Activity of the combination of nelfinavir and saquinavir against human immunodeficiency virus after failure of prior protease inhibitor therapy

Clinical Infectious Diseases

Volumn 29, Issue 3, 1999, Pages 702-703

  Kravcik, Stephen ^a   Victor, Gary ^a   Angel, Jonathan B ^a   Badley, Andrew D ^a   Garber, Gary E ^a   Cameron, D William ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; DELAVIRDINE; DIDANOSINE; INDINAVIR; LAMIVUDINE; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL ARTICLE; DRUG EFFICACY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; PRIORITY JOURNAL; SALVAGE THERAPY; TREATMENT FAILURE; VIRUS INHIBITION; VIRUS LOAD;

EID: 0032821583     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/598671     Document Type: Article

References (6)

1. Tebas P, Patrick AK, Kane EM, et al. Virologic responses to a ritonavir-saquinavir-containing regimen in patients who had previously failed nelfinavir, AIDS 1999;13:F23-8.
2. Gallicano K, Sahai J, Kravcik S, Seguin I, Bristow N, Cameron DW. Nelfinavir increases plasma exposure to saquinavir in hard gel capsule in HIV+ patients [abstract no 353]. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections (Chicago), Alexandria, VA: foundation for Retroviruses, and Human Health, 1998:145.
3. Bodsworth NJ, Slade MA, Ewan J, McNally L. Ritonavir and indinavir therapy at 28 weeks after 32 weeks' saquinavir therapy: influence of HIV-1 protease mutations [abstract no 396]. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections (Chicago), Alexandria, VA: Foundation for Retroviruses and Human Health, 1998:153.
4. Gallant JE, Barnett C, Raines C. Efficacy and durability of ritonavir/saquinavir as salvage therapy after failure of initial protease inhibitor regimen [abstract no 12330]. In: Conference record of the 12th World AIDS Conference. Geneva: Marathon Multimedia, 1998.
5. Cox SR, Schneck DW, Herman BD, et al. Delavirdine and nelfinavir: a pharmacokinetic drug-drug interaction study in healthy adult volunteers [abstract no 345]. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections (Chicago), Alexandria, VA: Foundation for Retroviruses and Human Health, 1998:153.
6. Kirk O, Katzenstein TL, Gerstoft J, et al. Combination therapy containing ritonavir plus saquinavir has superior short-term antiviral efficacy: a randomized study. AIDS 1999;13:F9-16.