Neutrons expand the field of structural biology

Current Opinion in Structural Biology

Volumn 9, Issue 5, 1999, Pages 602-608

  Niimura, Nobuo ^a  

^a JAPAN ATOMIC ENERGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN; PROTEIN;

CHEMICAL STRUCTURE; CRYSTALLOGRAPHY; DIFFRACTION; HYDRATION; IMAGING; INFORMATION PROCESSING; MACROMOLECULE; NEUTRON; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW;

EID: 0032823529     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(99)00012-3     Document Type: Review

References (48)

1. Bentley GA, Duee ED, Mason SA, Nunes AC Protein structure determination by neutron diffraction: lysozyme. J Chim Phys. 76:1979;817-821.
2. Kossiakoff AA, Spencer SA Neutron diffraction identifies His-57 as the catalytic base in trypsin. Nature. 288:1980;414-416.
3. Phillips SEV, Schoenborn BP Neutron diffraction reveals oxygen-histidine hydrogen bond in oxymyoglobin. Nature. 292:1981;81-82.
4. Kossiakoff AA, Spencer SA Direct determination of protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin. Biochemistry. 20:1981;6462-6474.
5. Wlodawer A, Sjolin L Hydrogen exchange in RNase A: neutron diffraction study. Proc Natl Acad Sci USA. 79:1982;1418-1422.
6. Wlodawer A, Hendrickson WA A procedure for joint refinement of macromolecular structures with X-ray and neutron diffraction data from single crystals. Acta Crystallogr. A38:1982;239-247.
7. Wlodawer A, Miller M, Sjolin L Active site of RNase: neutron diffraction study of a complex with uridine vanadate, a transition-state analog. Proc Natl Acad Sci USA. 80:1983;3628-3631.
8. Wlodawer A, Walter J, Huber R, Sjolin L Structure of bovine pancreatic trypsin inhibitor - results of joint neutron and X-ray refinement of crystal form II. J Mol Biol. 180:1984;301-329.
9. Teeter MM, Kossiakoff AA The neutron structure of the hydrophobic plant protein crambin. Schoenborn BP, Knott RB Neutrons in Biology. 1984;335-348 Plenum Press, New York.
10. Kossiakoff AA The application of neutron crystallography to the study of dynamic and hydration properties of proteins. Annu Rev Biochem. 54:1985;1195-1227.
11. Lehmann MS, Mason SA, McIntyre GJ Study of ethanol-lysozyme interactions using neutron diffraction. Biochemistry. 24:1985;5862-5869.
12. Savage H, Wlodawer A Determination of water structure around biomolecules using X-ray and neutron diffraction methods. Methods Enzymol. 127:1986;162-183.
13. Wlodawer A, Borkakoti N, Moss DS, Howlin B Comparison of two independently refined models of RNase A. Acta Crystallogr. B42:1986;379-387.
14. Wlodawer A, Deisenhofer J, Huber R Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor. J Mol Biol. 193:1987;145-156.
15. Schoenborn BP Solvent effect in protein crystals - a neutron diffraction analysis of solvent and ion density. J Mol Biol. 201:1988;741-749.
16. Lehmann MS, Stansfield RFD Binding of dimethyl sulfoxide to lysozyme in crystals, studied with neutron diffraction. Biochemistry. 28:1989;7028-7033.
17. Wlodawer A, Savage H, Dodson G Structure of insulin: result of joint neutron and X-ray refinement. Acta Crystallogr. B45:1989;99-107.
18. Cheng X, Schoenborn BP Hydration in protein crystals. A neutron diffraction analysis of carbonmonoxymyoglobin. Acta Crystallogr. B46:1990;195-208.
19. Finer-Moore JS, Kossiakoff AA, Hurley JH, Earnest T, Stroud RM Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins. 12:1992;203-222.
20. 2O solvent maps: pattern of primary and secondary hydration of trypsin. Proteins. 12:1992;223-236.
21. Raghavan NV, Wlodawer A Neutron crystallography of proteins. Skold K, Price DL Methods of Experimental Physics. Volume 23, Part C, Neutron Scattering. 1987;335-365 Academic Press, Orlando, FL.
22. Niimura N, Minezaki Y, Nonaka T, Castagna JC, Cipriani F, Hoghoj P, Lehmann MS, Wilkinson C Neutron Laue diffractometry with an imaging plate provides an effective data collection regime for neutron protein crystallography. Nat Struct Biol. 4:1997;909-914. The first result of neutron Laue diffractometry with a neutron imaging plate. The positions of 960 hydrogen atoms and 157 bound water molecules in the hen egg-white lysozyme were determined.
23. Helliwell JR Neutron Laue diffraction does it faster. Nat Struct Biol. 4:1997;874-876.
24. Rausch C, Bücherl T, Gähler R, Seggern H, Winnacker A Recent developments in neutron detection. SPIE. 1737:1992;255-263.
25. Wilkinson C, Gabriel A, Lehmann MS, Zemb T, Né F Image plate neutron detector. SPIE. 1737:1992;324-329.
26. Niimura N, Karasawa Y, Tanaka I, Miyahara J, Takahashi K, Saito H, Koizumi S, Hidaka M An imaging plate neutron detector. Nucl Instrum Meth Phys Res A. 349:1994;521-525.
27. Cipriani F, Castagna JC, Lehmann MS, Wilkinson C A large image-plate detector for neutrons. Physica B. 213-214:1995;975-977.
28. Karasawa Y, Kumazawa S, Niimura N The character and application of a neutron imaging plate (NIP). Physica B. 241-243:1998;139-141.
29. Haga Y, Kumazawa S, Niimura N: Gamma-ray sensitivity and shielding of a neutron imaging plate. J Appl Crystallogr 1999, in press. One of the disadvantages of neutron imaging plates is that they are sensitive to gamma rays. This prevents their common usage. Methods for shielding a neutron imaging plate from gamma rays are proposed.
30. Wilkinson C, Lehmann MS Quasi-Laue neutron diffractometer. Nucl Instrum Meth Phys Res A. 310:1991;411-415.
31. Cipriani F, Castagna JC, Wilkinson C, Lehmann MS, Buldt G A neutron image plate quasi-Laue diffractometer for protein crystallography. Schoenborn BP, Knott RB Neutrons in Biology:1996;423-431 Plenum Press, New York.
32. Myles DAA, Bon C, Langan P, Cipriani F, Castagna JC, Lehmann MN, Wilkinson C Neutron Laue diffraction in macromolecular crystallography. Physica B. 241-243:1998;1122-1130. In this paper, recent examples of neutron Laue diffraction experiments on macromolecules are reviewed.
33. Wilson CC The potential for biological structure determination with pulsed neutrons. Schoenborn BP, Knott RB Neutrons in Biology. 1996;35-55 Plenum Press, New York.
34. Forsyth VT, Langan P, Whalley MA, Mahendrasingam A, Wilson CC, Giesen U, Dauvergne MT, Mason SA, Fuller W Time-of-flight Laue fiber diffraction studies of perdeuterated DNA. Schoenborn BP, Knott RB Neutrons in Biology. 1996;359-367 Plenum Press, New York.
35. Fuller W, Forsyth VT, Mahendrasingam A, Langan P, Pigram WJ, Mason SA, Wilson CC DNA hydration studied by neutron fiber diffraction. Schoenborn BP, Knott RB Neutrons in Biology. 1996;345-358 Plenum Press, New York.
36. Pope LH, Shotton MW, Forsyth VT, Langan P, Denny RC, Giesen U, Dauvergne MT, Fuller W Ordered water around deuterated A-DNA by neutron fibre diffraction. Physica B. 241-243:1998;1156-1161.
37. Shotton MW, Pope LH, Forsyth VT, Langan P, Grimm H, Rupprecht A, Denny RC, Fuller W A high-angle neutron fibre diffraction study of the hydration of B-DNA. Physica B. 241-243:1998;1166-1168.
38. Niimura N, Tanaka I, Minezaki Y, Karasawa Y, Tanaka I, Miki M, Sato M, Hidaka M, Minakawa N, Morii M Diffractometer for neutron crystallography in biology. Physica B. 213-214:1995;786-789.
39. Niimura N, Tanaka I, Karasawa Y, Minakawa N A monochromator for neutron crystallography in biology. Physica B. 213-214:1995;929-931.
40. Niimura N Neutron diffractometer for bio-crystallography (BIX) with an imaging plate neutron detector. Schoenborn BP, Knott RB Neutrons in Biology. 1996;415-422 Plenum Press, New York.
41. Tanaka I, Minezaki Y, Harada K, Niimura N Data acquisition of neutron crystallography on tetragonal and triclinic forms of hen-egg-white (HEW) lysozyme with an elastically bent Si monochromator. Physica B. 241-243:1998;227-230.
42. Tanaka I, Niimura N, Mikula P An elastically bent silicon monochromator for a neutron diffractometer. J Appl Crystallogr. 32:1999;525-529. The principles behind using an elastically bent silicon monochromator in a neutron diffractometer and the special bending device used to make it functional are discussed in this paper.
43. Fujiwara S, Karasawa Y, Tanaka I, Minezaki Y, Yonezawa Y, Niimura N A neutron diffractometer for biological macromolecules using neutron imaging plates. Physica B. 241-243:1998;207-209.
44. Shu F, Ramakrishnan V, Schoenborn BP: Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin. Proc Natl Acad Sci USA 1999, in press. The first result of a neutron protein diffraction experiment using fully deuterated myoglobin. The structure reveals a wealth of chemical information about the molecule, including the geometry of hydrogen bonds, the protonation states of histidines and the location and geometry of water molecules at the surface of the protein.
45. Conrad H The European spallation sources (ESS) technical study. Haines J, Taleyarkhan R 2nd International Topical Meeting on Nuclear Applications of Accelerator Technology. 1998;13-21 American Nuclear Society Inc, La Grange Park, Illinois.
46. Alonso JR The spallation neutron source (SNS) project: introduction. Haines J, Taleyarkhan R 2nd International Topical Meeting on Nuclear Applications of Accelerator Technology. 1998;197-201 American Nuclear Society Inc, La Grange Park, Illinois.
47. Mukaiyama T, Oyama Y, Mizumoto M, Takizuka T, Hino R Neutron science project at JAERI. Van Tuyle GJ Proceedings Topical Meeting on Nuclear Applications of Accelerator Technology. 1997;398-404 American Nuclear Society Inc, La Grange Park, Illinois.
48. Schoenborn BP, Court JD, Larson AC, Ferguson P Moderator decoupling options for structural biology at spallation neutron sources. J Neutron Res. 7:1999;89-106. A glimpse of the diffractometer that might be installed at the next generation neutron source for neutron structural biology.