719     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(99)00081-4     Document Type: Article

References (38)

1. Almazan G., Honegger P., Matthieu J.-M., Guentert-Lauber B. Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture. Dev. Brain Res. 21:1985;257-264.
2. Barbarese E., Nielson M.L., Carson J.H. The effect of the shiverer mutation on myelin basic protein expression in homozygous and heterozygous mouse brain. J. Neurochem. 40:1983;1680-1686.
3. Beck K.D., Powell-Braxton L., Widmer H.-R., Valverde J., Hefti F. Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron. 14:1995;717-730.
4. Bilbool N., Kaitz M., Feinsod M., Soffer D., Abramsky O. Visual evoked potentials in experimental allergic encephalomyelitis. J. Neurol. Sci. 60:1983;105-115.
5. Carson J.H., Nielson M.L., Barbarese E. Developmental regulation of myelin basic protein expression in mouse brain. Dev. Biol. 96:1983;485-492.
6. Carson M.J., Behringer R.R., Brinster R.L., McMorris F.A. Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron. 10:1993;729-740.
7. F.L. Carson, Nuclear and cytoplasmic staining, in: Histotechnology. A self-instructional text, American Society of Clinical Pathologists Press, Chicago, 1997, pp. 96-97.
8. Cheng C.M., Joncas G., Reinhardt R.R., Farrer R., Quarele R., Janssen J., McDonald M.P., Crawley J.N., Powell-Braxton L., Bondy C.A. Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition. J. Neurosci. 18:1998;5673-5681.
9. Chomzynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 16:1987;156-159.
10. Church G.M., Gilbert W. Genomic sequencing. Proc. Natl. Acad. Sci. USA. 81:1984;1991-1995.
11. Cody J.D., Hale D.E., Brkanac Z., Kaye C.I., Leach R.J. Growth hormone insufficiency associated with haploinsufficiency at 18q23. Am. J. Med. Genet. 71:1997;420-425.
12. Cowan N.J., Dobner P.R., Fuchs E.V., Cleveland W. Expression of human alpha-tubulin genes: interspecies conservation of 3′ untranslated regions. Mol. Cell. Biol. 3:1983;1738-1745.
13. D'Ercole A.J., Zonghan D., Xing Y., Boney C., Wilkie M.B., Lauder J.M., Han V.D.M., Clemmons D.R. Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: an in vivo model for the analysis of igf function in the brain. Dev. Brain Res. 82:1994;213-222.
14. Duwaer A.L., Spekreijse H. Latency of luminance and contrast evoked potentials in multiple sclerosis patients. Electroencephalogr. Clin. Neurophysiol. 45:1978;244-258.
15. Estrada J.C., Brinn N.T., Bossen E.H. A rapid method of staining ultrathin sections for surgical pathology TEM with the use of the microwave oven. Am. J. Clin. Pathol. 83:1985;639-641.
16. Frommer G.P., Galambos R., Norton T.T. Visual evoked responses in cats with optic tract lesions. Exp. Neurol. 21:1968;346-363.
17. Gay C.T., Hardies L.J., Rauch R.A., Lancaster J.L., Plaetke R., DuPont B.R., Cody J.D., Cornell J.E., Herndon R.C., Ghidoni P.D., Schiff J.M., Kaye C.I., Leach R.J., Fox P. Magnetic resonance imaging demonstrates incomplete myelination in the 18q-syndrome: evidence for myelin basic protein haploinsufficiency. Neuropsyc. Genet. 74:1997;422-431.
18. Ghidoni D.P., Hale D.E., Cody J.D., Gay C.T., Thompson N.M., McClure E.B., Danney M.M., Leach R.J., Kaye C.I. Growth hormone deficiency associated with the 18q-syndrome. Am. J. Med. Genet. 69:1997;7-12.
19. Godfrey P., Rahal J.O., Beamer W.G., Copeland N.G., Jenkins N.A., Mayo K.E. GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function. Nat. Genet. 4:1993;227-232.
20. M.A. Hayat, Staining, in: Principles and Techniques of Electron Microscopy, Biological Applications 1, Van Nostrand-Reinhold, New York, 1970, pp. 262-264, 345.
21. Kaye C.I., Cody J.D., Schaub R.L., Leach R.J., Hale D.E. Endocrine abnormalities in children with 18q-syndrome. Am. J. Hum. Genet. 63S:1998;A602.
22. Lehman D.M., Mayo K.E., Hale D.E., Cody J.T., Poole T.M., Leach R.J. PCR typing of little mouse mutation. Mouse Genome. 95:1997;689-691.
23. D.M. Lehman, J.M. Harrison, Flash visual evoked potentials of hypomyelinated shiverer mice, in: Vision Science and Its Applications, OSA Technical Digest Series, Optical Society of America, Washington, DC, 1999, pp. 254-257.
24. Mathews L.S., Hammer R.E., Brinster R.L., Palmiter R.D. Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology. 123:1988;433-437.
25. Molineaux S.M., Engh H., DeFerra F., Hudson L., Lazzarini R.A. Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation. Proc. Natl. Acad. Sci. USA. 83:1986;7542-7546.
26. Mozell R.L., McMorris F.A. Insulin-like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures. J. Neurosci. Res. 30:1991;382-390.
27. Noguchi T., Sugisaki T., Tsukada Y. Microcephalic cerebrum with hypomyelination in the growth hormone-deficient mouse (lit). Neurochem. Res. 10:1985;1097-1106.
28. Noguchi T., Sugisaki T., Kudo M., Satoh I. Retarded growth of the suprachiasmatic nucleus and pineal body in dw and lit dwarf mice. Dev. Brain Res. 26:1986;161-172.
29. Noguchi T., Sugisaki T., Nishikawa N., Tsukada Y. Restoration of microcephalic cerebrum with hypomyelination in the growth hormone-deficient mouse (lit): stimulatory effects of GH restricted to the first 20 days of postnatal life. Neurochem. Res. 13:1988;249-252.
30. Noguchi T. Retarded cerebral growth of hormone-deficient mice. Comp. Biochem. Physiol. 98C:1991;239-248.
31. Nyberg F., Burman P. Growth hormone and its receptors in the central nervous system - location and functional significance. Horm. Res. 45:1996;18-22.
32. Readhead C., Popko B., Takahashi N., Shine D.H., Saavedra R.A., Sidman R.L., Hood L. Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell. 48:1987;713-721.
33. Shine H.D., Readhead C., Popko B., Hood L., Sidman R.L. Morphometric analysis of normal, mutant, and transgenic CNS: correlation of myelin basic protein expression to myelinogenesis. J. Neurochem. 58:1992;342-349.
34. Skoff R.P., Ghandour M.S. Oligodendroctyes in female carriers of the jimpy gene make more myelin than normal oligodendrocytes. J. Comp. Neurol. 355:1995;124-133.
35. Sorg B.A., Smith M.M., Campagnoni A.T. Developmental expression of the myelin proteolipid protein and basic protein mRNAs in normal and dysmyelinating mutant mice. J. Neurochem. 49:1987;1146-1154.
36. Wajnrajch M.P., Gertner J.M., Harbison M.D., Chua S.C. Jr., Leibel R.L. Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse. Nat. Genet. 12:1996;88-90.
37. Woods K.A., Camacho-Hubner C., Savage M.O., Clark A.J.L. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor 1 gene. New Engl. J. Med. 335:1996;1363-1367.
38. Ye P., Carson J., D'Ercole A.J. In vivo actions of insulin-like growth factor-1 (IGF-1) on brain myelination: studies of IGF-1 and IGF binding protein-1 (IGFBP-1) transgenic mice. J. Neurosci. 15:1995;7344-7356.