Sequence-specific alkylation of DNA by duocarmycin A and its novel derivatives bearing Py/Im polyamides

Nucleosides and Nucleotides

Volumn 18, Issue 6-7, 1999, Pages 1615-1616

  Tao, Z F ^a   Fujiwara, T ^a   Saito, I ^b,c   Sugiyama, H ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; DUOCARMYCIN A; POLYAMIDE;

CONFERENCE PAPER; DIMERIZATION; DNA ALKYLATION; DRUG DNA BINDING; DRUG EFFECT; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0032809446     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319908044799     Document Type: Conference Paper

References (2)

1. Sugiyama, H.; Lian, C.; Isomura, M.; Saito, I.; Wang, A. H. -J. Proc. Natl. Acad. Sci. USA 1996, 93, 14405.
2. White, S.; Szewczyk, J. W.; Turner, J. M.; Baird, E. E.; Dervan, P. B. Nature 1998, 391, 468.