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Volumn 26, Issue 1, 1999, Pages 20-28

Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBPI) mutation and loss in renal-cell carcinoma development

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARCINOGENESIS; DNA SEQUENCE; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; GENE LOSS; GENE MUTATION; GENE ORDER; GENE STRUCTURE; GENETIC POLYMORPHISM; GENETIC RISK; HETEROZYGOSITY LOSS; HUMAN; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TUMOR SUPPRESSOR GENE;

EID: 0032819302     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199909)26:1<20::AID-GCC3>3.0.CO;2-6     Document Type: Article
Times cited : (20)

References (38)
  • 1
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird AP. 1986. CpG-rich islands and the function of DNA methylation. Nature 321:209-213.
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 2
    • 0031259797 scopus 로고    scopus 로고
    • Characterization of the gene (YBP1) and transcript for the von Hippel-Lindau binding protein and isolation of the highly conserved murine homologue
    • Brinke A, Green PM, Gianelli F. 1997. Characterization of the gene (YBP1) and transcript for the von Hippel-Lindau binding protein and isolation of the highly conserved murine homologue. Genomics 45:105-112.
    • (1997) Genomics , vol.45 , pp. 105-112
    • Brinke, A.1    Green, P.M.2    Gianelli, F.3
  • 3
    • 0031776704 scopus 로고    scopus 로고
    • Inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: Evidence for a VHL-independent pathway in clear cell renal tumorigenesis
    • Clifford SC, Prowse AH, Affara NA, Buys CHCM. Maher ER. 1998. Inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumorigenesis. Genes Chromosomes Cancer 22:200-209.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 200-209
    • Clifford, S.C.1    Prowse, A.H.2    Affara, N.A.3    Buys, C.H.C.M.4    Maher, E.R.5
  • 6
    • 0030662273 scopus 로고    scopus 로고
    • Human cancer syndromes: Clues to the origin and nature of cancer
    • Fearon ER. 1997. Human cancer syndromes: clues to the origin and nature of cancer. Science 278:1043-1050.
    • (1997) Science , vol.278 , pp. 1043-1050
    • Fearon, E.R.1
  • 12
    • 0031967883 scopus 로고    scopus 로고
    • Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades
    • Ichimura K, Schmidt EE, Miyakawa A, Goike HM, Collins VP. 1998. Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades. Genes Chromosomes Cancer 22:9-15.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 9-15
    • Ichimura, K.1    Schmidt, E.E.2    Miyakawa, A.3    Goike, H.M.4    Collins, V.P.5
  • 13
    • 0002269844 scopus 로고    scopus 로고
    • Construction of bacterial artificial chromosome libraries using the modified P1 (PAC) system
    • Dracopoli, et al., editors New York: John Wiley and Sons
    • Ioannou PA, de Jong PJ. 1996. Construction of bacterial artificial chromosome libraries using the modified P1 (PAC) system. In Dracopoli, et al., editors. Current protocols in human genetics, unit 5.15. New York: John Wiley and Sons.
    • (1996) Current Protocols in Human Genetics, Unit 5.15
    • Ioannou, P.A.1    De Jong, P.J.2
  • 14
    • 0029147430 scopus 로고
    • Binding of the von Hippel-Lindau tumor-suppressor protein to Elongin-B and Elongin-C
    • Kibel A, Iliopoulos O, Decaprio JA, Kaelin WG. 1995. Binding of the von Hippel-Lindau tumor-suppressor protein to Elongin-B and Elongin-C. Science 269:1444-1446.
    • (1995) Science , vol.269 , pp. 1444-1446
    • Kibel, A.1    Iliopoulos, O.2    Decaprio, J.A.3    Kaelin, W.G.4
  • 15
    • 0029953780 scopus 로고    scopus 로고
    • Cul-1 is required for cell-cycle exit in C.elegans and identifies a novel gene family
    • Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock LM. 1996. Cul-1 is required for cell-cycle exit in C.elegans and identifies a novel gene family. Cell 85:829-839.
    • (1996) Cell , vol.85 , pp. 829-839
    • Kipreos, E.T.1    Lander, L.E.2    Wing, J.P.3    He, W.W.4    Hedgecock, L.M.5
  • 16
    • 0032518924 scopus 로고    scopus 로고
    • Structural and functional evidence for the presence of tumor suppressor genes on the short arm of chromosome 10 in human gliomas
    • Kon H, Sonoda Y, Kumabe T. Yoshimoto T, Sekiya T, Murakami Y. 1998. Structural and functional evidence for the presence of tumor suppressor genes on the short arm of chromosome 10 in human gliomas. Oncogene 16:257-263.
    • (1998) Oncogene , vol.16 , pp. 257-263
    • Kon, H.1    Sonoda, Y.2    Kumabe, T.3    Yoshimoto, T.4    Sekiya, T.5    Murakami, Y.6
  • 18
    • 0029795584 scopus 로고    scopus 로고
    • Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein
    • Levy AP, Levy NS, Goldberg MA. 1996. Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein. J Biol Chem 271:25492-25497.
    • (1996) J Biol Chem , vol.271 , pp. 25492-25497
    • Levy, A.P.1    Levy, N.S.2    Goldberg, M.A.3
  • 19
    • 0031907152 scopus 로고    scopus 로고
    • Regulation of hypoxia mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongin B/C and Cul2
    • Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG. 1998. Regulation of hypoxia mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongin B/C and Cul2. Mol. Cell. Biol. 18:732-741.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 732-741
    • Lonergan, K.M.1    Iliopoulos, O.2    Ohh, M.3    Kamura, T.4    Conaway, R.C.5    Conaway, J.W.6    Kaelin, W.G.7
  • 20
    • 0031445126 scopus 로고    scopus 로고
    • von Hippel-Lindau disease
    • Maher ER, Kaelin WG. 1997. von Hippel-Lindau disease. Medicine 76:381-391.
    • (1997) Medicine , vol.76 , pp. 381-391
    • Maher, E.R.1    Kaelin, W.G.2
  • 21
    • 0029900642 scopus 로고    scopus 로고
    • Practical methods of mutation detection
    • Mashal RD, Sklar J. 1996. Practical methods of mutation detection. Curr Op Genet Devel 6:275-280.
    • (1996) Curr Op Genet Devel , vol.6 , pp. 275-280
    • Mashal, R.D.1    Sklar, J.2
  • 22
    • 0029011539 scopus 로고
    • 5' CpG island methylation is associated with transcriptional silencing of the tumor-suppressor P16/Cdkn2/Mts1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D. 1995. 5' CpG island methylation is associated with transcriptional silencing of the tumor-suppressor P16/Cdkn2/Mts1 in human cancers. Nat Med 1:686-692.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 24
    • 0024595101 scopus 로고
    • Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
    • Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T. 1989. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Nad Acad Sci USA 86:2766-2770.
    • (1989) Proc Nad Acad Sci USA , vol.86 , pp. 2766-2770
    • Orita, M.1    Iwahana, H.2    Kanazawa, H.3    Hayashi, K.4    Sekiya, T.5
  • 25
    • 0030953635 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
    • Pause A, Lee S, Worrel RA, Chen DYT, Burgess WH, Linehan WM, Klausner RD. 1997. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Natl Acad Sci USA 94:2156-2161.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2156-2161
    • Pause, A.1    Lee, S.2    Worrel, R.A.3    Chen, D.Y.T.4    Burgess, W.H.5    Linehan, W.M.6    Klausner, R.D.7
  • 26
    • 0032477788 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal
    • Pause A, Lee S, Lonergan KM, Klausner RD. 1998. The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal. Proc Natl Acad Sci USA 95:993-998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 993-998
    • Pause, A.1    Lee, S.2    Lonergan, K.M.3    Klausner, R.D.4
  • 29
    • 0029890634 scopus 로고    scopus 로고
    • Allelic losses at chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q significantly correlate with the chromophobe subtype of renal cell carcinoma
    • Schwerdtle RF, Storkel S, Neuhaus C, Brauch H, Weidt E, Brenner W, Hohenfellner R, Huber C, Decker HJ. 1996. Allelic losses at chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q significantly correlate with the chromophobe subtype of renal cell carcinoma. Cancer Res 56:2927-2930.
    • (1996) Cancer Res , vol.56 , pp. 2927-2930
    • Schwerdtle, R.F.1    Storkel, S.2    Neuhaus, C.3    Brauch, H.4    Weidt, E.5    Brenner, W.6    Hohenfellner, R.7    Huber, C.8    Decker, H.J.9
  • 30
    • 0023651307 scopus 로고
    • RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression
    • Shapiro MB, Senapathy P. 1987. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucl Acids Res 15:7155-7175.
    • (1987) Nucl Acids Res , vol.15 , pp. 7155-7175
    • Shapiro, M.B.1    Senapathy, P.2
  • 31
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
    • Sparks AB, Morin PJ, Vogelstein B, Kinzler KW. 1998. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 58:1130-1134.
    • (1998) Cancer Res , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 33
    • 0022912449 scopus 로고
    • Histopathology and classification of renal-cell tumors (adenomas, oncocytomas and carcinomas): The basic cytological and histopathological elements and their use for diagnostics
    • Thoenes W, Storkel S, Rumpelt HJ. 1986. Histopathology and classification of renal-cell tumors (adenomas, oncocytomas and carcinomas): the basic cytological and histopathological elements and their use for diagnostics. Path Res Prac 181:125-143.
    • (1986) Path Res Prac , vol.181 , pp. 125-143
    • Thoenes, W.1    Storkel, S.2    Rumpelt, H.J.3
  • 34
    • 0029975245 scopus 로고    scopus 로고
    • Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer
    • Trybus TM, Burgess AC, Wojno KJ, Glover TW, Macoska JA. 1996. Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer. Cancer Res 56:2263-2267.
    • (1996) Cancer Res , vol.56 , pp. 2263-2267
    • Trybus, T.M.1    Burgess, A.C.2    Wojno, K.J.3    Glover, T.W.4    Macoska, J.A.5
  • 35
    • 0029941650 scopus 로고    scopus 로고
    • Identification of a novel protein (VBP1) binding to the von Hippel-Lindau tumor suppressor gene product
    • Tsuchiya H, Iseda T, Hino O. 1996. Identification of a novel protein (VBP1) binding to the von Hippel-Lindau tumor suppressor gene product. Cancer Res 56:2881-2885.
    • (1996) Cancer Res , vol.56 , pp. 2881-2885
    • Tsuchiya, H.1    Iseda, T.2    Hino, O.3
  • 37
    • 0030738693 scopus 로고    scopus 로고
    • Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
    • Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G. 1997. Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 57:2581-2585.
    • (1997) Cancer Res , vol.57 , pp. 2581-2585
    • Wolter, M.1    Reifenberger, J.2    Sommer, C.3    Ruzicka, T.4    Reifenberger, G.5


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