Modified gas chromatographic-mass spectrometric assay for the determination of gacyclidine enantiomers in human plasma

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 731, Issue 2, 1999, Pages 317-322

  Hoizey, Guillaume ^a   Baccard, Nathalie ^b   Gourdier, Bertrand ^a   Lamiable, Denis ^b   Millart, Hervé ^b   D'Arbigny, Pierre ^c   Vistelle, Richard ^a  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b HÔPITAL MAISON BLANCHE   (France)

^c IPSEN   (France)

Author keywords

Enantiomer separation; Gacyclidine

Indexed keywords

GACYCLIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ADULT; ANALYTIC METHOD; ARTICLE; BLOOD ANALYSIS; CHIRALITY; DRUG DETERMINATION; DRUG DISTRIBUTION; ENANTIOMER; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

CALIBRATION; CYCLOHEXANES; CYCLOHEXENES; EXCITATORY AMINO ACID ANTAGONISTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; PIPERIDINES; RECEPTORS, N-METHYL-D-ASPARTATE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0032810932     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00252-2     Document Type: Article

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