A Trypanosoma cruzi alkaline antigen induces polyclonal B-cell activation of normal murine spleen cells by T-cell-independent, BCR-directed stimulation

Scandinavian Journal of Immunology

Volumn 50, Issue 2, 1999, Pages 159-166

  Montes, C L ^a   Zuniga E ^a   Minoprio, P ^b   Vottero Cima, E ^a   Gruppi, Adriana ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD40 ANTIGEN; CD45 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLYCOPROTEIN GP 39; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 6; LEUCINE METHYL ESTER; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE; TRYPANOSOMA CRUZI;

ANIMALS; ANTIGENS, CD45; ANTIGENS, PROTOZOAN; B-LYMPHOCYTES; CD40 LIGAND; CELL DIVISION; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOGLOBULIN MU-CHAINS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, INTERLEUKIN-2; SPLEEN; T-LYMPHOCYTES; TRYPANOSOMA CRUZI;

EID: 0032807661     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1999.00577.x     Document Type: Article

References (32)

1. 1 Minoprio P, Eisen H, Forni L, D'Imperio-Lima MR, Joskowicz M, Coutinho A. Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T and B cell responses. Scand J Immunol 1986;24:661-8.
2. 2 D'Imperio-Lima MR, Joskowicz M, Coutinho A, Kipnis T, Eisen H. Very large and isotypically atypical polyclonal plaque-forming cell responses in mice infected with Trypanosoma cruzi. Eur J Immunol 1986;15:201-3.
3. 3 D'Imperio-Lima MR, Eisen H, Minoprio P, Joskowicz M, Coutinho A. Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease. J Immunol 1986;137:353-6.
4. 4 Minoprio P, Burlen O, Pereira P et al. Most B cells in acute Trypanosoma cruzi infection lack parasite specificity. Scand J Immunol 1988;28:553-1.
5. 5 Minoprio P, Coutinho A, Joskowicz M, D'Imperio-Lima MR, Eisen H. Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. II. Cytotoxic T lymphocytes. Scand J Immunol 1986;24:669-79.
6. 6 Minoprio P, Eisen H, Joskowicz M, Pereira P, Coutinho A. Suppression of polyclonal antibody production in Trypanosoma cruzi infected mice by treatment with anti-L3T4 antibodies. J Immunol 1987;139:545-50.
7. 7 Goldenberg SS, Carneiro MN, Silva-Pereira AA, Mares-Guia L. Release of lipopolysaccharide (LPS) from the cell surface of Trypanosoma cruzi by EDTA. Int J Parasitol 1983;13:11-8.
8. 8 Cordeiro Da Silva A, Espinoza AG, Taibi A, Ouaissi A, Minoprio P. A 24000 MW Trypanosoma cruzi antigen is a B-cell activator. Immunology 1998;94:189-96.
9. 9 Montes CL, Vottero-Cima E, Gruppi A. Trypanosoma cruzi cytosolic alkaline antigens (FI) induce polyclonal activation in murine normal B cells. Scand J Immunol 1996;44:93-100.
10. 10 Rott O, Cash E. Influenza virus hemagglutinin induces differentiation of mature resting B cells and growth arrest of immature WEHI-231 lymphoma cells. J Immunol 1994;152:5381-91.
11. 11 Hillman K, Shapira-Nahor O, Black-Burn R, Hernandez D, Golding H. A polymer containing a repeating peptide sequence can stimulate T-cell independent IgG antibody production in vivo. Cell Immunol 1991;134:1-13.
12. 12 Freudenberg MA, Galanos C. Bacterial lipopolysaccharide: structure, metabolism and mechanisms of action. Int Rev Immunol 1990; 6:207-21.
13. 13 Wetzel GD, Swain SL, Dutton RW, Kettman JR. Evidence for two distinct activation states available to B lymphocytes. J Immunol 1984;133:2327-32.
14. 14 Watanabe K, Kumada H, Yoshimura F, Umemoto T. The induction of polyclonal B-cell activation and interleukin-1 production by the 75-kDa cell surface protein from Porphyromonas gingivalis in mice. Arch Oral Biol 1996;41:725-31.
15. 15 Lipford GB, Sparwasser T, Bauer M et al. Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines. Eur J Immunol 1997;27:3420-6.
16. 16 Camargo EP. Growth and differentiation in T. cruzi. I. Origin of metacyclic trypanosomes in liquid media. Rev Med Trop S Paulo 1964;6:93-7.
17. 17 Thiele DL, Kurosawa M, Lipsky P. Phenotype of the accessory cell neccessary for mitogen stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester. J Immunol 1983;131:2282-90.
18. 18 Kim KM, Albert G, Weiser P, Reth M. Signalling function of the B-cell antigen receptor. Immunol Rev 1993;132:125-46.
19. 19 Gruber MF, Bjorndahl JM, Nakamura S, Man Fu S. Anti-CD45 inhibition of human B cell proliferation depends on the nature of activation signals and the state of B cell activation. J Immunol 1989;142:4144-8.
20. 20 Forsgren S, Pobor G, Coutinho A, Pierres M. The role of IA/IE molecules in B lymphocyte activation. I. Inhibition of lipopolysaccharide-induced responses by monoclonal antibodies. J Immunol 1984;133:2104-10.
21. 21 Noelle RJ, Roy M, Shepherd D, Atamenkovic I, Ledbetter JA, Aruffo A. A 39-kDa protein on activated T cells binds CD40 and transduces the signal tor cognate activation of B cells. Proc Natl Acad Sci USA 1992;89:6550-4.
22. 22 Xu J, Foy TM, Laman JD et al. Mice deficient for CD40 ligand. Immunity 1994;1:423-31.
23. 23 Wykes M, Poudrier J, Lindstedt R, Gray D. Regulation of cytoplasmic, surface and soluble forms of CD40 ligand in mouse B cells. Eur J Immunol 1998;28:548-59.
24. 24 Michael A, Hackett JJ, Bennett M, Kumar V, Yuan D. Regulation of B lymphocytes by NK cells: role of INF-γ. J Immunol 1989;142:1095-101.
25. 25 Snapper CM, Mond JJ. Towards a comprehensive view of immunoglobulin class switching. Immunol Today 1993;14:15-7.
26. 26 Kouskoff V, Famiglietti S, Lacaud G et al. Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. J Exp Med 1998;188:1453-64.
27. 27 Justement LB, Campbell KS, Chien NC, Cambier JC. Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45. Science 1991;252:1839-42.
28. 28 Grammer AC, Bergman MC, Miura Y, Fujita K, Davis LS, Lipsky PE. The CD40 ligand expressed by human B cells costimulates B cell responses. J Immunol 1995;154:4996-5010.
29. 29 Grauert A, Houdayer M, Hontebeyrie-Josckowicz M. Trypanosoma cruzi infection enhances polyreactive antibody response in an acute case of human Chagas' disease. Clin Exp Immunol 1993;93: 85-92.
30. 30 Unterkircher C, Avrameas S, Ternynck T. Autoantibodies in sera of Trypanasoma cruzi-infected individuals with or without clinical Chagas' disease. J Clin Lab Analysis 1993;7:60-9.
31. 31 Ternynck T, Bleux C, Gregoire J, Avrameas S, Kanellopoulos-Langevin C. Comparison between autoantibodies arising during T. cruzi infection and natural autoantibodies. J Immunol 1990;144:1504-11.
32. 32 Gazzinelli RT. Natural anti-Gal antibodies prevent, rather than cause, autoimmunity in human Chagas's disease. Res Immunol 1991;142:164-7.