Nitric oxide synthase-containing projections to the ventrobasal thalamus in the rat

Anatomy and Embryology

Volumn 200, Issue 3, 1999, Pages 265-281

  Usunoff, Kamen G ^a   Kharazia, Viktor N ^b   Valtschanoff, Juli G ^b   Schmidt, Harald H H W ^c   Weinberg, Richard J ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cholinergic; Laterodorsal tegmental nucleus; Pedunculopontine nucleus; Retrograde axonal transport; Somatosensory system

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; IONTOPHORESIS; LATERAL HYPOTHALAMUS; MALE; NERVE CELL; NERVE FIBER; NEUROTRANSMISSION; NONHUMAN; PONS; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; RETICULAR FORMATION; RETROGRADE NERVE FIBER TRANSPORT; SOMATOSENSORY SYSTEM; SPINAL CORD; TEGMENTUM; THALAMUS; TRIGEMINAL NUCLEUS;

AFFERENT PATHWAYS; ANIMALS; EVOKED POTENTIALS, SOMATOSENSORY; IMMUNOHISTOCHEMISTRY; NEURONS; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTIC TRANSMISSION; THALAMUS;

ANIMALIA;

EID: 0032814467     PISSN: 03402061     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004290050278     Document Type: Article

References (118)

1. Barbaresi P, Spreafico R, Frassoni C, Rustioni R (1986) GABAergic neurons are present in the dorsal column nuclei but not in the ventroposterior complex of rats. Brain Res 382:305-326
2. Beninato M, Spencer RF (1988) The cholinergic innervation of the rat substantia nigra: a light and electron microscopic immunohistochemical study. Exp Brain Res 72:178-184
3. Bertini G, Bentivoglio M (1997) Nitric oxide synthase in the adult and developing thalamus: histochemical and immunohistochemical study in the rat. J Comp Neurol 388:89-105
4. Bertini G, Peng Z-C, Bentivoglio M (1996) The chemical heterogeneity of cortical interneurons: Nitric oxide synthase vs. calbindin and parvalbumin immunoreactivity in the rat. Brain Res Bull 39:261-266
5. Bevan MD, Bolam JP (1995) Cholinergic, GABAergic, and glutamate-enriched inputs from the mesopontine tegmentum to the subthalamic nucleus in the rat. J Neurosci 15:7105-7120
6. Bickford ME, Günlük AE, Guido W, Sherman SM (1993) Evidence that cholinergic axons from the parabrachial region of the brainstem are the exclusive source of nitric oxide in the lateral geniculate nucleus of the cat. J Comp Neurol 334:410-430
7. Bidmon HJ, Wu J, Gödecke A, Schleicher A, Mayer B, Zilles K (1997) Nitric oxide synthase-expressing neurons are area-specifically distributed within the cerebral cortex of the rat. Neuroscience 81:321-330
8. Blottner D, Grozdanovic Z, Gossrau R (1995) Histochemistry of nitric oxide synthase in the nervous system. Histochem J 27:785-811
9. Bolam JP, Francis CM, Henderson Z (1991) Cholinergic input to dopaminergic neurons in the substantia nigra: a double immunocytochemical study. Neuroscience 41:483-494
10. Bredt DS, Snyder SH (1992) Nitric oxide: a novel neuronal messenger. Neuron 8:3-11
11. Burstein R, Dado RJ, Giesler GJ Jr (1990) The cells of origin of the spinothalamic tract of the rat: a quantitative reexamination. Brain Res 511:329-337
12. Castaldi L (1926) Studi sulla struttura e sullo sviluppo del mesencefalo: Ricerche in Cavia Cobaya. Parte 3. Arch Ital Anat Embriol 23:481-609
13. Clarke NP, Bevan MD, Cozzari C, Hartman BK, Bolam JP (1997) Glutamate-enriched cholinergic synaptic terminals in the entopeduncular nucleus and subthalamic nucleus of the rat. Neuroscience 81:371-385
14. Cornwall J, Cooper JD, Phillipson OT (1990) Afferent and efferent connections of the laterodorsal tegmental nucleus in the rat. Brain Res Bull 25:271-284
15. Cropper EC, Eisenman JS, Azmitia EC (1984) An immunocytochemical study of the serotonergic innervation of the thalamus of the rat. J Comp Neurol 224:38-50
16. Cudeiro J, Rivadulla C, Rodriguez R, Martinez-Conde S, Martinez L, Grieve KL, Acuna C (1996) Further observations on the role of nitric oxide in the feline lateral geniculate nucleus. Eur J Neurosci 8:144-152
17. Dawson TN, Snyder SH (1994) Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J Neurosci 14:5147-5159
18. Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH (1991) Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci USA 88:7797-7801
19. Do K-Q, Binns KE, Salt TE (1994) Release of the nitric oxide precursor, arginine, from the thalamus upon sensory afferent stimulation, and its effect on thalamic neurons in vivo. Neuroscience 60:581-586
20. Dohrn CS, Mullett MA, Price RH, Beitz AJ (1994) Distribution of nitric oxide synthase-immunoreactive interneurons in the spinal trigeminal nucleus. J Comp Neurol 346:449-460
21. Dun NJ, Dun SL, Forstermann U (1994) Nitric oxide synthase immunoreactivity in rat pontine medullary neurons. Neuroscience 59:429-445
22. El Mansari M, Sakai K, Jouvet M (1989) Unitary characteristics of presumptive cholinergic tegmental neurons during the sleepwalking cycle in freely moving cats. Exp Brain Res 76:509-529
23. Ferssiwi A, Cardo B, Velley L (1987) Electrical self-stimulation in the parabrachial area is depressed after ibotenic acid lesion of the lateral hypothalamus. Behav Brain Res 25:109-116
24. Fulwiler CE, Saper CB (1984) Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Res Rev 7:229-259
25. Gabbott PL, Bacon SJ (1994) Two types of interneuron in the dorsal lateral geniculate nucleus of the rat: a combined NADPH diaphorase histochemical and GABA immunocytochemical study. J Comp Neurol 350:281-301
26. Garcia-Rill E (1991) The pedunculopontine nucleus. Prog Neurobiol 36:363-389
27. Garcia-Rill E, Biedermann JA, Chambers T, Skinner RD, Mrak RE, Husain M, Karson CN (1995) Mesopontine neurons in schizophrenia. Neuroscience 66:321-335
28. Garthwaite J, Boulton CL (1995) Nitric oxide signaling in the central nervous system. Annu Rev Physiol 57:683-706
29. Geula C, Schatz CR, Mesulam M-M (1993) Differential localization of NADPH-diaphorase and Calbindin-D28k within the cholinergic neurons of the basal forebrain, striatum and brainstem in the rat, monkey, baboon and human. Neuroscience 54:461-476
30. Gonchar YA, Johnson PB, Weinberg RJ (1995) GABA-immunopositive neurons in rat neocortex with contralateral projections to S-I. Brain Res 697:27-34
31. Gould E, Butcher LL (1986) Cholinergic neurons in the rat substantia nigra. Neurosci Lett 63:315-319
32. Granum SL (1986) The spinothalamic system of the rat. I. Locations of cells of origin. J Comp Neurol 247:159-180
33. Grofova I, Keane S (1991) Descending brain stem projections of the pedunculopontine tegmental nucleus in the rat. Anat Embryol 183:275-290
34. Hallanger AE, Wainer BH (1988) Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat. J Comp Neurol 274:483-515
35. Hallanger AE, Levey AI, Lee HJ, Rye DB, Wainer BH (1987) The origins of cholinergic and other subcortical afferents to the thalamus in the rat. J Comp Neurol 262:105-124
36. Halliday G, Harding A, Paxinos G (1995) Serotonin and tachykinin systems. In: Paxinos G (ed) the rat nervous system, 2nd edn. Academic Press, San Diego, pp 929-974
37. Harris RM, Hendrickson AE (1987) Local circuit neurons in the rat ventrobasal thalamus - a GABA immunocytochemical study. Neuroscience 21:229-236
38. Henderson Z (1987) Overlap in the distribution of cholinergic and catecholaminergic neurons in the ferret. J Comp Neurol 265:581-592
39. Herkenham M (1979) The afferent and efferent connections of the ventromedial thalamic nucleus in the rat. J Comp Neurol 183:487-518
40. Hope BT, Michael GJ, Knigge KM, Vincent SR (1991) Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA 88:2811-2814
41. Inglis WL, Semba K (1996) Co-localization of iontotropic glutamate receptor subunits with NADPH-diaphorase-containing neurons in the rat mesopontine tegmentum. J Comp Neurol 368:17-32
42. Inglis WL, Winn P (1995) The pedunculopontine tegmental nucleus: where the striatum meets the reticular formation. Proc Neurobiol 47:1-29
43. Jacobsohn L (1909) Über die Kerne des menschlichen Himstammes. Abhandlungen der Königlichen Preussischen Akad Wiss 1:1-70
44. Johnson MD, Ma PM (1993) Localization of NADPH diaphorase activity in monoaminergic neurons of the rat brain. J Comp Neurol 332:391-406
45. Jones BE (1990) Immunohistochemical study of choline acetyltransferase-immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat. J Comp Neurol 295:485-514
46. Jones BE (1991) Paradoxical sleep and its chemical and structural substrates in the brain. Neuroscience 40:637-656
47. Jones BE (1995) Reticular formation: cytoarchitecture, transmitters, and projections. In: Paxinos G (ed) The rat nervous system, 2nd edn. Academic Press, San Diego, pp 155-171
48. Jones BE, Beaudet A (1987) Distribution of acetylcholine and catecholamine neurons in the cat brainstem: a choline acetyltransferase and tyrosine hydroxylase immunohistochemical study. J Comp Neurol 261:15-32
49. Jones EG (1985) The thalamus. Plenum Press, New York
50. Karson CN, Garcia-Rill E, Biedermann J, Mrak RE, Husain MM, Skinner RD (1991) The brain stem reticular formation in schizophrenia. Psychiatry Res 40:31-48
51. Kemplay SK, Webster KE (1986) A qualitative and quantitative analysis of the distributions of cells in the spinal cord and spinomedullary junction projecting to the thalamus of the rat. Neuroscience 17:769-789
52. Kharazia VN, Petrusz P, Usunoff K, Weinberg RJ, Rustioni A (1997) Arginine and NADPH diaphorase in the rat ventroposterior thalamic nucleus. Brain Res 744:151-155
53. Lee HJ, Rye DB, Hallanger HE, Levey AI, Wainer BH (1988) Cholinergic vs. non-cholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei. J Comp Neurol 275:469-492
54. Lee J-H, Price RH, Williams FG, Mayer B, Beitz AJ (1993) Nitric oxide synthase is found in some spinothalamic neurons and in neuronal processes that appose spinal neurons that express Fos induced by noxious stimulation. Brain Res 608:324-333
55. Leonard CS, Kerman I, Blaha G, Taveras E, Taylor B (1995) Interdigitation of nitric oxide synthase-, tyrosine hydroxylase-, and serotonin-containing neurons in and around the laterodorsal and pedunculopontine tegmental nuclei of the guinea pig. J Comp Neurol 362:411-432
56. Levey AI, Hallanger AE, Wainer BH (1987) Cholinergic nucleus basalis neurons may influence the cortex via the thalamlus. Neurosci Lett 74:7-13
57. Llewellyn-Smith IJ, Minson JB (1992) Complete penetration of antibodies into vibratome sections after glutaraldehyde fixation and ethanol treatment: light and electron microscopy for neuropeptides. J Histochem Cytochem 40:1741-1749
58. Losier BJ, Semba K (1993) Dual projections of single cholinergic and aminergic brainstem neurons to the thalamus and basal forebrain in the rat. Brain Res 604:41-52
59. Meng XW, Ohara PT, Ralston HJ 3rd (1996) Nitric oxide synthase immunoreactivity distinguishes a sub-population of GABA-immunoreactive neurons in the ventrobasal complex of the cat. Brain Res 728:111-115
60. Mesulam M-M, Mufson EJ, Wainer BH, Levey AI (1983) Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 10:1185-1201
61. Mitrofanis J (1992) NADPH diaphorase reactivity in the ventral and dorsal lateral geniculate nuclei of rats. Vis Neurosci 9:211-216
62. Miyazaki M, Kayama Y, Kihara T, Kawasaki K, Yamaguchi E, Wada Y, Ikeda M (1996) Possible release of nitric oxide from cholinergic axons in the thalamus by stimulation of the rat laterodorsal tegmental nucleus as measured with voltammetry. J Chem Neuroanat 10:203-207
63. Mizukawa K, Vincent SR, McGeer PL, McGeer EG (1989) Distribution of reduced-nicotinamide-adenine-dinucleotide-phosphate-diaphorase-positive cells and fibers in the cat central nervous system. J Comp Neurol 279:281-311
64. Nakamura H, Saheki T, Ichiki H, Nakata K, Nakagawa S (1991) Immunocytochemical localization of argininosuccinate synthetase in the rat brain. J Comp Neurol 312:652-679
65. Newman DB, Ginsberg CY (1994) Brainstem reticular nuclei that project to the thalamus in rats: a retrograde tracer study. Brain Behav Evol 44:1-39
66. Nothias F, Onteniente B, Roudier F, Peschanski M (1988) Immunocytochemical study of serotoninergic and noradrenergic innervation of the ventrobasal complex of the rat thalamus. Neurosci Lett 95:59-63
67. Oh JD, Woolf NJ, Roghani A, Edwards RH, Butcher LL (1992) Cholinergic neurons in the rat central nervous system demonstrated by in situ hybridization of choline acetyltransferase mRNA. Neuroscience 47:807-822
68. Olszewski J, Baxter D (1954) Cytoarchitecture of the human brain stem. Lippincott, Philadelphia
69. Onstott D, Mayer B, Beitz AJ (1993) Nitric oxide synthase immunoreactive neurons anatomically define a longitudinal dorsolateral column within the midbrain periaqueductal gray of the rat: analysis using laser confocal microscopy. Brain Res 610:317-324
70. Otake K, Ruggiero DA (1995) Monoamines and nitric oxide are employed by afferents engaged in midline thalamic regulation. J Neurosci 15:1891-1911
71. Pape H-C, Mager R (1992) Nitric oxide controls oscillatory activity in thalamocortical neurons. Neuron 9:441-448
72. Parent A, Pare D, Smith Y, Steriade M (1988) Basal forebrain cholinergic and noncholinergic projections to the thalamus and brainstem in cats and monkeys. J Comp Neurol 277:281-301
73. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, Sydney, Australia
74. Peschanski M, Besson J-M (1984) Diencephalic connections of the raphe nuclei of the rat brainstem: an anatomical study with reference to the somatosensory system. J Comp Neurol 224:509-534
75. Price JL (1995) Thalamus. In: Paxinos G (ed) The rat nervous system, 2nd edn. Academic Press, San Diego, pp 629-648
76. Rodrigo J, Springall DR, Uttenthal O, Bentura ML, Abadia-Molina F, Riveros-Moreno V, Martinez-Murillo R, Polak JM, Moncada S (1994) Localization of nitric oxide synthase in the adult rat brain. Phil Trans R Soc Lond B Biol Sci 345:175-221
77. Rye DB, Saper CB, Lee HJ, Wainer BH (1987) Pedunculopontine tegmental nucleus of the rat. Cytoarchitecture, cytochemistry and some extrapyramidal connections of the mesopontine tegmentum. J Comp Neurol 259:483-528
78. Saper CB (1984) Organization of cerebral cortical afferent systems in the rat. I. Magnocellular basal nucleus. J Comp Neurol 222:313-342
79. Saper CB, Loewy AD (1982) Projections of the pedunculopontine tegmental nucleus in the rat: evidence for additional extrapyramidal circuitry. Brain Res 252:367-372
80. Satoh K, Arai R, Ikemoto K, Narita M, Nagai T, Ohshima H, Kitahama K (1995) Distribution of nitric oxide synthase in the central nervous system of Macaca fuscata: subcortical regions. Neuroscience 66:685-696
81. Schmidt HHHW, Gagne GD, Nakane M, Pollock JS, Miller MF, Murad F (1992) Mapping of neuronal nitric oxide synthase in the rat suggests frequent colocalization with NADPH diaphorase but not soluble guanylyl cyclase and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem 40:1439-1456
82. Shaw PJ, Salt TE (1997) Modulation of sensory and excitatory amino acid responses by nitric oxide donors and glutathione in the ventrobasal thalamus of the rat. Eur J Neurosci 9:1507-1513
83. Sofroniew MV, Priestley JV, Consolazione A, Eckenstein F, Cuello AC (1985) Cholinergic projections from the midbrain and pons to the thalamus in the rat, identified by combined retrograde tracing and choline acetyltransferase immunohistochemistry. Brain Res 329:213-223
84. Spann BM, Grofova I (1992) Cholinergic and non-cholinergic neurons in the rat pedunculopontine tegmental nucleus. Anat Embryol 186:215-227
85. Spreafico R, Schmechel DE, Ellis LC Jr, Rustioni A (1983) Cortical relay neurons and interneurons in the n. ventralis posterolateralis of cats: a horseradish peroxidase, electronmicroscopic, Golgi and immunocytochemical study. Neuroscience 9:491-510
86. Spreafico R, Amadeo A, Angoscini P, Panzica F, Battaglia G (1993) Branching projections from mesopontine nuclei to the nucleus reticularis and related thalamic nuclei: a double labelling study in the rat. J Comp Neurol 336:481-492
87. Stanley BG, Willett III VL, Donias HW, Dee II MG, Duva MA (1996) Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control. Am J Physiol 270:R443-R449
88. Steckler T, Inglis W, Winn P, Sahgal A (1994) The pedunculopontine tegmental nucleus: a role in cognitive processes? Brain Res Rev 19:298-318
89. Steinbusch HWM (1981) Distribution of serotonin-immunoreactivity in the central nervous system of the rat - cell bodies and terminals. Neuroscience 6:557-618
90. Steriade M, McCarley R (1990) Brainstem control of wakefulness and sleep. Plenum Press, New York
91. Sugaya K, McKinney M (1994) Nitric oxide synthase gene expression in cholinergic neurons in the rat brain examined by combined immunocytochemistry and in situ hybridization histochemistry. Mol Brain Res 23:111-125
92. Swanson LW (1992) Brain maps: structure of the rat brain. Elsevier, Amsterdam
93. Takakusaki K, Shiroyama T, Yamamoto T, Kitai ST (1996) Cholinergic and noncholinergic tegmental pedunculopontine projection neurons in rats revealed by intracellular labeling. J Comp Neurol 371:345-361
94. Takemura M, Wakisaka S, Yoshida A, Nagase Y, Bae YC, Shigenaga Y (1994) NADPH-diaphorase in the spinal trigeminal nucleus oralis and rostral solitary tract nucleus of rats. Neuroscience 61:587-595
95. Thomas E, Pearse AGE (1964) The solitary active cells: histochemical demonstration of damage-resistant nerve cells with a TPN-diaphorase reaction. Acta Neuropathol (Berl) 3:238-249
96. Valtschanoff JG, Weinberg RJ, Rustioni A (1992) NADPH diaphorase in the spinal cord of rats. J Comp Neurol 321:209-222
97. Valtschanoff JG, Weinberg RJ, Kharazia VN, Schmidt HHHW, Nakane M, Rustioni A (1993) Neurons in rat cerebral cortex that synthesize nitric oxide: NADPH diaphorase histochemistry, NOS immunocytochemistry, and colocalization with GABA. Neurosci Lett 157:157-161
98. Vertes RP (1991) A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat. J Comp Neurol 313:643-668
99. Vertes RP, Martin GF (1988) Autoradiographic analysis of ascending projections from the pontine and mesencephalic reticular formation and the median raphe nucleus in the rat. J Comp Neurol 275:511-541
100. Vertes RP, Martin GF, Waltzer R (1986) An autoradiographic analysis of ascending projections from the medullary reticular formation in the rat. Neuroscience 19:873-898
101. Vincent SR (1986) NADPH-diaphorase histochemistry and neurotransmitter coexistence. In: Panula P, Paivarinta H, Soinila S (eds) Neurohistochemistry: modern methods and applications. Liss, New York, pp 375-396
102. Vincent SR (1994) Nitric oxide: a radical neurotransmitter in the central nervous system. Prog Neurobiol 42:129-160
103. Vincent SR, Hope BT (1992) Neurons that say NO. Trends Neurosci 15:108-113
104. Vincent SR, Kimura H (1992) Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46:755-784
105. Vincent SR, Satoh K, Armstrong DM, Fibiger HC (1983) NADPH-diaphorase: a selective histochemical marker for the cholinergic neurons of the pontine reticular formation. Neurosci Lett 43:31-36
106. Vincent SR, Satoh K, Armstrong DM, Panula P, Vale W, Fibiger HC (1986) Neuropeptides and NADPH-diaphorase activity in the ascending cholinergic reticular system of the rat. Neuroscience 17:167-182
107. Wainer B, Mesulam M-M (1990) Ascending cholinergic pathways in the rat brain. In: Steriade M, Biesold D (eds) Brain cholinergic systems. Oxford University Press, New York, pp 65-119
108. Waite PME, Tracey DJ (1995) Trigeminal sensory system. In: Paxinos G (ed) The rat nervous system, 2nd edn. Academic Press, San Diego, pp 705-724
109. Wang QP, Guan JL, Nakai Y (1995) Distribution and synaptic relations of NOS neurons in the dorsal raphe nucleus: a comparison to 5-HT neurons. Brain Res Bull 37:177-187
110. Weinberg RJ, Valtschanoff JG, Schmidt HHHW (1996) The NADPH-diaphorase histochemical stain. In: Feelisch M, Stamler JS (eds) Methods in nitric oxide research. Wiley, London, pp 237-248
111. Williams JA, Vincent SR, Reiner PB (1997) Nitric oxide production in rat thalamus changes with behavioral state, local depolarization, and brainstem stimulation. J Neurosci 17:420-427
112. Woolf NJ (1991) Cholinergic systems in mammalian brain and spinal cord. Prog Neurobiol 37:475-524
113. Woolf NJ, Butcher LL (1986) Cholinergic systems in the rat brain. III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain. Brain Res Bull 16:603-637
114. Wotherspoon G, Albert M, Rattray M, Priestley JV (1994) Serotonin and NADPH-diaphorase in the dorsal raphe nucleus of the adult rat. Neurosci Lett 173:31-36
115. Yamada K, Emson P, Hökfelt T (1996) Immunohistochemical mapping of nitric oxide synthase in the rat hypothalamus and colocalization with neuropeptides. J Chem Neuroanat 10:295-316
116. Yan XX, Jen LS, Garey LJ (1996) NADPH-diaphorase-positive neurons in primate cerebral cortex colocalize with GABA and calcium-binding proteins. Cereb Cortex 6:524-529
117. Yeomans J (1995) Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia. Neuropsychopharmacology 12:3-16
118. Yeomans J, Kofman O, McFarlane V (1985) Cholinergic involvement in lateral hypothalamic rewarding brain stimulation. Brain Res 329:19-26