Different mechanisms for the photoinduced production of oxidative dna damage by fluoroquinolones differing in photostability

Chemical Research in Toxicology

Volumn 12, Issue 9, 1999, Pages 809-815

  Spratt, Thomas E ^a   Schultz, Sherri S ^a   Levy, Douglas E ^a   Chen, Di ^a   Schlüter, Gerhardt ^b   Williams, Gary M ^a,c  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b BAYER AG   (Germany)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 1 CYCLOPROPYL 7 (2,8 DIAZABICYCLO[4.3.0]NON 8 YL) 6 FLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; CIPROFLOXACIN; LOMEFLOXACIN; MOXIFLOXACIN; OXYGEN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; REACTIVE OXYGEN METABOLITE;

ARTICLE; CARCINOGENICITY; DNA DAMAGE; ELECTROCHEMICAL ANALYSIS; GEL ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; PHOTOCHEMISTRY; THYMUS; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION;

ANIMALS; ANTI-INFECTIVE AGENTS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA DAMAGE; DRUG STABILITY; ELECTROPHORESIS, AGAR GEL; FLUOROQUINOLONES; OXIDATION-REDUCTION; PHOTOSENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

EID: 0032824922     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx980224j     Document Type: Article

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