Characterization of P2 receptors modulating neural activity in rat rostral ventrolateral medulla

Neuroscience

Volumn 94, Issue 3, 1999, Pages 867-878

  Ralevic, V ^a   Thomas, T ^a   Burnstock, G ^a   Spyer, K M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

ATP; P2 receptors; Rostral ventrolateral medulla

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ADENOSINE 5' O (2 THIODIPHOSPHATE); ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR RESPONSE; DESENSITIZATION; MALE; MEDULLA OBLONGATA; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; RECEPTOR DENSITY; THALAMUS VENTRAL NUCLEUS;

EID: 0032826507     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00376-0     Document Type: Article

References (33)

1. Burnstock G. Development and perspectives of the purinoceptor concept. J. auton. Pharmac. 16:1996;295-302.
2. Burnstock G., King B.F. Numbering of cloned P2 purinoceptors. Drug Dev. Res. 38:1996;67-71.
3. 2X purinoceptor expressed by a subset of sensory neurones. Nature. 377:1995;428-431.
4. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16:1996;2495-2507.
5. Edwards F.A., Gibb A.J., Colquhoun D. ATP receptor mediated synaptic currents in the central nervous system. Nature. 359:1992;144-146.
6. 2-purinoceptors in the nucleus tractus solitarius mediate depressor responses. Neurosci. Lett. 174:1994;188-192.
7. Evans R.J., Surprenant A. P2X receptors in autonomic and sensory neurones. Semin. Neurosci. 8:1996;217-223.
8. Fredholm B.B., Burnstock G., Harden K.T., Spedding M. Receptor nomenclature. Drug Dev. Res. 39:1996;461-466.
9. Guyenet P. G. (1990) Role of the ventral medulla oblongata in blood pressure regulation. In Central Regulation of Autonomic Functions (eds Loewy A. D. and Spyer K. M.), pp. 145-167. Oxford University Press, Oxford.
10. 2Y purinoceptor-operated potassium channel is possibly regulated by the βγ subunits of a pertussis toxin-insensitive G-protein in cultured rat inferior colliculus neurones. Biochem. biophys. Res. Commun. 214:1995;589-596.
11. 2-purinoceptor-operated potassium channel in rat cerebellar neurones. Biochem. biophys. Res. Commun. 218:1996;67-71.
12. Illes P., Nieber K., Nörenberg W. Electrophysiological effects of ATP on brain neurones. J. auton. Pharmac. 16:1996;407-411.
13. Inoue K., Nakazawa K., Fujimori K., Watano T., Takanaka A. Extracellular adenosine-5′-triphosphate-evoked glutamate release in cultured hippocampal neurones. Neurosci. Lett. 134:1992;215-218.
14. Jordan D. (1995) Central nervous integration of cardiovascular control. In Cardiovascular Regulation (eds Jordan D. and Marshall J.), pp. 1-14. Cambridge University Press, Cambridge.
15. 2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J. Physiol., Lond. 484:1995;385-395.
16. 3 receptor subunits can account for ATP-gated currents in sensory neurones. Nature. 377:1995;432-435.
17. Nakazawa K., Inoue K., Ito K., Koizumi S., Inoue K. Inhibition by suramin and reactive blue 2 of GABA and glutamate receptor channels in rat hippocampal neurones. Naunyn-Schmiedeberg's Arch. Pharmac. 351:1995;202-208.
18. Nieber K., Poelchen W., Illes P. Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat. Br. J. Pharmac. 122:1997;423-430.
19. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd edn. Academic, New York.
20. Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmac. Rev. 50:1998;413-492.
21. Ralevic V., Thomas T., Burnstock G., Spyer K.M. P2 receptor-mediated changes in activity of neurones in the rostral ventrolateral medulla of the rat: an in vivo ionophoretic study. J. auton. nerv. Syst. 65:1997;104.
22. Ralevic V., Thomas T., Spyer K.M. Effects of P2 purine receptor agonists microinjected into the rostral ventrolateral medulla on the cardiovascular and respiratory systems of the anaesthetised rat. J. Physiol., Lond. 509P:1998;127P.
23. 2X-purinoceptor in cultured neurones of the rat dorsal root ganglia. Br. J. Pharmac. 118:1996;951-956.
24. Spyer K.M. Central nervous mechanisms contributing to cardiovascular control. J. Physiol., Lond. 474:1994;1-19.
25. St Lambert J.H., Thomas T., Burnstock G., Spyer K.M. A source of adenosine involved in cardiovascular responses to defense area stimulation. Am. J. Physiol. 272:1997;R195-R200.
26. Sun M.K. Pharmacology of reticulospinal vasomotor neurones in cardiovascular regulation. Pharmac. Rev. 48:1996;465-494.
27. Sun M.K., Wahlestedt C., Reis D.J. Action of externally applied ATP on rat reticulospinal vasomotor neurones. Eur. J. Pharmac. 224:1992;93-96.
28. Thomas T., Spyer K.M. A novel influence of adenosine on ongoing activity in rat rostral ventrolateral medulla. Neuroscience. 88:1999;1213-1223.
29. Todorov L., Mihaylova-Todorova S., Westfall T.D., Sneddon P., Kennedy C., Bjur R.A., Westfall D.P. Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation. Nature. 387:1997;76-79.
30. Vulchanova L., Arvidsson U., Riedl M., Wang J., Buell G., Surprenant A., North R.A., Elde R. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc. natn. Acad. Sci. USA. 93:1996;8063-8067.
31. Zagon A., Spyer K.M. Stimulation of aortic nerve evokes three different response patterns in neurones of rostral VLM of the rat. Am. J. Physiol. 271:1996;R1720-R1728.
32. 2Y purinoceptors in the rat striatum. Brain Res. 691:1995;205-212.
33. Zimmermann H. Signalling via ATP in the nervous system. Trends Neurosci. 17:1994;420-426.