Successful treatment of right heart thromboemboli with IV recombinant tissue-type plasminogen activator during continuous echocardiographic monitoring. A case series report

Chest

Volumn 116, Issue 1, 1999, Pages 78-82

  Greco, Francesco ^a,c   Bisignani, Giovanni ^a   Serafini, Oscar ^a   Guzzo, Domenico ^a   Stingone, Angela ^b   Plastina, Franco ^a  

^a Osp Civ Annunziata   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c NONE   (Italy)

Author keywords

Echocardiography; Pulmonary embolism; Recombinant tissue type plasminogen activator; Thrombus

Indexed keywords

ALTEPLASE;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; COR PULMONALE; DRUG EFFECT; FEMALE; FIBRINOLYTIC THERAPY; HEART RIGHT VENTRICLE; HUMAN; LUNG PERFUSION; MALE; MONITORING; PRIORITY JOURNAL; PROGNOSIS; THROMBOEMBOLISM; TRANSTHORACIC ECHOCARDIOGRAPHY;

EID: 0032814782     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.116.1.78     Document Type: Article

References (23)

1. 1 Kasper W, Meinertz T, Henkel B, et al. Echocardiographic findings in patients with proved pulmonary embolism. Am Heart J 1986; 112:1284-1290
2. 2 Chapoutot L, Nazeyrollas P, Metz D, et al. Floating right heart thrombi and pulmonary embolism: diagnosis, outcome and therapeutic management. Cardiology 1996; 87:169-174
3. 3 Casazza F, Bongarzone A, Centonze F, et al. Prevalence and prognostic significance of right-sided cardiac mobile thrombi in acute pulmonary embolism. Am J Cardiol 1997; 79:44-46
4. 4 Franzoni P, Cuccia C, Zappa G, et al. Tromboembolo migrante nelle cavità cardiache destre in corso di embolia polmonare. G Ital Cardiol 1989; 19:7-16
5. 5 Kronik G, The European Working Group on Echocardiography. The European Cooperative Study on the clinical significance of right heart thrombi. Eur Heart J 1989; 10:1046-1059
6. 6 Torbicki A, the RAMT Outcome Registry Contributors. Therapeutic preference and outcome of various treatment of venous clots trapped in the right atrium: preliminary results of a European registry [abstract]. Eur Heart J 1996; 17(suppl):244
7. 7 Farfel Z, Shechter M, Vered Z, et al. Review of echocardiographically diagnosed right heart entrapment of pulmonary emboli-in-transit with emphasis on management. Am Heart J 1987; 133:171-178
8. 8 Covarrubias EA, Sheikh MU, Fox LM, et al. Echocardiography and pulmonary embolism. Ann Intern Med 1977; 87:720
9. 9 Kinney EL, Wright RG. Efficacy of treatment of patients with echocardiographically detected right-sided heart thrombi: a meta-analysis. Am Heart J 1989; 118:569-573
10. 10 Tavel ME, Goldhaber SZ, Moser KM. Rapidly progressing dyspnea associated with a mass in the right side of the heart. Chest 1995; 107:866-868
11. 11 Starkey IR, De Bono DP. Echocardiographic identification of right-sided cardiac intracavitary thromboembolus in massive pulmonary embolism. Circulation 1982; 66:1322-1325
12. 12 Ouyang P, Camara EJ, Jain A, et al. Intracavitary thrombi in the right heart associated with multiple pulmonary emboli: report of two patients. Chest 1983; 84:296-299
13. 13 Armstrong WF, Feigenbaum H, Dillon JC. Echocardiographic detection of right-atrial thromboembolism. Chest 1985; 87:801-805
14. 14 Mancuso L, Marchi S, Mizio G, et al. Echocardiographic detection of right-sided cardiac thrombi in pulmonary embolism. Chest 1987; 92:23-26
15. 15 Goldhaber SZ, Nagel JS, Theard M, et al. Treatment of right atrial thrombus with urokinase. Am Heart J 1988; 115:894-897
16. 16 Minutiello L. Dissoluzione dopo trattamento con rt-PA di tromboembolo migrante in cavità cardiache destre in corso di embolia polmonare. Descrizione di un caso trattato con successo. Minerva Cardioangiol 1993; 41:49-56
17. 17 Mafrici A, Alberti A, Corrado E, et al. Risoluzione della trombosi atriale destra di recente insorgenza durante infusione endovenosa di rt-PA: descrizione di tre casi con monitoraggio ecocardiografico continuo. G Ital Cardiol 1993; 23:479-484
18. 18 Stefanini MG, Mobilia G, Buchberger R. Tromboembolo flottante neue cavità cardiache destre in corso di embolia polmonare. Minerva Cardioangiol 1997; 45:21-24
19. 19 Cuccia C, Campana M, Franzoni P, et al. Effectiveness of intravenous rt-PA in the treatment of massive pulmonary embolism and right heart thromboembolism. Am Heart J 1993; 126:468-472
20. 20 Chapoutot L, Metz D, Canivet E, et al. Thrombus mobile du coeur droit et embolie pulmonaire: problemes diagnostique et therapeutique a propos de 12 cas. Arch Mal Coeur Vaiss 1993; 86:1039-1045
21. 21 Goldhaber SZ, Vaughan DE, Markis JE, et al. Acute pulmonary embolism treated with tissue plasminogen activator. Lancet 1986; 2:886-889
22. 22 Goldhaber SZ, Haire WD, Feldstein ML, et al. Alteplase versus heparin in acute pulmonary embolism: randomized trial assessing right-ventricular function and pulmonary perfusion. Lancet 1993; 341:507-511
23. 23 Metz D, Nazeyrollas P, Mailler B, et al. Regression of right ventricular hypokinesis after thrombolysis in acute pulmonary embolism. Am J Cardiol 1996; 77:1252-1254