Synthesis and preliminary evaluation of [18F]2-deoxy-2,2-difluoro-glucose as a potential PET imaging agent

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 42, Issue 8, 1999, Pages 809-813

  Adam, Michael J ^a  

^a TRIUMF   (Canada)

Author keywords

Acetyl hypofluorite; Fluoro deoxy glucose; Glucose metabolism; Positron emission tomography

Indexed keywords

BRAIN MAPPING; GLUCOSE;

2-DEOXY-2; ACETYL HYPOFLUORITE; DEPROTECTION; FLUORO-DEOXY-GLUCOSE; GLUCOSE METABOLISM; IMAGING AGENT; IN-VIVO; PET IMAGING; POTENTIAL IMAGING; VIVO STUDIES;

POSITRON EMISSION TOMOGRAPHY;

FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; HEART; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RHESUS MONKEY;

ANIMALIA; MACACA MULATTA;

EID: 0032816360     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199908)42:8<809::AID-JLCR241>3.0.CO;2-8     Document Type: Article

References (5)

1. McCarter J.D., Adam M.J., and Withers S.G. -Carbohydrate Res., 266: 273-277 (1995).
2. Adamson J., Foster A.B., Westwood J.H. -Carbohydrate Res., 18: 345-347 (1971).
3. Jewett D.M., Potocki J.F., Ehrenkaufer R.E. -J. Fluorine Chem. 24: 477-484 (1984).
4. Adamson J., Foster A.B., Hall L.D., Johnson R.N., and Hesse R.H. -Carbohydrate Res. 15: 351-359 (1970).
5. Gallagher B.M., Ansari A., Atkins H., Casella V., Christman D.R., Fowler J.S., Ido T., MacGregor R.R., Som P., Wan C.N., Wolf A.P., Kuhl D.E., and Reivich M. -J. Nucl. Med. 18: 990-996 (1977).