Oxidative damage in fetal rat brain induced by ischemia and subsequent reperfusion

Biology of the Neonate

Volumn 76, Issue 2, 1999, Pages 84-91

  Wakatsuki, Akihiko ^a   Izumiya, Chiaki ^a   Okatani, Yuji ^a   Sagara, Yusuke ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Arachidonic acid; Brain; Fetal rat; Lipid peroxidation; Lipoxygenase

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; LIPOXYGENASE; PHENIDONE; PROSTAGLANDIN SYNTHASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN MITOCHONDRION; CONTROLLED STUDY; FETUS; ISCHEMIA; LIPID BRAIN LEVEL; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; TIME; UTERINE ARTERY;

ANIMALS; ARACHIDONIC ACID; ASPIRIN; BRAIN; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; FEMALE; FETAL DISEASES; ISCHEMIC ATTACK, TRANSIENT; LIPID PEROXIDATION; LIPOXYGENASE INHIBITORS; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PREGNANCY; PYRAZOLES; RATS; RATS, WISTAR; REPERFUSION INJURY; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0032810962     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000014145     Document Type: Article

References (39)

1. Little WJ: On the influences of abnormal parturition, difficult labours, premature birth and asphyxia neonatorum on mental and physical conditions of the child, especially in relation to deformities. Trans Obstet Soc Lond 1862;3:293-344.
2. Blair E, Stanley F: Intrapartum asphyxia: A rare case of cerebral palsy. J Pediatr 1988;112:515-519.
3. Freeman JM, Nelson KB: Intrapartum asphyxia and cerebral palsy. Pediatrics 1988;82:240-249.
4. Nelson KB, Ellenberg H: Antecedents of cerebral palsy: Multiple analysis of risk. N Engl J Med 1986;315: 81-86.
5. Naeye RL, Peters EC, Bartholomew M, Landis JR: Origins of cerebral palsy. AJDC 1989;143:1154-1161.
6. Murphy DJ, Sellers S, MacKenzie IZ, Yudkin PL, Johnson AM: Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babies. Lancet 1995;346:1449-1454.
7. Leviton A: Preterm birth and cerebral palsy: Is tumor necrosis factor the missing link? Dev Med Child Neurol 1993;35:549-558.
8. Levene MI: Cerebral ultrasound and neurological impairment: telling the future. Arch Dis Child 1990;65: 469-471.
9. Iida F, Takashima S, Takeuchi Y: Etiology and distribution of neonatal leukomalacia. Pediatr Neurol 1992;8:205-209.
10. Shaller CA, Jaques S, Shelden CH: The pathophysiology of stroke: A review with molecular considerations. Surg Neurol 1980;14:433-443.
11. Siesjo BK: Cell damage in the brain: A speculative synthesis. J Cereb Blood Flow Metab 1981;14:433-443.
12. Ishii H, Stanimirovic DB, Chang CJ, Mrsulja BB, Spatz M: Dopamine metabolism and free-radical related mitochondrial injury during transient brain ischemia in gerbils. Neurochem Res 1993;18:1193-1201.
13. Mishra OP, Delivoria-Papadopoulos M: Anti-oxidant enzymes in fetal guinea pig brain during development and the effect of maternal hypoxia. Dev Brain Res 1988;42:173-179.
14. Sun D, Kintner D, Fitzpatrick JH, Emoto SE, Braquet PG, Bazan NG, Gilboe DD: The effect of free radical scavenger and platelet-activating factor antagonist on FFA accumulation in post-ischemic canine brain. Neurochem Res 1994;19:525-528.
15. Espinoza MI, Parer JT: Mechanisms of asphyxiai brain damage, and possible pharmacologic interventions, in the fetus. Am J Obstet Gynecol 1991;164:1582-1589.
16. Asano T, Koide T, Gotoh O, Joshita H, Hanamura T, Shigeno T, Takakura K: The role of free radicals and eicosanoids in the pathogenetic mechanism underlying ischemic brain edema. Mol Chem Neuropathol 1989;10:101-133.
17. Baskaya MK, Hu Y, Donaldson D, Maley M, Rao AM, Prasad MR, Dempsey RJ: Protective effect of the 5-lipoxygenase inhibitor AA-861 on cerebral edema after transient ischemia. J Neurosurg 1996;85:112-116.
18. Yamamoto N, Yokota K, Yamashita A, Oda M: Effect of KBT-3022, a new cyclooxygenase inhibitor, on experimental brain edema in vitro and in vivo. Eur J Pharmacol 1996; 297:225-231.
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
20. Chance B. Williams GR: A simple and rapid assay of oxidative phosphorylation. Nature 1955;175: 1120-1121.
21. Chance B, Williams GR: The respiratory chain and oxidative phosphorylation. Adv Enzymol Relat Areas Mol Biol 1956;17:65-134.
22. Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358.
23. Geese A, Ottlecz A, Mezei G, Telegdy G, Joo F, Dux E, Karnushina I: Prostacyclin and prostaglandin synthesis in isolated brain capillaries. Prostaglandins 1982;23:287-297.
24. Blackwell GJ, Flower RJ: 1-phenyl-3-pyrazolidone: An inhibitor of cyclooxygenase and lipoxygenase pathways in lung and platelets. Prostaglandins 1978;16:417-425.
25. Hillered L, Siesjo BK, Arfors K: Mitochondrial response to transient forebrain ischemia and recirculation in the rat. J Cereb Blood Flow Metab 1983;4:438-446.
26. Halliwell B, Gutteridge JMC: Oxygen radicals and the nervous system. Trends Neurosci 1985;8:22-26.
27. Mishra OP, Delivoria-Papadopoulos M: Lipid peroxidation in developing fetal guinea pig brain during normoxia and hypoxia. Dev Brain Res 1984;45:129-135.
28. Drazen JM, Austen KF, Lewis RA, Clark DA, Goto G, Marfat A, Corey EJ: Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci USA 1980;77:4354-4358.
29. Majerus PW: Arachidonate metabolism in vascular disorders. J Clin Invest 1983;72:1521-1525.
30. Abdel-Halim MS, von Holts H, Meyerson B, Sachs C, Anggard E: Prostaglandin profiles in tissue and blood vessels from human brain. J Neurochem 1980;34:1331-1333.
31. Chen J, Weinstein PR, Graham SH: Attenuation of postischemic brain hypoperfusion and reperfusion injury by the cyclooxygenase-lipoxygenase inhibitor BW755C. J Neurosurg 1995;83:99-104.
32. Mishra OP, Kubin JA, McGowan JE, Delivoria-Papadopoulos M: Kainate receptor: Modification in the fetal guinea pig brain during hypoxia. Neurochem Res 1995;20: 1171-1177.
33. Razdan B, Kubin J, Mishra OP, Delivoria-Papadopoulos M: Modification of glycine (co-activator) binding site of the N-methyl-D-aspartate receptor in the guinea pig fetus brain during development following hypoxia. Brain Res 1996;733:15-20.
34. Groenendaal F, Mishra OP, Jane E, McGowan JE, Hoffman DJ, Delivoria-Papadopoulos M: Cytosolic and membrane-bound cerebral nitric oxide synthase activity during hypoxia in cortical tissue of newborn piglets. Neurosci Lett 1996;206:121-124.
35. Kukreja RC, Kontos HA, Hess ML, Ellis EF: PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Circ Res 1986;59:612-619.
36. Egan RW, Paxton J, Kuehl FA: Mechanism for irreversible self-deactivation of prostaglandin synthetase. J Biol Chem 1976;251: 7329-7335.
37. Phillis JW, Sen S, Cao X: Amflutizole, a xanthine oxidase inhibitor, inhibits free radical generation in the ischemia/reperfused rat cerebral cortex. Neurosci Lett 1994;169: 188-190.
38. Hasegawa K, Yoshida H, Sawada T, Nishikawa H: Direct measurement of free radicals in the neonatal mouse brain subjected to hypoxia: An electron spin resonance spectroscopic study. Brain Res 1993;607: 161-166.
39. Oka A, Belliveau MJ, Rosenberg PA, Volpe JJ: Vulnerability of oligodendroglia to glutamate: Pharmacology, mechanisms, and prevention. J Neurosci 1993;13:1441-1453.