Dexamethasone induced alterations in the levels of proteases involved in blood pressure homeostasis and blood coagulation in rats

Molecular and Cellular Biochemistry

Volumn 197, Issue 1-2, 1999, Pages 203-208

  Rajashree, Sampath ^a   Puvanakrishnan, Rengarajulu ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

ACE kallikrein; Aminopeptidase; Dexamethasone; Mean arterial pressure; Plasmin; Thrombin

Indexed keywords

AMINOPEPTIDASE; ARGININE CARBOXYPEPTIDASE; CYTOSOL AMINOPEPTIDASE; DEXAMETHASONE; DIPEPTIDYL CARBOXYPEPTIDASE; KALLIKREIN; PLASMIN; PROTEINASE; THROMBIN; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; ENZYME BLOOD LEVEL; HEART; HOMEOSTASIS; HYPERTENSION; KIDNEY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PATHOGENESIS; RAT; TISSUE LEVEL;

ANIMALS; BLOOD COAGULATION; BLOOD PRESSURE; DEXAMETHASONE; ENDOPEPTIDASES; HOMEOSTASIS; MALE; RATS; RATS, WISTAR;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0032819397     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006991009036     Document Type: Article

References (39)

1. Mantero F, Boscaro M: Glucocorticold dependent hypertension. J S Steroid Biochem Mol Biol 43: 409-413, 1992
2. Kaplan NM: Cushing's syndrome and congenital adrenal hyperplasia. In: NM Kaplan (ed). Clinical Hypertension, Baltimore: Williams and Wilkins, 1990, pp. 386-395
3. Garcia LJ, Fortes ZB, Samomiya P, Farsky SP: Insulin, glucocorticolds and the control of inflammatory responses. Agents Actions suppl 36: 99-118, 1992
4. Aoyagi T, Wada T, Kojima F, Nagai M, Harada S, Takeuchi T: Serum protease changes in spontaneously hypertensive rats. Contrast with those in essential hypertension in man. J Clin Biochem Nutr 10: 35-40, 1991
5. Nolly H, Carbini LA, Scicli G, Carretero OA, Scicli AG: A local kallikrein-kinin system is present in rat hearts. Hypertension 23: 919-923, 1994
6. Margollus HS: Tissue kallikrein and kinins. Regulation and roles in hypertension and diabetic diseases. Annu Rev Pharmacol Toxicol 29: 343-364, 1989
7. Wang C, Chao L, Chao J: Direct gene delivery of human tissue kallikrein reduces blood pressure in SHR. J Clin Invest 95: 1710-1716, 1995
8. Fishel RS, Eisenberg S, Shai SY, Redden RA, Bemstein K, Berk BC: Glucocorticolds induce angiotensin converting enzyme expression in vascular smooth muscle. Hypertension 25: 343-349, 1995
9. Rapp P, Dennis LS, McPartland RP, Batten L: Hormonal effects on kallikrein, esterase A2 and their inhibitors in rat urine. Endocrinology 114: 951-956, 1984
10. Stefanovic V, Vlahovic P, Ardaillou N, Ardaillou R: Receptor mediated induction of aminopeptidase A of human glomerular epithelial cells by glucocorticoids. FEBS Lett 294: 171-174, 1991
11. Van Giezen JJJ, Jansen JWCM: Inhibition of fibrinolytic activity in vivo by Dex is counterbalanced by an inhibition of platelet aggregation. Thromb Hemostasis 68: 69-73, 1992
12. Nasjletti A, Erman A, Cagen LM, Baer PG: Plasma concentrations renal excretion and tissue release of prostaglandin in the rat with dexamethasone induced hypertension. Endocrinology 114: 1033-1040, 1984
13. Rajashree S, Puvanakrishnan R: Alterations in certain lysosomal glycohydrolases and cathepsins in rats on dexamethasone administration. Mol Cell Biochem 154: 165-170, 1996
14. Hayakari M, Kondo Y, Izumi H: A rapid and simple spectrophotometric assay of angiotensin converting enzyme. Anal Biochem 84: 361-369, 1978
15. Aoyagi T, Wada T, Kojima F, Nagai M, Umezawa H: Various enzyme activities in muscle and other organs of dystrophic mice. J Clin Invest 67: 51-59, 1981
16. Morita T, Kato H, Iwanaga S, Takada K, Kimura T, Sakaldbara S: New fluorogenic substrates for thrombin, factor Xa, kallikreins and urokinase. J Biochem 82: 1495-1498, 1977
17. Kato H, Adachi N, Ohno Y, Iwanaga S, Takada K, Sakaldbara S: New fluorogenic peptide substrates for plasmin. J Biochem 88: 183-190, 1980
18. Lowry OH, Rosebrough NJ, Farr AL, Randal RJ: Protein measurement with the Polin phenol reagent. J Biol Chem 193: 265-275, 1951
19. Carretero OA, Scicli AG: The glandular kallikrein kinin system in hypertension. In: Sambht MP (ed). Fundamental fault in hypertension, Boston: Martinus Nyhoff publishers, 1984, pp. 158-174
20. Ito K: Glucocorticoid dependent kallikrein inhibitor in rat kidney. Chiba Igaku Zasshi 63: 197-203, 1987
21. Margollus HS, Horwitz D, Pisano JJ, Kelser HR: Urinary kallikrein excretion in hypertensive man. Relationship to sodium intake and sodium retaining steroids. Circ Res 35: 820-825, 1974
22. Zinner SH, Margollus HS, Rosner B, Kass EH: Stability of blood pressure rank and urinary kallikrein concentrations in childhood an eight year follow up. Circulation 58: 908-915, 1978
23. Berry TD, Hasstedt SJ, Hunt SC, Wu LL, Smith JB, Ash KO, Kuida H, Williams RR: A gene for high urinary kallikrein may protect against hypertension in Utah kindreds. Hypertension (Dallas) 13: 3-8, 1989
24. Ader JL, Pollock DNL Butterfield MI, Arendshorst: Abnormalities in kallikrein excretion in SHR. Am J Physiol 248: F396-F403, 1985
25. Argent NB, Wilkinson R, Baylis PH: Local hormones in the kidney: Protectors of the kidney against the body? J Endocrinol 126: 351-354, 1990
26. Dalakos TG, Elias AN, Anderson GR Streeten DHP, Schroeder ET: Evidence for an angiotensinogenic mechanism of the hypertension is Cushing's syndrome. J Clin Endocrinol Metab 46: 114-118, 1978
27. Dasarathy Y, Lanzillo JJ, Fanburg BL: Stimulation of bovine pulmonary artery endothelial cell ACE by dexamethasone: Involvement of steroid receptors. Am J Physiol 263: L645-L649, 1992
28. Stov K, Fenger- Gron, Mulvany MJ: Effects of angiotensin inhibitor, a calcium antagonist and an endothelin receptor antagonist on renal afferent arteriolar structure. Hypertension 28: 464-471, 1996
29. Becker RHA, Linz W, Scholkens BA: Pharmacological interference with the cardiac Renin-angiotensin system. J Cardiovasc Pharmacol 14: S10-S15, 1989
30. Geisterfer AAT, Peach MJ, Owens GK: Angiotensin II induces hypertrophy, not hyperplasia of cultured rat aortic smooth muscle cells. Circ Res 62: 749-756, 1988
31. Powell JS, Clozel J, Muller RKM, Kuhn H, Heffi F, Hosang M, Bawngartner HR: Inhibitors of ACE prevent myointimal proliferation after vascular injury. Science 245: 186-188, 1989
32. Zambetis Bellesis M, Dusting GJ, Mendelsohn FA, Richardson K: Autoradiographic localization of ACE and ang II binding sites in early atheroma like lesion in rabbit arteries. Clin Exp Pharmacol Physiol 18: 337-340, 1991
33. Asai K, Funald C, Hayashi T, Yamada K, Naito M, Kuzuya M, Yoshida F, Yoshimine N, Kuzuya F: Dexamethasone-induced suppression of aortic atherosclerosis in cholesterol fed rabbits. Arteriosclerosis and Thrombosis 13: 892-899, 1993
34. Wright JW, Mizutani S, Murray CE, Amir HZ, Harding JW: Aminopeptidase induced elevations and reductions in blood pressure in the SHR. J Hypertens 8: 969-974, 1990
35. Umegaki K, Inoue Y, Tomita T: The appearance of "exhausted" platelets at the time of stroke in stroke prone SHR. Thromb Hemostasis 54: 764-767, 1985
36. Umegaki K, Saegusa H, Kurokawa M, Ichikawa T: Effects of vitamin E administration on platelet function and serum lipid peroxides in DOCA -Salt hypertensive rats. Thromb Hemostasis 65: 411-414, 1991
37. Szczepanski M, Staff-Ziehnska: Fibrinolytic activity in thrombin infused rabbits. Thrombosis Research 39: 127-131, 1985
38. Beller FK, Mitchell PS, Gorstein F: Fibrin deposition in the rabbit kidney produced by protease inhibitors. Thromb Diathes Haemorrh 17: 427-439, 1967
39. Comp PC, Jacocks RM, Ferrell GL, Esmon CT: Activation of protein C in vivo. J Clin Invest 70: 127-134, 1982