Pharmacokinetics of moxidectin and doramectin in goats

Research in Veterinary Science

Volumn 67, Issue 2, 1999, Pages 177-181

  Escudero, E ^a   Carceles, C M ^a   Diaz, M S ^a   Sutra, J F ^b   Galtier, P ^b   Alvinerie, M ^b  

^a UNIVERSITY OF MURCIA   (Spain)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DORAMECTIN; MOXIDECTIN;

ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG RESISTANCE; GOAT; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; SUBCUTANEOUS DRUG ADMINISTRATION; VETERINARY MEDICINE;

ANIMALIA; CAPRA HIRCUS;

EID: 0032819516     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1053/rvsc.1998.0304     Document Type: Article

References (26)

1. ALVINERIE, M., SUTRA, J.F. & GALTIER, P. (1993) Ivermectin in goat plasma and milk after subcutaneous injection. Annales des Recherches Vétérinaires 24, 417-421.
2. ALVINERIE, M., SUTRA, J.F., TARDIEU, D., BOJENSEN, G. & GALTIER, P. (1994) Metabolic profile of ivermectin in goats: an in vivo and in vitro evaluation. Proceedings of the 6th European Association for Veterinary Pharmacology and Toxicology International Congress. Edinburgh, U.K. Blackwell Scientific Publications, Oxford, pp 262.
3. ALVINERIE, M., SUTRA, J.F., BADRI, M. & GALTIER, P. (1995) Determination of moxidectin in plasma by high-performance liquid chromatography with automated solid-phase extraction and fluorescence detection. Journal of Chromatography B, 674, 119-124.
4. ALVINERIE, M., SUTRA, J.F. LANUSSE, C. & GALTIER, P. (1996) Plasma profile study of moxidectin in a cow and its suckling calf. Veterinary Research 27, 545-549.
5. ALVINERIE, M. and GALTIER, P. (1997) Comparative pharmacokinetic properties of moxidectin and ivermectin in different animal species. Proceedings of the 7th European Association for Veterinary Pharmacology and Toxicology International Congress. Journal of Veterinary Pharmacology and Therapeutics 20 (suppl 1), 74.
6. ALVINERIE, M., ESCUDERO, E., SUTRA, J.F., EECKHOUTTE, C. & GALTIER, P. (1998) The pharmacokinetics of moxidectin after oral and subcutaneous administration to sheep. Veterinary Research 29, 113-118.
7. ANON (1991) Cydectin New Generation Endectocide Technical Manual. Cyanamid of New Zealand Limited. p 12.
8. BOGAN, J., BENOIT, E. & DELATOUR, P. (1987) Pharmacokinetics of oxfendazole in goats: a comparison with sheep. Journal of Veterinary Pharmacology and Therapeutics 10, 305-309.
9. ESCUDERO, E., CARCELES, C.M., GALTIER, P. & ALVINERIE, M. (1997) Influence of fasting on the pharmacokinetics of ivermectin in goats. Proceedings of the 7th European Association for Veterinary Pharmacology and Toxicology International Congress. Journal of Veterinary Pharmacology and Therapeutics 20 (suppl 1), 71-72.
10. GALTIER, P., ESCOULA, L., CAMGUILHEM, R. & ALVINERIE, M. (1981) Comparative bioavailability of levamisol in non lactating ewes and goats. Annales des Recherches Vétérinaires 12, 109-115.
11. GIBALDI, M. & PERRIER, D. (1982) Pharmacokinetics. 2nd edn. New York. Marcel and Dekker. pp 445-449.
12. GOUDI, A.C., EVANS, N.A., GRATION, K.A.F., BISHOP, B.F, GIBSON, S.P., HOLDOM, K.S., KAYE, B., WICKS, S.R., LEWIS, D., WEATHERLEY, A.J., BRUCE, C.I., HERBERT, A. & SEYMOUR, D.J. (1993) Doramectin - a potent novel endectocide. Veterinary Parasitology 49, 5-15.
13. JACKSON, F. JACKSON, E. & COOP, R.L. (1992) Evidence of multiple anthelmintic resistence in a strain of Teladorsagia circumcincta (Ostertagia circumcincta) isolated from goats in Scotland. Research in Veterinary Science 53, 371-374.
14. LANUSSE, C., LIFSCHITZ, A., VIRKEL, G., ALVAREZ, L., SÁNCHEZ, S., SUTRA, J.F., GALTIER, P. & ALVINERIE, M. (1997) Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics 20, 91-99.
15. LEATHWICK, D.M. (1995) A case of moxidectin failing to control ivermectin resistence Ostertagia species in goats. Veterinary Record 136, 443-444.
16. MARRINER, S.E., MCKINON, I & BOGAN, J.A. (1987) The pharmacokinetics of ivermectin after oral and subcutaneous administration to sheep and horses. Journal of Veterinary Pharmacology and Therapeutics 10, 175-179.
17. MCKELLAR, Q.A. & BENCHAOUI, H. (1996) Avermectins and milbemycins. Journal of Veterinary Pharmacology and Therapeutics 19, 331-351.
18. NOWAKOWSKI, M.A., LYNCH, M.J., SMITH, D.G., LOGAN, N.B., MOUZIN, D.E., LUKASZEWICZ, J., RYAN, N.I., HUNTER, R.P. & JONES, R.M. (1995) Pharmacokinetics and bioequivalence of parenterally administered doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics 18, 290-298.
19. OUKESSOU, M., SUTRA, J.F., GALTIER, P. & ALVINERIE, M. (1997) Plasma and milk pharmacokinetics of moxidectin in the camel (Camelus dromedarios). Proceedings of the 7th European Association for Veterinary Pharmacology and Toxicology International Congress. Journal of Veterinary Pharmacology and Therapeutics 20 (suppl 1), 81.
20. POWERS, J. (1990) Statistical analysis of pharmacokinetic data. Journal of Veterinary Pharmacology and Therapeutics 13, 113-120.
21. SCOTT, E.W., KINABO, L.D. & MCKELLAR, Q.A. (1990) Pharmacokinetics of ivermectin after oral or percutaneous administration to adult milking goats. Journal of Veterinary Pharmacology and Therapeutics 13, 432-435.
22. SHOOP, W.L., MICHAEL, B.F., HAINES, H.W., MURPHY, T.P., FAIDLEY, T.D., HAJDU, R. & THOMPSON, D.R. (1997) Moxidectin and ivermectin in lambs: plasma cepletion and efficacy against helminths. Proceedings of the 7th European Association for Veterinary Pharmacology and Toxicology International Congress. Journal of Veterinary Pharmacology and Therapeutis 20 (suppl 1), 12-14.
23. SHUMAKER, R.C. (1986) PKCALC: A basic interactive computer program for statistical and pharmacokinetic analysis of data. Drug metabolism Reviews 17, 331-348.
24. WATSON, T.G., HOSKING, B.C., LEATHWICK, D.M. & MCKEE, P.F. (1996) Ivermectin-moxidectin side resistence by Ostertagia species isolated from goats and passaged to sheep. Veterinary Record 138, 472-173.
25. YAMAOKA, K., NAKAGAWA, T. & UNO, T. (1978) Application of Akaike's Information Criterion (AIC) in the evaluation of linear pharmacokinetic equations. Journal of Pharmacokinetics and Biopharmaceutics 6, 165-175.
26. YAMAOKA, K., TAMIGAWARA, Y. NAKAGAWA, T. & UNO, T. (1981) A pharmacokinetic analysis program (MULTI) for microcomputer. Journal of Pharmacobio-Dynamics 4, 879-885.