Competitive polymerase chain reaction for the determination of N-myc amplification in neuroblastoma: Report of clinical cases

European Journal of Pediatric Surgery

Volumn 9, Issue 3, 1999, Pages 138-141

  Hasan, Z ^a,b   Inoue, A ^b   Ikeda, H ^c   Kamii, Y ^a   Obana, K ^a   Yokomori, K ^a   Tsuchida, Y ^a,c   Hemmi, H ^b   Shimatake, H ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Gunma Children's Medical Center   (Japan)

Author keywords

Fine needle biopsy; N myc gene; Neuroblastoma; PCR; Southern blot hybridization

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; PIRARUBICIN;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; GENE AMPLIFICATION; GENE NUMBER; HUMAN; INFANT; MALE; NEEDLE BIOPSY; NEUROBLASTOMA; ONCOGENE C MYB; POLYMERASE CHAIN REACTION; PROGNOSIS;

EID: 0032814130     PISSN: 09397248     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1072229     Document Type: Article

References (14)

1. Brison O: Gene amplification and tumor progression. Biochim Biophys Acta 1155 (1993) 25-41
2. Brodeur GM: Neuroblastoma: Clinical significance of genetic abnormalities. Cancer Surv 9 (1990) 673-688
3. Brodeur GM, Seeger RC, Schwab M, et al: Amplification of N-myc in untreated human neuroblastomas correlates with advanced stage disease. Science 244 (1984) 1121-1124
4. Cohn S, Salwen H, Quansney NW, et al: Prolonged N-myc protein halflife in a neuroblastoma cell line lacking N-myc amplification. Oncogene 5 (1990) 1821-1827
5. Ikegaki N, Bukovsky J, Kennet RH: Identification and characterization of the N-myc gene product in human neuroblastoma cells by monoclonal antibody with defined specifities. Proc Natl Acad Sci USA 83 (1986) 5929-5933
6. Inoue A, Hasan Z, Hemmi H, et al: Competitive polymerase chain reaction for the quantification of N-myc copy number in neuroblastoma. Tumor Biol 17 (1996) 262-270
7. Ramsy G, Stanton L, Schwab M, et al: Human proto-oncogene N-myc encodes nuclear proteins that bind DNA. Mol Cell Biol 6 (1986) 4450-4457
8. Seeger RC, Brodeur GM, Sather H, et al: Association of multiple copies of N-myc oncogene with rapid tumor progression of neuroblastoma. N Engl J Med 313 (1985) 1111-1116
9. Seeger RC, Wada R, Brodeur GM, et al: Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene. Prog Clin Biol Res 80 (1988) 1633-1637
10. Shimtake H, Nakagawa C, Tsukahara T, et al: A relationship between embryonal and tumor N-myc protein expression as revealed by anti N-myc protein antibody. Clin Chem Enzyme Commun 2 (1990) 227-234
11. Suita S, Zaizen Y, Tsuchida Y, et al: What is the benefit of aggressive chemotherapy for advanced neuroblastoma with N-myc amplification? A report from the Japanese Study Group for the Treatment of Advanced Neuroblastoma. J Pediatr Surg 29 (1994) 746-750
12. Tsuchida Y, Choi SH, Kaneko M: Neuroblastoma: Genetic markers and treatment. Cancer J 8 (1995) 250-254
13. Tsuchida Y, Hemmi H, Inoue A, et al: Genetic clinical markers of human neuroblastoma with special reference to N-myc oncogene: Amplified or not amplified? Tumor Biol 17 (1996) 65-74
14. Tsuchida Y, Kanda N, Shimatake H, et al: Clinical significance of gene amplification studied in human neuroblastoma xenograft: Relationship with tumor growth rate, chemotherapeutic sensitivities and level of neuron-specific enolase. Exp Cell Biol 56 (1988) 277-284