Importance of biotransformation pathways for interpreting biological monitoring of exposure

Toxicology Letters

Volumn 108, Issue 2-3, 1999, Pages 91-97

  Lison, Dominique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Biomarker; Effect biomonitoring; Exposure biomonitoring; Interaction; Polycyclic aromatic hydrocarbons; Polymorphism; Speciation

Indexed keywords

BIOTRANSFORMATION; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DISEASE MARKER; GENETIC VARIABILITY; HUMAN; PRIORITY JOURNAL; REVIEW; TISSUE DISTRIBUTION; TOXICITY; TOXICITY TESTING; TOXICOKINETICS;

EID: 0032824004     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00077-6     Document Type: Article

References (15)

1. Altenkirch H., Wagner H.M., Stoltenburg-Didinger G., Steppat R. Potentiation of hexacarbon-neurotoxicity by methyl-ethyl-ketone (MEK) and other substances, clinical and experimental aspects. Neurobehav. Toxicol. Teratol. 4:1982;623-627.
2. Apostoli P. Element speciation in biological monitoring [editorial]. Int. Arch. Occup. Environ. Health. 69:1997;369-371.
3. Bernard A.M. Biokinetics and stability aspects, of biomarkers, recommendations for application in population studies. Toxicology. 101:1995;65-71.
4. Chen L., Mohr S.N., Yang C.S. Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers. Clin. Pharmacol. Ther. 60:1996;651-660.
5. Cocker J., Nutley B.P., Wilson H.K. A biological monitoring assessment of exposure to methylene dianiline in manufacturers and users. Occup. Environ. Med. 51:1994;519-522.
6. Finley B.L., Kerger B.D., Katona M.W., Gargas M.L., Corbett G.C., Paustenbach D.J. Human ingestion of chromium (VI) in drinking water, pharmacokinetics following repeated exposure. Toxicol. Appl. Pharmacol. 142:1997;151-159.
7. Gerde P., Muggenburg B.A., Scott G.G., Lewis J.L., Pyon K.H., Dahl A.R. Local metabolism m lung airways increases the uncertainty of pyrene as a biomarker of polycyclic aromatic hydrocarbon exposure. Carcinogenesis. 19:1998;493-500.
8. Haufroid V., Thirion F., Mertens P., Buchet J.-P., Lison D. Biological monitoring of workers exposed to low level of 2-butoxyethanol. Int. Arch. Occup. Environ. Health. 70:1997;232-237.
9. Hoet P., Haufroid V. Biological monitoring. State Art. Occup. Environ. Med. 54:1997;361-366.
10. Huang C.Y., Huang K.L., Cheng T.J., Wang J.D., Hsieh L.L. The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function. Arch. Toxicol. 71:1997;482-488.
11. Lison D., Buchet J.-P., Swennen B., Molders J., Lauwerys R. Biological monitoring of workers exposed to cobalt metal, salts, oxide and hard metal dust. Occup. Environ. Med. 51:1994;447-450.
12. Mortensen B., Zahlsen K., Nilsen O.G. Metabolic interaction of n-hexane and methyl ethyl ketone in vitro in a head space rat liver S9 vial equilibration system. Pharmacol. Toxicol. 82:1998;67-73.
13. Nelson H.H., Wiencke J.K, Christiani D.C., Cheng T.J., Zuo Z.F., Schwartz B.S., Lee B.K., Spitz M.R., Wang M., Xu X. et al. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis. 16:1995;1243-1245.
14. Rannug A., Alexandrie A.-K., Persson I., Ingelman-Sundberg M. Genetic polymorphism of cytochromes P450 1A1, 2D6 and 2E1, regulation and toxicological significance. J. Occup. Environ. Med. 37:1995;25-36.
15. van Engelen J.G., Rebel de Haan W., Opdam J.J., Mulder G.J. Effect of coexposure to methyl ethyl ketone (MEK) on n-hexane toxicokinetics in human volunteers. Toxicol. Appl. Pharmacol. 144:1997;385-395.