Influence of training paradigm on specificity of drug mixture discriminations

Pharmacology Biochemistry and Behavior

Volumn 64, Issue 2, 1999, Pages 409-413

  Mariathasan, E A ^a   Stolerman, I P ^a   White, J A W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Amphetamine; Caffeine; Cocaine; Drug discrimination; Ethanol; Midazolam; Nicotine; Pentobarbitone; Rats

Indexed keywords

ALCOHOL; AMPHETAMINE; CAFFEINE; COCAINE; MIDAZOLAM; NICOTINE; PENTOBARBITAL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; DRUG MIXTURE; DRUG SPECIFICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; STIMULUS GENERALIZATION; SUBCUTANEOUS DRUG ADMINISTRATION; TRAINING;

ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DISCRIMINATION (PSYCHOLOGY); DISCRIMINATION LEARNING; DRUG COMBINATIONS; EXTINCTION, PSYCHOLOGICAL; GENERALIZATION, STIMULUS; HYPNOTICS AND SEDATIVES; MALE; PENTOBARBITAL; RATS;

EID: 0032822971     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(99)00088-X     Document Type: Conference Paper

References (15)

1. Clark D., Exner M., Furmidge L.J., Svensson K., Sonnesson C. Effects of the dopamine autoreceptor antagonist (-)-DS121 on the discriminative stimulus properties of d-amphetamine and cocaine. Eur. J. Pharmacol. 275:1995;67-74.
2. De Vry J., Slangen J.L. Differential interactions between chlordiazepoxide, pentobarbital and benzodiazepine antagonists Ro 15-1788 and CGS 8216 in a drug discrimination procedure. Pharmacol. Biochem. Behav. 24:1986;999-1005.
3. Garcha H.S., Stolerman I.P. Discrimination of a drug mixture in rats. Role of training dose, and specificity Behav. Pharmacol. 1:1989;25-31.
4. Garcha H.S., Rose I.C., Stolerman I.P. Midazolam cue in rats. Generalization tests with anxiolytics and other drugs Psychopharmacology (Berlin). 87:1985;233-237.
5. Gauvin D.V., Holloway F.A. The discriminative stimulus properties of an ethanol-nicotine mixture in rats. J. Psychopharmacol. 7:1993;52-62.
6. Gauvin D.V., Moore K.R., Youngblood B.D., Holloway F.A. The discriminative stimulus properties of legal, over-the-counter stimulants administered singly and in binary and ternary combinations. Psychopharmacology (Berlin). 110:1993;309-319.
7. Mariathasan E.A., Stolerman I.P. Functional relationships, previous history and the discrimination of a drug mixture in rats. Drug Alcohol Depend. 35:1994;117-125.
8. Mariathasan E.A., Garcha H.S., Stolerman I.P. Discriminative stimulus effects of amphetamine and pentobarbitone separately and as mixtures in rats. Behav. Pharmacol. 2:1991;405-415.
9. Mariathasan E.A., Stolerman I.P., White J.-A.W. Antagonism of AND and AND-OR drug mixture discrimination in rats. Drug Alcohol Depend. 44:1997;31-34.
10. Mariathasan E.A., Stolerman I.P., White J.W. AND and AND-OR drug mixture discriminations in rats. Generalization to single drugs and drug mixtures Psychopharmacology (Berlin). 143:1999;54-63.
11. Oka M., Yamada K., Yoshida K., Shimizu M. Avoidance enhancement and discriminative response control by anxiolytics with drugs acting on the GABA system. Jpn. J. Pharmacol. 30:1980;325-336.
12. Reavill C., Stolerman I.P. Interaction of nicotine with dopaminergic mechanisms assessed through drug discrimination and rotational behaviour in rats. J. Psychopharmacol. 1:1987;264-273.
13. Schechter M.D., Rosecrans J.A. d-Amphetamine as a discriminative cue. Drugs with similar stimulus properties Eur. J. Pharmacol. 21:1973;212-216.
14. Shoaib M., Baumann M.H., Roth B.L., Goldberg S.R., Schindler C.W. Behavioural and neurochemical characteristics of phentermine and fenfluramine administered separately and as a mixture in rats. Psychopharmacology (Berlin). 131:1997;296-306.
15. Stolerman I.P., D'Mello G.D. Role of training conditions in discrimination of central nervous system stimulants by rats. Psychopharmacology (Berlin). 73:1981;295-303.