Exposure of northern leopard frogs in the Green Bay ecosystem to polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans is measured by direct chemistry but not hepatic ethoxyresorufin-O-deethylase activity

Environmental Toxicology and Chemistry

Volumn 18, Issue 10, 1999, Pages 2123-2130

  Huang, Yue Wérn ^a,c   Karasov, William H ^a   Patnode, Kathleen A ^b   Jefcoate, Colin R ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b WISCONSIN DEPARTMENT OF NATURAL RESOURCES   (United States)

^c Michigan State University   (United States)

Author keywords

Biomarkers; Ethoxyresorufin O deethylase activity; Northern leopard frogs; Tissue toxicant residues

Indexed keywords

BIOLOGICAL MARKER; ETHOXYRESORUFIN DEETHYLASE; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT ASSESSMENT; ENZYME ACTIVITY; FROG; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; RIVER; WATER CONTAMINATION;

ANIMALIA; ANURA; CANIDAE; PANTHERA PARDUS; RANA PIPIENS; VERTEBRATA;

EID: 0032821701     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(1999)018<2123:EONLFI>2.3.CO;2     Document Type: Article

References (41)

1. Sullivan JR, Delffino JJ. 1982. A select inventory of chemicals used in Wisconsin's lower Fox River Basin. WIS-SG-82-238. University of Wisconsin Sea Grant Institute, Madison, WI, USA.
2. Kubiak TJ, et al. 1989. Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan -1983. Arch Environ Contam Toxicol 18:706-727.
3. Harris HJ. 1990. The State of the Bay: A Capsule View. University of Wisconsin-Green Bay, Institute for Land and Water Studies, Green Bay, WI, USA.
4. U.S. Environmental Protection Agency. 1989. Green Bay/Fox River mass balance study. EPA 905/8-89/001. Great Lakes National Program Office, Chicago, IL.
5. Gilbertson M, Fox GA. 1977. Pollutant-associated embryonic mortality of Great Lakes herring gulls. Environ Pollut 12:211-216.
6. Haseltine SD, Heinz GH, Reichel WL, Moore JF. 1981. Organochlorine and metal residues in eggs of waterfowl nesting in Lake Michigan of Door County, Wisconsin, 1977-78. Pestic Monit J 15:90-97.
7. Hoffman DJ, Rattner BA, Sileo L, Docherty D, Kubiak TJ. 1987. Embryotoxicity, teratogenicity, and aryl hydrocarbon hydroxylase activity in Forster's terns on Green Bay, Lake Michigan. Environ Res 42:176-184.
8. Dunson WA, Wyman RL. 1992. Symposium: Amphibian declines and habitat acidification. J Herpetol 26:349-442.
9. Korfmacher WA, Hansen EB Jr, Rowland KL. 1986. Tissue distribution of 2,3,7,8-TCDD in bullfrogs obtained from a 2,3,7,8-TCDD-contaminated area. Chemosphere 2:121-126.
10. Dowd PF, Mayfield GU, Coulon DP, Graves JB, Newsom J. 1985. Organochlorine residues in animals from three Louisiana watersheds in 1978-1979. Bull Environ Contam Toxicol 34:832-841.
11. Beatty PW, Holscher MA, Neal RA. 1976. Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in larval and adult forms of Rana catesbeiana. Bull Environ Contam Toxicol 16:578-581.
12. Peakall D. 1992. Animal Biomarkers as Pollution Indicators, 1st ed. Chapman & Hall, New York, NY, USA.
13. Payne JF, Fancey LL, Rahimtula AD, Porter EL. 1987. Review and perspective on the use of mixed-function oxygenase enzymes in biological monitoring. Comp Biochem Physiol 86:233-245.
14. Stegeman JJ, Brouwer M, DiGiulio RT, Forlin L, Fowler BM, Sander BM, Van Veld P. 1992. Molecular responses to environmental contamination: Enzyme and protein systems as indicators of contaminant exposure and effect. In Huggett RJ, ed, Biomarkers for Chemical Contaminants. CRC, Boca Raton, FL, USA, pp 237-339.
15. Goksoyr A, Forlin L. 1992. The cytochrome P450 system in fish, aquatic toxicology and environmental monitoring. Aquat Toxicol 22:287-312.
16. Harris ML, Bishop CA, Struger J, van den Heuvel MR, van der Kraak GJ, Dixson DG, Ripley B, Bogart JP. 1998. The functional integrity of northern leopard frog (Rana pipiens) and green frogs (Rana clamitans) populations in orchard wetlands. I. Genetics, physiology, and biochemistry of breeding adults and young-of-the-year. Environ Toxicol Chem 17:1338-1350.
17. Huang YW, Melancon MJ, Jung RE, Karasov WH. 1998. Induction of cytochrome P450-associated monooxygenases in northern leopard frogs, Rana pipiens, by 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126). Environ Toxicol Chem 17:1564-1569.
18. U.S. Environmental Protection Agency. 1983. Final report of the toxic substances task forces on the lower Fox River System. Great Lakes National Program Office, Chicago, IL.
19. Zabel EW, Cook PM, Peterson RE. 1995. Toxic equivalency factors of polychlorinated dibenzo-p-dioxin, dibenzofuran and biphenyl congeners based on early life stage mortality in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol 31:315-328.
20. Rabovsky J, Judy DJ, Sapola NA, Pailes WH, McPeek M, Castranova V. 1989. Cytochrome P450-dependent alkoxyphenoxazone dealkylase activity in rat alveolar type II cells: Effect of pretreatment with β-naphthoflavone. Cell Biochem Fund 7:79-89.
21. Brown R, Jarvis K, Hyland K. 1989. Protein measurement using bicinchoninic acid: Elimination of interference substance. Anal Biochem 180:136-139.
22. Huang YW. 1998. Exposure of northern leopard frogs to PCB 126, an aryl hydrocarbon receptor agonist: Direct chemistry, biochemical markers, and toxicokinetics. PhD thesis. University of Wisconsin, Madison, WI, USA.
23. Wisconsin State Laboratory of Hygiene. 1994. Method 1410 of the organic chemistry of the WSLOH. University of Wisconsin, Madison, WI, USA.
24. Jung RE. 1996. The potential influence of environmental pollution on amphibian development and decline. PhD thesis. University of Wisconsin, Madison, WI, USA.
25. House LB. 1990. Data on polychlorinated biphenyls, dieldrin, lead, and cadmium in Wisconsin and Upper Michigan tributaries to Green Bay, July 1987 through April 1988. Open-File Report 89-52. U.S. Department of the Interior Geological Survey, Madison, WI.
26. House LB. 1995. Distribution and transport of polychlorinated biphenyls in Little Lake Butte des Morts, Fox River, Wisconsin, April 1987-October 1988. Open File Report 93-31. U.S. Department of the Interior Geological Survey, Madison, WI.
27. House LB, Hughes PE, Waschbusch RJ. 1993. Concentrations and loads of polychlorinated biphenyls in major tributaries entering Green Bay, Lake Michigan, 1989. Open File Report 93-132. U.S. Department of the Interior Geological Survey, Madison, WI.
28. Palmer KA, Harris HJ, Swackhamer DL. 1994. PCB levels in sediments, aquatic emergent insects, and marsh wrens in a Great Lakes coastal marsh. Proceedings, 2nd Annual Midwest Chapter Meeting, Society of Environmental Toxicology and Chemistry, La Crosse, WI, USA, March 3-4, 1994.
29. Custer CM, Custer TW, Allen PD, Stromborg K, Melancon MJ. 1998. Reproduction and environmental contamination in tree swallows nestling in the Fox River drainage and Green Bay, Wisconsin, USA. Environ Toxicol Chem 17:1786-1798.
30. Safe S. 1990. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21:51-88.
31. Kennedy SW, Lorenzen A, Jones SP, Hahn ME, Stegeman JJ. 1996. Cytochrome P4501A induction in avian hepatocyte cultures: A promising approach for predicting the sensitivity of avian species to toxic effects of halogenated aromatic hydrocarbons. Toxicol Appl Pharmacol 141:214-230.
32. Lorenzana RM, Hedstrom OR, Buhler DR. 1988. Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri). Toxicol Appl Pharmacol 96:159-167.
33. Rattner BA, et al. 1993. Biomonitoring environmental contamination with pipping black-crowned night heron embryos: Induction of cytochrome P450. Environ Toxicol Chem 8:1093-1102.
34. Melancon MJ, Lech JJ. 1983. Dose-effect relationship for induction of hepatic monooxygenase activity in rainbow trout and carp by Aroclor 1254. Aquat Toxicol 4:51-61.
35. Peterson RE, Theobald HM, Kimmel GL. 1993. Developmental and reproductive toxicity of dioxins and related compounds: Cross-species comparisons. Crit Rev Toxicol 23:283-335.
36. Besselink HT, Denison MS, Hahn ME, Karchner SI, Vethaak AD, Koeman JH, Brouwer A. 1998. Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): Characterization of the Ah receptor and the role of CYP1A inhibition. Toxicol Sci 43:161-171.
37. Hahn ME, Woodin BR, Stegeman JJ, Tillitt DE. 1998. Aryl hydrocarbon receptor function in early vertebrates: Inducibility of cytochrome P4501A in agnathan and elasmobranch fish. Comp Biochem Physiol 120:67-75.
38. Stegeman JJ, Hahn ME. 1994. Biochemistry and molecular biology of monooxygenases: Current perspectives on forms, functions, and regulation of cytochrome P450 in aquatic species. In Malins DC, Ostrander GK, eds, Aquatic Toxicology - Molecular, Biochemical, and Cellular Perspective. CRC, Boca Raton, FL, USA, pp 87-206.
39. Guiney PD, Smolowitz RM, Peterson RE, Stegeman JJ. 1997. Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in vascular endothelium with toxicity in early life stages of lake trout. Toxicol Appl Pharmacol 143:256-273.
40. Jung RE, Walker MK. 1997. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on development of anuran amphibians. Environ Toxicol Chem 16:230-240.
41. Beatty PW, Holscher MA, Neal RA. 1976. Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in larval and adult forms of Rana catesbeiana. Bull Environ Contam Toxicol 16:578-581.