Pyrimidine nucleobase ligands of orotate phosphoribosyltransferase from toxoplasma gondii

Biochemical Pharmacology

Volumn 58, Issue 9, 1999, Pages 1457-1466

  Javaid, Zahid Z ^a   El Kouni, Mahmoud H ^b   Iltzsch, Max H ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Orotate phosphoribosyltransferase; Pyrimidine nucleobases; Structure activity; Toxoplasma gondii

Indexed keywords

BARBITURIC ACID DERIVATIVE; OROTATE PHOSPHORIBOSYLTRANSFERASE; OROTIC ACID; OROTIC ACID DERIVATIVE; PYRIMIDINE NUCLEOSIDE DERIVATIVE; URACIL DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; ENZYME INHIBITION; HYDROGEN BOND; ION EXCHANGE CHROMATOGRAPHY; IONIZATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TOXOPLASMA GONDII;

ANIMALS; BINDING SITES; DRUG DESIGN; EVALUATION STUDIES; LIGANDS; MAMMALS; OROTATE PHOSPHORIBOSYLTRANSFERASE; OROTIC ACID; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TOXOPLASMA;

EID: 0032821898     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00231-2     Document Type: Article

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