Nitration of proteins in bronchoalveolar lavage fluid from patients with acute respiratory distress syndrome receiving inhaled nitric oxide

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 3, 1999, Pages 1031-1034

  Lamb, Nicholas J ^a   Quinlan, Gregory J ^a   Westerman, Sarah T ^a   Gutteridge, John M C ^a   Evans, Timothy W ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; NITRIC OXIDE; PEROXYNITRITE; PROTEIN; SUPEROXIDE;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; CLINICAL ARTICLE; CYTOTOXICITY; DOSE RESPONSE; FEMALE; GAS EXCHANGE; HUMAN; LEUKOCYTE ACTIVATION; LUNG INJURY; LUNG LAVAGE; LUNG VASCULAR RESISTANCE; MALE; NITRATION; PNEUMONIA; PRIORITY JOURNAL;

EID: 0032825511     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.3.9810048     Document Type: Article

References (21)

1. Delinger, P. R., J. L. Zimmerman, R. W. Taylor, R. C. Straube, D. L. Hauser, G. J, Criner, K. Davis, Jr., T. M. Hyers, P. Papadakos, and the Inhaled Nitric Oxide in ARDS Group. 1998. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomised phase II trial. Crit. Care Med. 26:15-23.
2. Collet-Martin, S., C. Gatecel, N. Kermarrec, M. A. Gougerot-Pocidalo, and D. Payen. 1996. Alveolar neutrophil functions and cytokine levels in patients with the adult respiratory distress syndrome during nitric oxide inhalation. Am. J. Respir. Crit. Care Med. 153:985-990.
3. O'Donnell, V. B., P. H. Chumley, N. Hogg, A. Bloodworth, V. M. Dacley-Usmar, and B. A. Freeman. 1997. Nitric oxide inhibition of lipid peroxidation: kinetics of reaction with lipid peroxyl radicals and comparison with alpha-tocopherol. Biochemistry 36:15216-15223.
4. Blough, N., and O. Zafiriou. 1985. Reaction of superoxide with nitric oxide to form peroxynitrite in alkaline aqueous solutions. Inorg. Chem. 24:3502-3504.
5. Pryor, W. A., and G. L. Squadrito. 1995. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268:L699-L722.
6. Haddad, I. Y., G. Pataki, P. Hu, C. Galliani, J. S. Beckman, and S. Matalon. 1994. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J. Clin. Invest. 94:2407-2413.
7. Lamb, N. J., J. M. C. Gutteridge, C. Baker, T. W. Evans, and G. J. Quinlan. 1998. Oxidative damage to proteins in bronchoalveolar lavage fluid in patients with ARDS: evidence for neutrophil-mediated hydroxylation, nitration and chlorination. Crit. Care Med. (In press)
8. Cuthbertson, B. H., P. Dellinger, O. J. Dyar, T. W. Evans, T. Higenbotham, R. Latimer, D. Payen, S. A. Stott, N. Webster, and J. D. Young. 1997. UK guidelines for the use of inhaled nitric oxide therapy in adult IUCs. Intensive Care Med. 23:1212-1218.
9. Halsam, P. L., D. A. Hughes, P. D. MacNaughton, C. S. Baker, and T. W. Evans. 1994. Surfactant replacement therapy in late-stage adult respiratory distress syndrome. Lancet 343:1009-1011.
10. Ketting, K. D., S. K. Wadman, I. J. Spanpen, S. B. Van der Meer, and M. Duran. 1991. Gas chromatography method for the separation of amino acids emantiomers in plasma and urine: application in a case of short bowel syndrome. Clin. Chim. Acta 204:79-86.
11. van der Vliet, A., C. A. O'Neil, B. Halliwell, C. E. Cross, and H. Kaur. 1994. Aromatic hydroxylation and nitration of phenylalanine and lyrosine by peroxynitrite: evidence for hydroxyl radical production peroxynitrite. FEBS Lett. 339:89-92.
12. Beckman, J. S., T. W. Beckman, J. Chen, P. A. Marshall, and B. A. Freeman. 1990. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U.S.A. 87:1620-1624.
13. Hogg, N., V. M. Darley-Usmar, M. T. Wilson, and S. Modcada. 1992. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide. Biochem. J. 281:419-424.
14. Kaur, H., M. Whiteman, and B. Halliwell. 1997. Peroxynitrite-dependent aromatic hydroxylation and nitration of salicylate and phenylalanine: is hydroxyl radical involved? Free Radical Res. 26:71-82.
15. Gow, A., D. Duran, S. R. Thorn, and H. Ischiropoulos. 1996. Carbon dioxide enhancement of peroxynitrite-mediated protein tyrosine nitration. Arch. Biochem. Biophys. 333:42-48.
16. Haddad, I. Y., S. Zhu, J. Crow, E. Barefield, T. Gadihe, and S. Matalon. 1996. Inhibition of alveolar type II ATP and surfactant synthesis by nitric oxide. Am. J. Physiol. 270:L898-L906.
17. Matalon, S., V. DeMarco, I. Y. Haddad, C. Myles, J. W. Skimming, S. Schurch, S. Cheng, and S. Cassin. 1996. Inhaled nitric oxide injures the pulmonary surfactant system of lambs in vivo. Am. J. Physiol. 270:L273-L280.
18. Eiserich, J. P., C. E. Cross, A. D. Jones, B. Halliwell, and A. van der Vliet. 1996. Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid: a novel mechanism for nitric oxide-mediated protein modification. J. Biol. Chem. 271:19199-19208.
19. Haddad, I. Y., S. Zhu, H. Ischiropoulos, and S. Matalon. 1996. Nitration of surfactant protein A results in decreased ability of aggregate lipids. Am. J. Physiol. 270:L281-L288.
20. Zhu, S., M. Manuel, I. Haddad, and S, Matalon. 1998. Mechanisms of nitric oxide induced injury to the alveolar epithelium. In S. Matalon and J. I. Sznajder, editors. Acute Respiratory Distress Syndrome: Cellular and Molecular Mechanisms and Clinical Management. NATO ASI series, Vol. 297. Plenum Press New York. 345-354.
21. Kamisaki, Y., K. Wada, M. Ataka, Y. Yamada, K. Nakamoto, K. Ashida, and Y. Kishimoto. 1997. Lipopolysaccharide-induced increase in plasma nitrotyrosine concentrations in rats. Biochim. Biophys. Acta 1362:24-28.