Analysis of aplidine (dehydrodidemnin B), a new marine-derived depsipeptide, in rat biological fluids by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 731, Issue 2, 1999, Pages 335-343

  Celli, Nicola ^a   Gallardo, Agata Motos ^a   Rossi, Cosmo ^b   Zucchetti, Massimo ^c   D'Incalci, Maurizio ^c   Rotilio, Domenico ^a  

^a g Paone Environ Hlth Ctr   (Italy)

^b Exp Models and Animal Care Unit   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Aplidine; Depsipeptide; Didemnin

Indexed keywords

DEHYDRODIDEMNIN B; DIDEMNIN B;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BODY FLUID; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EXCRETION; EXTRACTION; INTRAVENOUS DRUG ADMINISTRATION; LIQUID CHROMATOGRAPHY; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEPSIPEPTIDES; MALE; MASS SPECTROMETRY; OLIGOPEPTIDES; PEPTIDES, CYCLIC; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS;

EID: 0032810864     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00262-5     Document Type: Article

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