Intravitreal dexamethasone in exogenous bacterial endophthalmitis: Results of a prospective randomised study

British Journal of Ophthalmology

Volumn 83, Issue 9, 1999, Pages 1050-1055

  Das, Taraprasad ^a   Jalali, Subhadra ^a   Gothwal, Vijaya K ^a   Sharrna, Savitri ^a   Naduvilath, Thomas J ^a  

^a L V PRASAD EYE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; DEXAMETHASONE;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ENDOPHTHALMITIS; FEMALE; HUMAN; INFLAMMATION; INTRAVITREAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; VISUAL ACUITY; VITRECTOMY;

EID: 0032825263     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.83.9.1050     Document Type: Article

References (24)

1. Graham RO, Peyman GA, Intravitreal injection of dexamethasone: treatment of experimentally induced endophthalmitis. Arch Ophthalmol 1974;92:149-54.
2. Peyman GA, Herbst R. Bacterial endophthalmitis; treatment with intraocular injection of gentamicin and dexamethasone.Arch Ophthalmol 1974;92:416-18.
3. Diamond JG. Intraocular management of endophthalmitis: a systemic approach. Ophthalmol 1981;99:96-9.
4. Meredith TA, Aguilar E, Miller MJ, et al. Comparative treatment of experimental Staphylococcus epidermidis endophthalmitis. Arch Ophthalmol 1990;108:857-60.
5. Schulman JA, Peyman GA. Intravitreal corticosteroids as an adjunct in the treatment of bacterial and fungal endophthalmitis: a review. Retina 1992;12:336-40.
6. Irvine WD, Flynn HW, Miller D, et al Endophthalmitis caused by gram negative organism. Arch Ophthalmol 1992; 110:1450-4.
7. Doft BH, The endophthalmitis vitrectomy study. Arch Ophthalmol 1991; 109:487-9.
8. Endophthalmitis Vitrectomy Study Group. Results of the Endophthalmitis Vitrectomy Study. Arch Ophthalmol 1995; 113:1479-96.
9. Sharma S, Jalali S, Adiraju MV, et al Sensitivity and predictability of vitreous cytology, biopsy, and membrane filter culture in endophthalmitis. Retina 1996;16:525-9.
10. Bauer AW, Kirby WMM, Sherris JC, et al Antibiotic susceptibility testing by a single disc method. Am J Clin Pathol 1966;45:493.
11. Han DP, Wisniewski SR, Wilson LA, et al and Endophthalmitis Study Group. Spectrum and susceptibility of microbiologic isolates in the Endophthalmitis Study Group. Am J Ophthalmol 1996;122:1-17.
12. Das T, Dogra MR, Gopal LJ, et al. Postsurgical endophthalmitis: diagnosis and management, Indian J Ophthalmol 1995;43:103-16.
13. Gardner S.Treatment of bacterial endophthalmitis. Part I. Ocular therapeutics and Management 1992;2:1.
14. Metrikin DC, Wilson CA, Berkowitz BA, et al. Measurement of blood-retinal barrier breakdown in endotoxin-induced endophthalmitis. Invest Ophthalmol Vis Sci 1995; 36:1361-70.
15. Jet BD, Jennies HG, Atkuri RV, et al. Evaluation of therapeutic measures for treating endophthalmitis caused by isogenic toxin producing and toxin-nonproducing Enterococcus faecalis strains. Invest Ophthalmol Vis Sci 1995;36: 9-15.
16. Booth MC, Atkuri RV, Nanda SK, et al. Accessory gene regulator controls Staphylococcus aureus virulence in endophthalmitis. Invest Ophthalmol Vis Sci 1995;36:1828-36.
17. Jacobs DR, Cohen HB. The inflammatory role of endotoxin in rabbit Gram-negative bacterial endophthalmitis. Invest Ophthalmol Vis Sci 1984;25:1074-9.
18. Baum J. Therapy for ocular bacterial infection. Trans Ophthalmol Soc UK 1986;105:69-77.
19. Bustros SD, Michels RG, Glaser BM. Evolving concepts in the management of posterior segment penetrating ocular injuries. Retina 1990;10(suppl):s72-5.
20. Charp AD. In: Tasman W, Jaeger EA, eds. Duane's foundations of clinical ophthalmology. Philadelphia: JB Lippincott, chapter 31:1:35.
21. Kwak HW, D'Amico DJ. Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection. Arch Ophthalmol 1992;110:259-66.
22. Smolin G, Tabbara K, Whitcher J. Infectious diseases of the eye. Baltimore: Williams and Wilkins, 1984:148-61.
23. Davey RJ, Tauber WB. Posttraumatic endophthalmitis: the emerging role of Bacillus cereus infection. Rev Infect Dis 1987;9:110-23.
24. Engstrom RE Jr, Mondino BJ, Glasgow BJ, et al. Immune response to Staphylococcus aureus endophthalmitis in a rabbit model. Invest Ophthalmol Vis Sci 1991;32:181-6.