Captopril lowers coronary venous free radical concentration after direct current cardiac shocks

Chest

Volumn 116, Issue 2, 1999, Pages 484-487

  Pagan Carlo, Luis A ^a   Garcia, Lawrence A ^a   Hutchison, Joseph L ^a   Buettner, Garry R ^a   Kerber, Richard E ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Angiotensin converting enzyme inhibitors; Captopril; Cardioversion; Defibrillation; Free radicals

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CAPTOPRIL; CATALASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FREE RADICAL; SCAVENGER; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOGENIC SHOCK; CONTROLLED STUDY; CORONARY VEIN; DIRECT CURRENT; DOG; ELECTRON SPIN RESONANCE; EPICARDIUM; FEMALE; HEART MUSCLE INJURY; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032806686     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.116.2.484     Document Type: Article

References (31)

1. Kerber RE, Martins JB, Gascho JA, et al. Effect of direct-current countershocks on regional myocardial contractility and perfusion. Circulation 1981; 63:323-332
2. Dahl CF, Ewy GA, Warner ED, et al. Myocardial necrosis from direct current countershock: effect of paddle electrode size and time interval between discharges. Circulation 1974; 50:956-961
3. Jackson CV, Mickelson JK, Stinger K, et al. Electrolysis-induced myocardial dysfunction: a novel method for the study of free radical mediated tissue injury. J Pharmacol Methods 1986; 15:305-320
4. Trouton TG, Allen JD, Yong LK, et al. Metabolic changes and mitochondrial dysfunction early following transthoracic counter-shocks in dogs. Pacing Clin Electrophysiol 1989; 12:1827-1834
5. Caterine MR, Spencer KT, Pagan-Carlo LA, et al. Direct current countershocks generate free radicals: an electron paramagnetic resonance study. J Am Coll Cardiol 1996; 28:1598-1609
6. Sharma MK, Buettner GR, Kerber RE. Angiotensin converting enzyme inhibitors reduce free radical generation during post-ischemic reperfusion of canine myocardium: a real time study by electron spin resonance spectroscopy [abstract]. J Am Coll Cardiol 1993; 21:410A
7. Chopra M, McMurray J, Stewart J, et al. Free radical scavenging: a potentially beneficial action of thiol-containing angiotensin converting enzyme inhibitors. Biochem Soc Trans 1990; 18:1184-1185
8. Przyklenk K, Kloner RA. Angiotensin converting enzyme inhibitors improve contractile function of stunned myocardium by different mechanisms of action. Am Heart J 1991; 121:1319-1330
9. Mehta JL, Nicolini FA, Dawson DL. Sulfhydryl group in angiotensin converting enzyme inhibitors and superoxide radical formation. J Cardiovasc Pharmacol 1990; 16:847-849
10. Sharma MK, Buettner GR, Spencer KT, et al. Ascorbyl free radical as a real-time marker of free radical generation in briefly ischemic and reperfused hearts: an electron paramagnetic resonance study. Circ Res 1994; 74:650-658
11. Bielski BH. Chemistry of ascorbic acid radicals. In: Seib PA, Tolbert BM, eds. Ascorbic acid: chemistry, metabolism and uses, advances in chemistry series 200. Washington, DC: American Chemical Society, 1982; 81
12. Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol, and ascorbate. Arch Biochem Biophys 1993; 300:535-543
13. Frei B, Stocker R, Ames BN. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci USA 1988; 85:9748-9752
14. Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human plasma. Proc Natl Acad Sci USA 1989; 86:6377-6381
15. Buettner GR, Jurkiewicz BA. Ascorbate free radical as a marker of oxidative stress: an EPR study. Free Radic Biol Med 1993; 14:49-55
16. Buettner GR, Kiminyo KP. Optimal EPR detection of weak nitroxide spin adduct and ascorbyl free radical signals. J Biochem Biophys Methods 1992; 24:147-151
17. Pansegrau DG, Abboud FM. Hemodynamic effects of ventricular defibrillation. J Clin Invest 1970; 49:282-297
18. Przyklenk K, Kloner RA. Acute effects of hydralazine and enalapril on contractile function of post ischemic "stunned" myocardium. Am J Cardiol 1987; 60:934-936
19. Sweet CS. Pharmacologic properties of the converting enzyme inhibitor, enalapril maleate (MK-421). Fed Proc 1983; 42:167-170
20. Koerner JE, Anderson BA, Dage RC. Protection against post ischemic myocardial dysfunction in anesthetized rabbits with scavengers of oxygen-derived free radicals: superoxide dismutase plus catalase, N-2-mercaptopropionyl glycine and captopril. J Cardiovasc Pharmacol 1991; 17:185-191
21. Westlin W, Mullane K. Does captopril attenuate reperfusion-induced myocardial dysfunction by scavenging free radicals? Circulation 1988; 77:130-139
22. Van Vleet JF, Tacker WA. Cardiac damage from transchest and ICD defibrillator shocks. In: Tacker WA Jr, ed. Defibrillation of the heart ICDs, AEDS, and manuals. St. Louis, MO: Mosby, 1994; 259-298
23. Weaver WD, Cobb LA, Copass MK, et al. Ventricular defibrillation: a comparative trial using 175-J and 320-J shocks. N Engl J Med 1982; 307:1101-1106
24. Fatkin D, Kuchar DL, Thorburn CW, et al. Transesophageal echocardiography before and during direct current cardioversion of atrial fibrillation: evidence for atrial stunning as a mechanism of thromboembolic complications. J Am Coll Cardiol 1994; 23:307-316
25. Loesser KE, Kukreja RC, Kazziha SY, et al. Oxidative damage to the myocardium: a fundamental mechanism of myocardial injury. Cardioscience 1991; 2:199-216
26. Myers ML, Bolli R, Lekich RF, et al. Enhancement of recovery of myocardial function by oxygen free radical scavengers after reversible regional ischemia. Circulation 1985; 72:915-921
27. Bolli R, Jeroudi MO, Patel BS, et al. Direct evidence that oxygen-derived free radicals contribute to post-ischemic myocardial dysfunction in the intact dog. Proc Natl Acad Sci USA 1989; 86:4695-4699
28. Jolly SR, Kane WJ, Bailie MB, et al. Canine myocardial reperfusion injury: its reduction by the combined administration of superoxide dismutase and catalase. Circ Res 1984; 54:277-285
29. Bolli R, Patel BS, Jeroudi MO, et al. Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap α-phenyl N-tert-butyl nitrone. J Clin Invest 1988; 82:476-485
30. Bagchi D, Prasad R, Das DK. Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor. Biochem Biophys Res Comm 1982; 158:52-57
31. Mira ML, Silva MM, Manso CF. The scavenging of oxygen free radicals by angiotensin converting enzyme inhibitors: the importance of the sulfhydryl group in the chemical structure of the compounds. Ann NY Acad Sci 1994; 723:439-441