TMC-169, a new antibiotic of the aspochalasin group produced by Aspergillus flavipes

Journal of Antibiotics

Volumn 52, Issue 6, 1999, Pages 575-577

  Kohno, Jun ^a   Nonaka, Nobuaki ^a   Nishio, Maki ^a   Ohnuki, Tetsuo ^a   Kawano, Kimio ^a   Okuda, Toru ^a   Komatsubara, Saburo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ASPOCHALASIN DERIVATIVE; TMC 169; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; ASPERGILLUS; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ASPERGILLUS FLAVIPES;

EID: 0032816829     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.575     Document Type: Article

References (5)

1. KELLER-SCHIERLEIN, W. & E. KUPFER: Metabolites of microorganisms. 186. The aspochalasins A, B, C and D. Helv. Chim. Acta 62: 1501-1524, 1979
2. NARUSE, N.; H. YAMAMOTO, S. MURATA, Y. SAWADA, Y. FUKAGAWA & T. OKI: Aspochalasin E, a new antibiotic isolated from a fungus. J. Antibiotics 46: 679-681, 1993
3. FANG, F.; H. UI, K. SHIOMI, R. MASUMA, Y. YAMAGUCHI, C. G. ZHANG, X. W. ZHANG, Y. TANAKA & S. ŌMURA: Two new components of the aspochalasins produced by Aspergillus sp. J. Antibiotics 50: 919-925, 1997
4. ALVI, K. A.; B. NAIR, H. PU, R. URSINO, C. GALLO & U. MOCEK: Phomacins: Three novel antitumor cytochalasan constituents produced by a phoma sp. J. Org. Chem. 62: 2148-2151, 1997
5. KOHNO, J.; M. NISHIO, K. KAWANO, N. NAKANISHI, S. SUZUKI, T. UCHIDA & S. KOMATSUBARA: TMC-1 A, B, C and D, new antibiotics of the manumycin group produced by Streptomyces sp. Taxonomy, production, isolation, physico-chemical properties, structure elucidation and biological properties, J. Antibiotics 49: 1212-1220, 1996