Expression of vitamin D receptor in cultured human keratinocytes and fibroblasts is not altered by corticosteroids

Journal of Dermatological Science

Volumn 21, Issue 1, 1999, Pages 8-12

  Midorikawa, Kazushige ^a   Sayama, Koji ^a   Shirakata, Yuji ^a   Hanakawa, Yasushi ^a   Sun, Ling ^a   Hashimoto, Koji ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

1,25 Dihydroxyvitamin D3; 9A7 ; Clobetasol propionate; Dexamethasone; Vitamin D3; Western blot

Indexed keywords

CALCITRIOL; CLOBETASOL PROPIONATE; CORTICOSTEROID; DEXAMETHASONE; DITHIOTHREITOL; VITAMIN D RECEPTOR;

ARTICLE; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; RECEPTOR DOWN REGULATION;

ADMINISTRATION, TOPICAL; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELLS, CULTURED; CLOBETASOL; DEXAMETHASONE; DOWN-REGULATION; FEMALE; FIBROBLASTS; GLUCOCORTICOIDS; HUMANS; KERATINOCYTES; MALE; MIDDLE AGED; PSORIASIS; RECEPTORS, CALCITRIOL; SKIN;

EID: 0032811736     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-1811(99)00007-9     Document Type: Article

References (17)

1. Morimoto S., Yoshikawa K., Kozuka T., Kitano Y., Imanaka S., Fukuo K., Koh E., Kumahara Y. An open study of vitamin D3 treatment in psoriasis vulgaris. Br J Dermatol. 115:1986;421-429.
2. Kato T., Rokugo M., Terui T., Tagami H. Successful treatment of psoriasis with topical application of active vitamin D3 analogue 1α,24-dihydroxycholecalciferol. Br J Dermatol. 115:1986;431-433.
3. Abe M., Ohnishi K., Warita S., Tamura A., Ishikawa O., Miyachi Y. Topical treatment with tacalcitol ointment for psoriasis vulgaris in Gunma University. Acta Dermatol (Kyoto). 92:1997;395-402. In Japanese.
4. Pike J.W. Vitamin D3 receptors: structure and function in transcription. Annu Rev Nutr. 11:1991;189-216.
5. Baker A.R., McDonnell D.P., Hughes M., Crisp T.M., Mangelsdorf D.J., Haussler M.R., Pike J.W., Shine J., O'Malley B.W. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci USA. 85:1988;3294-3298.
6. Ohyama Y., Ozono K., Uchida M., Shinki T., Kato S., Suda Y., Yamamoto O., Noshiro M., Kato Y. Identification of vitamin responsive elements in the 5′-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene. J Biol Chem. 269:1994;10545-10550.
7. Hashimoto K., Higashiyama S., Asada H., Hashimura E., Kobayashi T., Sudo K., Nakagawa T., Damm D., Yoshikawa K., Taniguchi N. Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J Biol Chem. 269:1994;20060-20066.
8. Solvsten H., Fogh K., Svendsen M., Kristensen P., Astrom A., Kumar R., Kragballe K. Normal levels of the vitamin D receptor and its message in psoriatic skin. J Invest Dermatol Symp Proc. 1:1996;28-32.
9. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:1976;248-254.
10. Maclaughlin J.A., Gange W., Taylor D., Smith E., Holick M.F. Cultured psoriatic fibroblasts from involved and uninvolved sites have a partial but not absolute resistance to the proliferation-inhibitory activity of 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci USA. 82:1985;5409-5412.
11. Hashimoto K., Matsumoto K., Higashiyama M., Nishida Y., Yoshikawa K. Growth-inhibitory effect of 1,25-dihydroxyvitamin D3 on normal and psoriatic keratinocytes. Br J Dermatol. 123:1990;93-98.
12. Holick M.F., Chen M.L., Kong X.F., Sanan D.K. Clinical uses for calciotropic hormones 1,25-dihydroxyvitamin D3 and parathyroid hormone-related peptide in dermatology; A new perspective. J Invest Dermatol Symp Proc. 1:1996;1-9.
13. Valdimarsson H., Baker B.S., Jonsddotir I., Powles A., Fry L. A T-cell-mediated autoimmune disease induced by Staphylococcus superantigen? Immunol Today. 16:1995;145-149.
14. Yu X.P., Mocharla H., Hustmyer F.G., Manolagas S.C. Vitamin D receptor expression in human lymphocytes. J Biol Chem. 266:1991;7588-7595.
15. 3. J Clin Invest. 79:1987;1659-1664.
16. 3 inhibits γ-interferon synthesis by normal human peripheral blood lymphocytes. Proc Natl Acad Sci USA. 84:1987;3385-3389.
17. 3 in normal human peripheral blood lymphocytes. J Clin Invest. 79:1987;1700-1705.