Localized increase in nitric oxide production and the expression of nitric oxide synthase isoforms in rat uterus with experimental intrauterine infection

American Journal of Obstetrics and Gynecology

Volumn 181, Issue 3, 1999, Pages 601-609

  Fang, Li ^a   Nowicki, Bogdan J ^a   Dong, Yuan Lin ^a   Yallampalli, Chandrasekhar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Intrauterine infection; Nitric oxide; Nitric oxide synthase; Rat

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; EXPERIMENTAL MODEL; FEMALE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTRAUTERINE INFECTION; NONHUMAN; PRIORITY JOURNAL; RAT; UTERUS;

EID: 0032828153     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(99)70499-0     Document Type: Article

References (32)

1. 1. Gibbs RS, Romero R, Hillier SL, Eschenbach DA, Sweet RL. A review of preterm birth and subclinical infection. Am J Obstet Gynecol 1992;166:1515-28.
2. 2. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-42.
3. 3. Yallampalli C, Dong YL, Gangula PR, Fang L. Role and regulation of nitric oxide in the uterus during pregnancy and parturition. J Soc Gynecol Investig 1998;5:58-67.
4. 4. Forstermann U, Kleinert H. Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn Schmiedebergs Arch Pharmacol 1995;352:351-64.
5. 5. Payen D, Bernard C, Beloucif S. Nitric oxide in sepsis. Clin Chest Med 1996;17:333-50.
6. 6. Fang FC. Mechanisms of nitric oxide-related antimicrobial activity. J Clin Invest 1997;99:2818-25.
7. 7. Tiao G, Rafferty J, Ogle C, Fischer JE, Hasselgren PO. Detrimental effect of nitric oxide synthase inhibition during endotoxemia may be caused by high levels of tumor necrosis factor and interleukin-6. Surgery 1994;116:332-7.
8. 8. Dykhuizen RS, Masson J, McKnight G, Mowat AN, Smith CC, Smith LM, et al. Plasma nitrate concentration in infective gastroenteritis and inflammatory bowel disease. Gut 1996;39:393-5.
9. 9. Fukastu K, Saito H, Fukushima R, Inoue T, Lin MT, Inaba T, et al. Detrimental effects of nitric oxide synthase inhibitor in a murine sepsis model. Arch Surg 1995;130:410-4.
10. 10. Evans TG, Thai L, Granger DL, Hibbs JB Jr. Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis. J Immunol 1993;151:907-15.
11. 11. Stenger S, Donhauser N, Thuring H, Rollinghoff M, Bogdan C. Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J Exp Med 1996;183:1501-14.
12. 12. Granger DL. Macrophage production of nitrogen oxides in host defense against microorganisms. Res Immunol 1991;142;7:570-72.
13. 13. Yallampalli C, Garfield RE, Byam-Smith M. Nitric oxide inhibits uterine contractility during pregnancy but not during delivery. Endocrinology 1993;133:1899-902.
14. 14. Nowicki BJ, Fang L, Singhal J, Nowicki S, Yallampalli C. Lethal outcome of uterine infection in pregnant but not in nonpregnant rats and increased death rate with inhibition of nitric oxide. Am J Reprod Immunol 1997;38:309-12.
15. 15. Hirsch E, Saotome I, Hirsh D. A model of intrauterine infection and preterm delivery in mice. Am J Obstet Gynecol 1995;172:1598-603.
16. 16. Nicholson S, Bonecini-Almeida M da G, Lapa e Silva JR, Nathan C, Xie QW, Mumford R, et al. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J Exp Med 1996;183:2293-302.
17. 17. Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW, et al. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc Natl Acad Sci U S A 1993;90:9730-4.
18. 18. Wu J, Lin Q, Willis WD. Nitric oxide contributes to sensitization following intradermal injection of capsaicin. Neuroreport 1998;9:589-92.
19. 19. Olson LM, Jones-Burton CM, Jablonka-Shariff A. Nitric oxide decreases estradiol synthesis of rat luteinized ovarian cells: possible role for nitric oxide in functional luteal regression. Endocrinology 1996;137:3531-9.
20. 20. Stuehr DJ, Marletta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci U S A 1985;82:7738-42.
21. 21. Zhang RS, Guth PH, Scremin OU, Singh R, Pervin S, Chaudhuri G. Regulation of endometrial blood flow in ovariectomized rats: assessment of the role of nitric oxide. Am J Physiol 1997;273:H2009-17.
22. 22. De Groote MA, Granger D, Xu Y, Campbell G, Prince R, Fang FC. Genetic and redox determinants of nitric oxide cytotoxicity in a Salmonella typhimurium model. Proc Natl Acad Sci U S A 1995;2:6399-403.
23. 23. Adams LB, Hibbs JB Jr, Taintor RR, Krahenbuhl JL. Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii: Role for synthesis of inorganic nitrogen oxides from L-arginine. J Immunol 1990;144:2725-9.
24. 24. Sternberg J, Mabbott N, Sutherland I, Liew FY. Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection. Infect Immun 1994;62:2135-7.
25. 25. Ochoa JB, Udekwu AO, Billiar TR, Curran RD, Cerra FB, Simmons RL, et al. Nitrogen oxide levels in patients after trauma and during sepsis. Ann Surg 1991;214:621-6.
26. 26. Kumar V, Jindal SK, Ganguly NK. Release of reactive oxygen and nitrogen intermediates from monocytes of patients with pulmonary tuberculosis. Scand J Clin Lab Invest 1995;55: 163-9.
27. 27. Wheeler MA, Smith SD, Garcia-Cardena G, Nathan C, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. J Clin Invest 1997;99:110-6.
28. 28. Yelavarthi KK, Chen HL, Yang YP, Cowley BD Jr, Fishback JL, Hunt JS. Tumor necrosis factor-alpha mRNA and protien in rat uterine and placental cells. J Immunol 1991;146:3840-8.
29. 29. Head JR, Kresge CK, Young JD, Hiserodt JC. NKR-P1 + cells in the rat uterus: granulated metrial gland cells are of the natural killer cell lineage. Biol Reprod 1994;51:509-23.
30. 30. Sladek SM, Kanbour-Shakir A, Watkins S, Berghorn KA, Hoffman GE, Roberts JM. Granulated metrial gland cells contain nitric oxide synthases during pregnancy in the rat. Placenta 1998;19:55-65.
31. 31. Anstey NM, Weinberg JB, Hassanali MY, Mwaikambo ED, Manyenga D, Misukonis MA, et al. Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med 1996;184:557-67.
32. 32. Green SJ, Nacy CA, Schreiber RD, Granger DL, Crawford RM, Meltzer MS, et al. Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in mycobacterium bovis BCG-treated mice. Infect Immun 1993;61:689-98.