Inhibitory effects of estradiol on inward rectifier and delayed rectifier K+ currents in guinea pig ventricular myocytes

Acta Pharmacologica Sinica

Volumn 20, Issue 7, 1999, Pages 631-634

  Zhang, Yi ^a   Song, Li Lin ^b   Gu, Shuang Zhen ^b   Lu, Shen Gui ^b   Zhou, Zhao Nian ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Action potentials; Estradiol; Myocardium; Patch clamp techniques; Potassium channels

Indexed keywords

ESTRADIOL; POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GUINEA PIG; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART VENTRICLE WALL; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT;

ACTION POTENTIALS; ANIMALS; CELL SEPARATION; ESTRADIOL; GUINEA PIGS; MALE; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS;

EID: 0032817434     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Morise AP, Dalal JN, Duval RD. Value of simple measure of estrogen Status for improving the diagnosis of coronary artery disease in women. Am J Med 1993; 94: 491-6.
2. Collins P, Rosano CMC, Jiang C, Lindsay D, Sarrel PM, Poole-Wilson PA. Cardiovascular protection by oestrogen; a calcium antagonist effects? Lancet 1993; 341: 1264-5.
3. Barta E, Strec V, Styk J, Okolicany J, Rajecova O. Protective effect of oestradiol on the heart of rats exposed to acute ischaemia. Physiol Bohemoslov 1989; 38: 193-200.
4. Myrup B, Jensen GF, McNair P. Cardiovascular risk factors during estrogen-norethindrone and cholecalciferol treatment. Arch Intern Med 1992; 152: 2265-8.
5. Raddino R, Poli E, Pela G, Manca C. Action of steroid sex hormones on the isolated rabbit heart. Pharmacology 1989; 38: 185-90.
6. Zheng ZZ. The effects of sex hormone on cardiovascular system. Basic Med Sci Clin 1987; 7: 16-21.
7. Zhang Y, Hao YC, Song LL, Guo SM, Gu SZ, Lu SG. Effects of sex hormones on action potential and contraction of guinea pig papillary muscle. Acta Pharmacol Sin 1998; 19; 248-50.
8. Farmer BB, Mancina M, Williams ES, Watanabe AM. Isolation of calcium tolerance myocytes from adult rat hearts: review of the literature and description of a method. Life Sci 1983; 33: 1-18.
9. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 1981; 391: 85-100.
10. Zheng ZZ, He LP, Li CQ, Shao ZH, Li YJ, Song SJ, et al. Protection of anerobic heart in vitro by estradiol in its physiological level. Chin J Cardiol 1989; 17: 45-47.
11. Stumpf WE, Sar M, Aumüller G. The heart: a target organ for estradiol. Science 1977; 196: 319-21.
12. Fermini B, Jurkiewicz NK, Jow B, Guinosso PJ Jr, Baskin EP, Lynch JJ Jr, et al. Use-dependent effects of the class III antiarrhythmic agent NE-10064 (Azimilide) on cardiac repolarization: block of delayed rectifier potassium and L-type calcium currents. J Cardiovasc Pharmacol 1995; 26: 259-71.
13. 2+ in guinea-pig isolated cardiac myocytes. Br J Pharmacol 1992; 106: 739-45.
14. Wang XQ, Jiang Y, Zhong GG, Yang GY. Influence of estradiol benzoate on the electric activity of primary cultured rat heart cells. Chin J Endemiol 1990; 9: 347-49.