Vitamin B6-deficient diet plus 4-deoxypyridoxine (4-DPD) reduces the inflammatory response induced by T. spiralis in diaphragm, masseter and heart muscle tissue of mice

Molecular and Cellular Biochemistry

Volumn 197, Issue 1-2, 1999, Pages 79-85

  Frydas, S ^b   Papaioanou, N ^b   Vlemmas, I ^b   Theodoridis, I ^b   Anogiannakis, G ^b   Vacalis, D ^b   Trakatellis, A ^b   Barbacane, R C ^a   Reale, M ^a   Conti, P ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

4 deoxypyridoxine (4 DPD); Inflammation; Trichinella spiralis; Vitamin B6

Indexed keywords

DEOXYPYRIDOXINE; INTERLEUKIN 1; INTERLEUKIN 6; PYRIDOXINE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DIAPHRAGM; EOSINOPHIL; HEART MUSCLE; INFLAMMATION; INFLAMMATORY CELL; INTRAPERITONEAL DRUG ADMINISTRATION; LYMPHOCYTE; MACROPHAGE; MASSETER MUSCLE; MOUSE; NONHUMAN; TRICHINELLA SPIRALIS; VITAMIN INTAKE;

ANIMALS; DIAPHRAGM; DIET; HEART; MASSETER MUSCLE; MICE; MICE, INBRED BALB C; MYOCARDIUM; PYRIDOXINE; TRICHINELLA SPIRALIS;

ANIMALIA; TRICHINELLA SPIRALIS;

EID: 0032818707     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006958310081     Document Type: Article

References (27)

1. Ali Khan Z: The postembryonic development of Trichinella spiralis with special reference to ecdysis. J Parasitol 52: 248-257, 1966
2. Frydas S, Alexakis AE, van Knapen F: Prevalence of IgG antibodies to Trichinella spiralis in dogs in Macedonia, Northern Greece. Vet Parasitol 59: 81-89, 1994
3. Pond L, Wasson DL, Hayes CE: Evidence for differential induction of helper T cell subsets during Trichinella spiralis infection. J Immunol 143: 4232-4237, 1989
4. Cox FEG, Liew FY: T cell subsets and cytokines in parasitic infections. Immunol Today 13: 445-448, 1992
5. McDowell LR: Vitamin B6. In Vitamins in animal nutrition. Academic Press pp 236-255, 1989
6. Trakatellis AC, Axelrod AE, Montlar M, Lamy F: Induction of immune tolerance with ribosomes and ribonucleic acid extracts in newborn mice. Nature 202: 154-156, 1964
7. Axelrod AE, Trakatellis AC: Relation of pyridoxine to immunologic phenomena: Vitamins and Hormones, Academic Press New York, Vol 35, p 591, 1964
8. Trakatellis AC, Axelrod AE: Effect of pyridoxine deficiency on nucleic acid metabolism in the rat. Biochem J 95: 344-349, 1965
9. Axelrod AE, Fisher B, Lee YCP, Walsh P: Effects of pyridoxine deficiency on skin grafts in the rat. Science 127: 1388-1391, 1958
10. Trakatellis AC, Axelrod AE: Effects of pyridoxine deficiency on nucleic acid metabolism in the rat. Biochem J 95: 344-349, 1965
11. Frydas S, Trakatellis A, Karagouni E, Dotsika E, Himonas C, Conti P: 4-Deoxypiridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo. Mol Cell Biochem 136: 59-63, 1994
12. Frydas S, Karagouni E, Dotsika E, Reale M, Barbacane RC, Vlemmas I, Anogiannakis G, Trakatellis A, Conti P: Generation of TNFα, IFNγ, IL-6, IL-4 and IL-10 in mouse serum from trichinellosis: Effects of an anti-inflammatory compound 4deoxypyridoxine (4-DPD). Immunol Lett 49: 179-184, 1996
13. Haralabidis S, Frydas S, Karagouni E, Himonas C: Trichinella spiralis - Ab3 (IgG, IgM, IgA), IL-6 and TNF levels in murine Trichinellosis. Int J Immunol Pharmacol 5: 173-183, 1992
14. Frydas S, Reale M, Vacalis D, Barbacane RC, Placido F, Cataldo I, Karagouni E, Dotsika E, Trakatellis A, Conti P: IgG, IgG1 and IgM response in Trichinella spiralis infected mice treated with 4-deoxypirydoxine or fed a vitamin B6-deficient diet. Mol Cell Biochem (in press 1998)
15. Conti P, Continenza A: Decreased ulcerogenic effect of indomethacin in the rat when given in association with diflunisal. J Pathol 131: 357-363, 1980
16. Conti P, Panara MR, Frydas S, Barbacane RC, Grilli A, Placido F, Reale M, Fiore S. Inhibition of granuloma formation induced by potassium permanganate in the mouse by a specific human recombinant antagonist for interleukin-1 (hrIL-IRA). Cell Immunol 147: 446-452, 1993
17. Trakatellis A, Dimitriadou A, Exindari M, Scountzou J, Koliakos G, Christodoulou D, Malissiovas N, Antoniadis A, Polyzoni Th: Effects of pyridoxine deficiency on immunological phenomena. Postgrad Med J 68: 70-81, 1992
18. Montjar M, Axelrod AE, Trakatellis A: Effects of pyridoxine deficiency upon polysomes and messanger RNA of rat tissue. J Nutr 85: 45-65, 1965
19. Conti P, Pang X, Boucher W, Letourneau R, Reale M, Barbacane RC, Thibault J, Theoharides TC: Rantes is a proinflammatory chemokine and chemoattracts mast cells to extravascular sites. J Pathol 183: 352-358, 1997
20. Conti P, Pang X, Boucher W, Letourneau R, Reale M, Barbacane RC, Thibault J, Theoharides TC: Impact of RANTES and MCP-1 chemokines on in vivo basophilic cell recruitment in rat skin injection model and their role in modifying the protein and mRNA levels for histidine decarboxylase. Blood 89: 4120-4127, 1997
21. Conti P, Reale M, Barbacane R C, Frydas S, Felaco M, Grilli A, Placido FC, Cataldo I, Feliciani C, Di Gioacchino M, Anogianakis G, Dimitriadou D, Vacalis D, Trakatellis A: Massive infiltration of basophilic cells in inflamed tissue after injection of RANTES. Immunol Lett 58: 101-106, 1997
22. Conti P, Boucher W, Letourneau R, Feliciani C, Reale M, Barbacane RC, Vlagopoulos P, Bruneau G, Thibault J, Theoharides TC: Monocyte chemotactic protein 1 (MCP-1) is a potent histamine and [3H]-5HT-releasing factor for mast cells and provokes cell aggregation. Immunology 86: 434-440, 1995
23. Schall TT, Bacon K, Karen JT, Goeddel DV: Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347: 669-673, 1990
24. Conti P, Reale M, Feliciani C, Frydas S, Trakatellis M, Placido F, Cataldo I, Di Gioacchino M, Barbacane R.C: Augmentation of monocyte chemotactic protein-1 and mRNA transcript in chronic inflammatory states induced by potassium permanganate (KMnO4) in vivo. Immunology 92: 300-306, 1997
25. Haralabidis S, Daoudaki M, Frydas S: T cell populations and IL-6, IL-10, TNF-alpha and specific immunoglobulin levels in murine trichinellosis. Int J Immunopathol Pharmacol 6: 149-157, 1993
26. Karagouni E, Frydas S, Dotsika E, Himonas C, Conti P, Trakatellis A: Inhibition of TNF-α and IL-6, but not IFN-γ, by 4-deoxypyridoxine (4-DPD) in Trichinella-infected mouse serum. Int J Immunopathol Pharmacol 8: 9-14, 1995
27. Trakatellis A, Exindari M, Haitoglou CS, Christodoulou D, Dimitriadou A: Serum hydroxymethyltransferase (SHMT) as a precise indicator of antiproliferative or immunosuppressive potency of various compounds. Int J Immunopathol Pharmacol 8: 31-37, 1995