The 9-kDa N-terminal propeptide domain of MT1-MMP is required for the activation of progelatinase A

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 710-712

  Cao, Jian ^a   Drews, Michelle ^b   Lee, Hsi M ^a   Conner, Cathleen ^b   Bahou, Wadie F ^a   Zucker, Stanley ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE;

AMINO TERMINAL SEQUENCE; CONFERENCE PAPER; ENZYME ACTIVATION; STRUCTURE ACTIVITY RELATION;

EID: 0032816042     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07769.x     Document Type: Conference Paper

References (3)

1. 1. Sato, H., T. Takino, Y. Okada et al. 1994. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370: 61-65.
2. 2. Cao, J., A. Rehemtulla, W. Bahou et al. 1996. Membrane type matrix metalloproteinase I activates pro-gelatinase A without furin cleavage of the N-terminal domain. J. Biol. Chem. 271: 30174-30180.
3. 3. Zucker, S., M. Drews, C. Conner et al. 1998. Tissue inhibitor of metalloproteinase-2 binds to the catalytic domain of the cell surface receptor, membrane type 1 metalloproteinase I. J. Biol. Chem. 273: 1216-1222.