메뉴 건너뛰기




Volumn 177, Issue 4, 1999, Pages 219-228

Budesonide down-regulates eosinophil locomotion but has no effects on ECP release or on H2O2 production

Author keywords

Allergic asthma; Chemotaxis; Corticosteroids; Cytokines; Granulocytes; Interleukin 5; T lymphocytes

Indexed keywords

BUDESONIDE; EOSINOPHIL CATIONIC PROTEIN; HYDROGEN PEROXIDE; INTERLEUKIN 5;

EID: 0032806919     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00007642     Document Type: Article
Times cited : (7)

References (42)
  • 1
    • 0025374344 scopus 로고
    • Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage: The effects of anti-asthmatic treatment with budesonide or terbutaline
    • 1. Adelroth E, Rosenthall L, Johansson S-A, Linden M, Venge P (1990) Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage: the effects of anti-asthmatic treatment with budesonide or terbutaline. Am Rev Respir Dis 142:91-99
    • (1990) Am Rev Respir Dis , vol.142 , pp. 91-99
    • Adelroth, E.1    Rosenthall, L.2    Johansson, S.-A.3    Linden, M.4    Venge, P.5
  • 2
    • 0029759168 scopus 로고    scopus 로고
    • Mechanism of actions of glucocorticoids in asthma
    • 2. Barnes PJ (1996) Mechanism of actions of glucocorticoids in asthma. Am J Respir Crit Care Med 154:S21-S27
    • (1996) Am J Respir Crit Care Med , vol.154
    • Barnes, P.J.1
  • 3
    • 0027494730 scopus 로고
    • Anti-inflammatory actions of steroids: Molecular mechanisms
    • 3. Barnes PJ, Adcock IM (1993) Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol Sci 14:436-441
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 436-441
    • Barnes, P.J.1    Adcock, I.M.2
  • 4
    • 0026875146 scopus 로고
    • Airway eosinophils and lymphocytes in asthma: Birds of a feather?
    • 4. Berkman JS, Weller PF (1992) Airway eosinophils and lymphocytes in asthma: birds of a feather? Am Rev Respir Dis 145:1246-1248
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1246-1248
    • Berkman, J.S.1    Weller, P.F.2
  • 6
    • 0025836972 scopus 로고
    • Indirect evidence of bronchial inflammatory mediators in BAL fluid of patients with asthma
    • 6. Bousquet J, Chanez P, Lacoste JY, et al. (1991) Indirect evidence of bronchial inflammatory mediators in BAL fluid of patients with asthma. J Allergy Clin Immunol 88:649-660
    • (1991) J Allergy Clin Immunol , vol.88 , pp. 649-660
    • Bousquet, J.1    Chanez, P.2    Lacoste, J.Y.3
  • 7
    • 0025667042 scopus 로고
    • Allergen-induced increases in airways responsiveness and inflammation in mild asthma
    • 7. Brusasco V, Crimi E, Gianiorio P, Lantero S, Rossi GA (1990) Allergen-induced increases in airways responsiveness and inflammation in mild asthma. J Appl Physiol 69:2209-2214
    • (1990) J Appl Physiol , vol.69 , pp. 2209-2214
    • Brusasco, V.1    Crimi, E.2    Gianiorio, P.3    Lantero, S.4    Rossi, G.A.5
  • 8
    • 0022638242 scopus 로고
    • Oxidant-mediated ciliary dysfunction: Possible role in airway disease
    • 8. Burman WJ, Martin WJ II (1986) Oxidant-mediated ciliary dysfunction: possible role in airway disease. Chest 89:410-413
    • (1986) Chest , vol.89 , pp. 410-413
    • Burman, W.J.1    Martin W.J. II2
  • 9
    • 0024591512 scopus 로고
    • Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GMCSF
    • 9. Clutterbuck EJ, Hirst EMA, Sanderson CJ (1989) Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GMCSF. Blood 73:1504-1510
    • (1989) Blood , vol.73 , pp. 1504-1510
    • Clutterbuck, E.J.1    Hirst, E.M.A.2    Sanderson, C.J.3
  • 10
    • 0026443197 scopus 로고
    • T-cells and eosinophils in the pathogenesis of asthma
    • 10. Corrigan C, Kay AB (1992) T-cells and eosinophils in the pathogenesis of asthma. Immunol Today 13:501-507
    • (1992) Immunol Today , vol.13 , pp. 501-507
    • Corrigan, C.1    Kay, A.B.2
  • 11
    • 0026590451 scopus 로고
    • Effects of an inhaled corticosteroid on airway inflammation and symptoms in asthma
    • 11. Djukanovic R, Wilson JW, Britten KM, Holgate S (1992) Effects of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis 145:669-674
    • (1992) Am Rev Respir Dis , vol.145 , pp. 669-674
    • Djukanovic, R.1    Wilson, J.W.2    Britten, K.M.3    Holgate, S.4
  • 12
    • 85004809844 scopus 로고
    • Eosinophils, bronchial hyperreactivity and late phase asthmatic reactions
    • 12. Durham SR, Kay AB (1985) Eosinophils, bronchial hyperreactivity and late phase asthmatic reactions. Clin Allergy 15:411-418
    • (1985) Clin Allergy , vol.15 , pp. 411-418
    • Durham, S.R.1    Kay, A.B.2
  • 14
    • 0018646361 scopus 로고
    • The effect of hydrocortisone on superoxide production by leukocytes
    • 14. Fuenfer MM, Carr EA, Polk HC (1979) The effect of hydrocortisone on superoxide production by leukocytes. J Surg Res 27:29-35
    • (1979) J Surg Res , vol.27 , pp. 29-35
    • Fuenfer, M.M.1    Carr, E.A.2    Polk, H.C.3
  • 15
    • 0018834859 scopus 로고
    • Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium
    • 15. Fugas E, Loegerring DA, Gleich GL (1980) Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium. Lab Invest 42:35-43
    • (1980) Lab Invest , vol.42 , pp. 35-43
    • Fugas, E.1    Loegerring, D.A.2    Gleich, G.L.3
  • 16
    • 0018859803 scopus 로고
    • Separation of human eosinophils in density gradients of polyvinylpyrrolidone-coated silica gel (Percoll)
    • 16. Gartner I (1980) Separation of human eosinophils in density gradients of polyvinylpyrrolidone-coated silica gel (Percoll). Immunology 40:133-136
    • (1980) Immunology , vol.40 , pp. 133-136
    • Gartner, I.1
  • 18
    • 0026606394 scopus 로고
    • Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma
    • 18. Jeffery PK, Godfrey RW, Adelroth E, Nelson F, Rogers A, Johansson A (1992) Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. Am Rev Respir Dis 145:890-899
    • (1992) Am Rev Respir Dis , vol.145 , pp. 890-899
    • Jeffery, P.K.1    Godfrey, R.W.2    Adelroth, E.3    Nelson, F.4    Rogers, A.5    Johansson, A.6
  • 19
    • 0025900437 scopus 로고
    • Asthma and inflammation
    • 19. Kay AB (1991) Asthma and inflammation. J Allergy Clin Immunol 87:893-910
    • (1991) J Allergy Clin Immunol , vol.87 , pp. 893-910
    • Kay, A.B.1
  • 20
    • 0023554640 scopus 로고
    • Bronchoalveolar lavage cell profiles of asthmatic and nonasthmatic subjects
    • 20. Kirby JG, Hargrave FE, Gleich GJ, O'Byrne PM (1987) Bronchoalveolar lavage cell profiles of asthmatic and nonasthmatic subjects. Am Rev Respir Dis 136:379-383
    • (1987) Am Rev Respir Dis , vol.136 , pp. 379-383
    • Kirby, J.G.1    Hargrave, F.E.2    Gleich, G.J.3    O'Byrne, P.M.4
  • 22
    • 0029943913 scopus 로고    scopus 로고
    • Eosinophil locomotion and the release of IL-3 and IL-5 by allergen-stimulated mononuclear cells are effectively downregulated "in vitro" by budesonide
    • 22. Lantero S, Sacco O, Scala C, Spallarossa D, Rossi GA (1996) Eosinophil locomotion and the release of IL-3 and IL-5 by allergen-stimulated mononuclear cells are effectively downregulated "in vitro" by budesonide. Clin Exp Allergy 26:656-664
    • (1996) Clin Exp Allergy , vol.26 , pp. 656-664
    • Lantero, S.1    Sacco, O.2    Scala, C.3    Spallarossa, D.4    Rossi, G.A.5
  • 23
    • 0030933066 scopus 로고    scopus 로고
    • Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotactic activity that includes IL-3, IL-5, and GM-CSF
    • 23. Lantero S, Sacco O, Scala C, Spallarossa D, Rossi GA (1997) Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotactic activity that includes IL-3, IL-5, and GM-CSF. J Asthma 34:141-152
    • (1997) J Asthma , vol.34 , pp. 141-152
    • Lantero, S.1    Sacco, O.2    Scala, C.3    Spallarossa, D.4    Rossi, G.A.5
  • 24
    • 0028324365 scopus 로고
    • Effects of a corticosteroid, budesonide, on alveolar macrophage and blood monocyte secretion of cytokines: Differential sensitivity of GM-CSF, IL-1b, and IL-6
    • 24. Linden M, Brattsand R (1994) Effects of a corticosteroid, budesonide, on alveolar macrophage and blood monocyte secretion of cytokines: differential sensitivity of GM-CSF, IL-1b, and IL-6. Pulm Pharmacol 7:43-47
    • (1994) Pulm Pharmacol , vol.7 , pp. 43-47
    • Linden, M.1    Brattsand, R.2
  • 25
    • 0028224144 scopus 로고
    • Effects of fluticasone propionate on neutrophil chemotaxis, superoxide generation, and extracellular proteolytic activity in vitro
    • 25. Llewellyn-Jones CG, Hill SL, Stockley RA (1994) Effects of fluticasone propionate on neutrophil chemotaxis, superoxide generation, and extracellular proteolytic activity in vitro. Thorax 49:207-212
    • (1994) Thorax , vol.49 , pp. 207-212
    • Llewellyn-Jones, C.G.1    Hill, S.L.2    Stockley, R.A.3
  • 26
    • 0022069558 scopus 로고
    • Late asthmatic responses: Inquiry into mechanisms and significance
    • 26. Metzeger WJ, Hunninghake GW, Richerson HB (1985) Late asthmatic responses: inquiry into mechanisms and significance. Clin Rev Allergy 3:145-165
    • (1985) Clin Rev Allergy , vol.3 , pp. 145-165
    • Metzeger, W.J.1    Hunninghake, G.W.2    Richerson, H.B.3
  • 27
    • 0029945410 scopus 로고    scopus 로고
    • Airway eosinophilic inflammation, epithelial damage, and bronchial hyperresponsiveness in patients with mild-moderate stable asthma
    • 27. Oddera S, Silvestri M, Balbo A, Jovovich BO, Penna R, Crimi E, Rossi GA (1996) Airway eosinophilic inflammation, epithelial damage, and bronchial hyperresponsiveness in patients with mild-moderate stable asthma. Allergy 51:100-107
    • (1996) Allergy , vol.51 , pp. 100-107
    • Oddera, S.1    Silvestri, M.2    Balbo, A.3    Jovovich, B.O.4    Penna, R.5    Crimi, E.6    Rossi, G.A.7
  • 28
    • 0028484523 scopus 로고
    • N-acetylcysteine in vitro stimulates phagocytosis and intracellular killing of Staphylococcus aureus by human polymorphonuclear leukocytes and by alveolar macrophages and provides self-killing protection
    • 28. Oddera S, Silvestri M, Sacco O, Eftimiadi C, Crimi E, Brusasco V, Rossi GA (1994) N-Acetylcysteine in vitro stimulates phagocytosis and intracellular killing of Staphylococcus aureus by human polymorphonuclear leukocytes and by alveolar macrophages and provides self-killing protection. J Lab Clin Med 124:293-301
    • (1994) J Lab Clin Med , vol.124 , pp. 293-301
    • Oddera, S.1    Silvestri, M.2    Sacco, O.3    Eftimiadi, C.4    Crimi, E.5    Brusasco, V.6    Rossi, G.A.7
  • 29
    • 0029055474 scopus 로고
    • In vitro effects of "systemic" budesonide on the allergen-induced activation of blood mononuclear cells isolated from asthmatic patients
    • 29. Oddera S, Silvestri M, Sacco O, Lantero S, Morelli MC, Rossi GA (1995) In vitro effects of "systemic" budesonide on the allergen-induced activation of blood mononuclear cells isolated from asthmatic patients. Allergy 50:397-404
    • (1995) Allergy , vol.50 , pp. 397-404
    • Oddera, S.1    Silvestri, M.2    Sacco, O.3    Lantero, S.4    Morelli, M.C.5    Rossi, G.A.6
  • 30
    • 0026876657 scopus 로고
    • Airway hyperresponsiveness, increased intercellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in asthma
    • 30. Ohashi Y, Motojima S, Fukuda T, Makino S (1992) Airway hyperresponsiveness, increased intercellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in asthma. Am Rev Respir Dis 145:1469-1478
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1469-1478
    • Ohashi, Y.1    Motojima, S.2    Fukuda, T.3    Makino, S.4
  • 31
    • 0030958324 scopus 로고    scopus 로고
    • Effects of short term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: A placebo-controlled study
    • 31. Olivieri D, Chetta A, Del Donno M, Bertorelli G, Casalini A, Pesci A, Testi R, Foresi A (1997) Effects of short term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. Am J Respir Crit Care Med 155:1864-1871
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1864-1871
    • Olivieri, D.1    Chetta, A.2    Del Donno, M.3    Bertorelli, G.4    Casalini, A.5    Pesci, A.6    Testi, R.7    Foresi, A.8
  • 32
    • 0026041991 scopus 로고
    • Aerosol steroids as primary treatment of mild asthma
    • 32. Reed CE (1991) Aerosol steroids as primary treatment of mild asthma. N Engl J Med 325:425-426
    • (1991) N Engl J Med , vol.325 , pp. 425-426
    • Reed, C.E.1
  • 33
    • 0027183057 scopus 로고
    • Prednisone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-γ cytokine gene expression
    • 33. Robinson D, Hamid Q, Ying S, et al. (1993) Prednisone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-γ cytokine gene expression. Am Rev Respir Dis 148:401-406
    • (1993) Am Rev Respir Dis , vol.148 , pp. 401-406
    • Robinson, D.1    Hamid, Q.2    Ying, S.3
  • 34
    • 0009567968 scopus 로고
    • 2 production and cytotoxic activity of peripheral blood human eosinophils following stimulation with IgG and IgE immune complexes
    • 2 production and cytotoxic activity of peripheral blood human eosinophils following stimulation with IgG and IgE immune complexes. Prog Respir Res 24: 40-45
    • (1990) Prog Respir Res , vol.24 , pp. 40-45
    • Rossi, G.A.1    Sacco, O.2    Lantero, S.3
  • 35
    • 0025067444 scopus 로고
    • Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma
    • 35. Schleimer RP (1990) Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma. Am Rev Respir Dis 141:S59-S69
    • (1990) Am Rev Respir Dis , vol.141
    • Schleimer, R.P.1
  • 36
    • 0026755576 scopus 로고
    • Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects
    • 36. Sehmi R, Wardlaw AJ, Cromwell O, Kurihara K, Waltmann P, Kay AB (1992) Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood 79:2952-2959
    • (1992) Blood , vol.79 , pp. 2952-2959
    • Sehmi, R.1    Wardlaw, A.J.2    Cromwell, O.3    Kurihara, K.4    Waltmann, P.5    Kay, A.B.6
  • 37
    • 0025857502 scopus 로고
    • Intracellular pH regulates the production of different oxygen metabolites in neutrophils: Effects of organic acids produced by anaerobic bacteria
    • 37. Tonetti M, Cavallero A, Botta GA, Niederman R, Eftimiadi C (1991) Intracellular pH regulates the production of different oxygen metabolites in neutrophils: effects of organic acids produced by anaerobic bacteria. Leukocyte Biol 49:180-188
    • (1991) Leukocyte Biol , vol.49 , pp. 180-188
    • Tonetti, M.1    Cavallero, A.2    Botta, G.A.3    Niederman, R.4    Eftimiadi, C.5
  • 40
    • 0025841768 scopus 로고
    • Glucocorticoids inhibit cytokine-mediated eosinophil survival
    • 40. Wallen N, Kita H, Weiller D, Gleich GJ (1991) Glucocorticoids inhibit cytokine-mediated eosinophil survival. J Immunol 147:3490-3495
    • (1991) J Immunol , vol.147 , pp. 3490-3495
    • Wallen, N.1    Kita, H.2    Weiller, D.3    Gleich, G.J.4
  • 41
    • 0025856894 scopus 로고
    • Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3
    • 41. Warringa RAJ, Koendermann L, Kok PTM, Kreukniet J, Bruijinzeel PBL (1991) Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3. Blood 77:2694-2700
    • (1991) Blood , vol.77 , pp. 2694-2700
    • Warringa, R.A.J.1    Koendermann, L.2    Kok, P.T.M.3    Kreukniet, J.4    Bruijinzeel, P.B.L.5
  • 42
    • 0028534904 scopus 로고
    • Allergen-induced changes in bone marrow progenitors and airway hyperresponsiveness in dogs and the effect of inhaled budesonide on these parameters
    • 42. Woolley MJ, Denburg JA, Ellis R, Dahlback M, O'Byrne PM (1994) Allergen-induced changes in bone marrow progenitors and airway hyperresponsiveness in dogs and the effect of inhaled budesonide on these parameters. Am J Respir Cell Mol Biol 11:600-606
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 600-606
    • Woolley, M.J.1    Denburg, J.A.2    Ellis, R.3    Dahlback, M.4    O'Byrne, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.