Legionella pneumophila invasion of MRC-5 cells induces tyrosine protein phosphorylation

Infection and Immunity

Volumn 67, Issue 9, 1999, Pages 4490-4498

  Susa, Milorad ^a   Marre, Reinhard ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYCLOHEXIMIDE; GENISTEIN; TUBULIN; VIMENTIN;

ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL GROWTH; CELL ADHESION; CELL INVASION; CYTOSKELETON; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; LUNG FIBROBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0032806048     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.9.4490-4498.1999     Document Type: Article

References (39)

1. Andreev, J., Z. Borovsky, I. Rosenshine, and S. Rottem. 1995. Invasion of HeLa cells by Mycoplasma penetrans and the induction of tyrosine phosphorylation of a 145-kDa host cell protein. FEMS Microbiol. Lett. 132:189-194.
2. Birkelund, S., H. Johnsen, and G. Christiansen. 1994. Chlamydia trachomatis serovar L2 induces protein tyrosine phosphorylation during uptake by HeLa cells. Infect. Immun. 62:4900-4908.
3. Bliska, J. B., and S. Falkow. 1993. The role of host tyrosine phosphorylation in bacterial pathogenesis. Trends Genet. 9:85-89.
4. Brundage, R. A., G. A. Smith, A. Camilli, J. A. Theriot, and D. A. Portnoy. 1993. Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells. Proc. Natl. Acad. Sci. USA 90:11890-11894.
5. Burmer, G. C., P. S. Rabinovitch, and T. H. Norwood. 1984. Evidence for differences in the mechanism of cell cycle arrest between senescent and serum-deprived human fibroblasts: heterokaryon and metabolic inhibitor studies. J. Cell. Physiol. 118:97-103.
6. Cortay, J. C., B. Duclos, and A. J. Cozzone. 1986. Phosphorylation of an Escherichia coli protein at tyrosine. J. Mol. Biol. 187:305-308.
7. Coxon, P. Y., J. T. Summersgill, J. A. Ramirez, and R. D. Miller. 1998. Signal transduction during Legionella pneumophila entry into human monocytes. Infect. Immun. 66:2905-2913.
8. Cozzone, A. J. 1988. Protein phosphorylation in prokaryotes. Annu. Rev. Microbiol. 42:97-125.
9. Cozzone, A. J, 1993. ATP-dependent protein kinases in bacteria. J. Cell. Biochem. 51:7-13.
10. Dadssi, M., and A. J. Cozzone. 1990. Evidence of protein-tyrosine kinase activity in the bacterium Acinetobacter calcoaceticus. J. Biol. Chem. 265: 20996-20999.
11. Daisy, J. A., C. E. Benson, J. McKitrick, and H. M. Friedman. 1981 Intracellular replication of Legionella pneumophila. J. Infect. Dis. 143:460-464.
12. Ensgraber, M., and M. Loos. 1992. A 66-kilodalton heat shock protein of Salmonella typhimurium is responsible for binding of the bacterium to intestinal mucus. Infect. Immun. 60:3072-3078.
13. Farris, M., A. Grant, T. B. Richardson, and C. D. O'Connor. 1998. BipA: a tyrosine-phosphorylated GTPase that mediates interactions between enteropathogenic Escherichia coli (EPEC) and epithelial cells. Mol. Microbiol. 28:265-279.
14. Fawaz, F. S., C. van Ooij, E. Homola, S. C. Mutka, and J. N. Engel. 1997. Infection with Chlamydia trachomatis alters the tyrosine phosphorylation and/or localization of several host cell proteins including cortactin. Infect. Immun. 65:5301-5308.
15. Finlay, B. B., and S. Falkow, 1988. Virulence factors associated with Salmonella species. Microbiol. Sci. 5:324-328.
16. Gao, L.-V., B. J. Stone, J. K. Brieland, and Y. Abu Kwaik. 1998. Different fates of Legionella pneumophila pmi and mil mutants within macrophages and alveolar epithelial cells. Microb. Pathog. 25:291-306.
17. Hanks, S. K., M. B. Calalb, M. C. Harper, and S. K. Patel. 1992 Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc. Natl. Acad. Sci. USA 89:8487-8491.
18. Henke, M., and K. M. Seidel. 1986. Association between Legionella pneumophila and amoebae in water. Isr. J. Med. Sci. 22:690-695.
19. Hess, J. F., R. B. Bourret, and M. I. Simon. 1988. Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis. Nature 336:139-143.
20. Hoffman, P. S., C. A. Butler, and F. D. Quinn. 1989. Cloning and temperature-dependent expression in Escherichia coli of a Legionella pneumophila gene coding for a genus-common 60-kilodalton antigen. Infect. Immun. 57:1731-1739.
21. Hoffman, P. S., M. Ripley, and R. Weeratna. 1992. Cloning and nucleotide sequence of a gene (ompS) encoding the major outer membrane protein of Legionella pneumophila. J. Bacteriol. 174:914-920.
22. Kelly-Wintenberg, K., T. Anderson, and T. C. Montie. 1990. Phosphorylated tyrosine in the flagellum filament protein of Pseudomonas aemginosa. J. Bacteriol. 172:5135-5139.
23. Kenny, B., R. DeVinney, M. Stein, D. J. Reinscheid, E. A. Frey, and B. B. Finlay. 1997. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91:511-520.
24. Leger, I., F. Giroud, and G. Brugal. 1990. Quantitative analysis of cytoskeletal proteins throughout the cell cycle of the MRC-5 fibroblastic cell line. Anal. Quant. Cytol. Histol. 12:321-326.
25. Maruta, K., M. Ogawa, H. Miyamoto, K. Izu, and S. I. Yoshida. 1998. Entry and intracellular localization of Legionella dumoffii in Vero cells. Microb. Pathog. 24:65-73.
26. McDade, J. E., C. C. Shepard, D. W. Fraser, T. R. Tsai, M. A. Redus, and W. R. Dowdle. 1977. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N. Engl. J. Med. 297:1197-1203.
27. Mengaud, J. M., and M. A. Horwitz. 1993. The major iron-containing protein of Legionella pneumophila is an aconitase homologous with the human iron-responsive element-binding protein. J. Bacteriol. 175:5666-5676.
28. Oldham, L. J., and F. G. Rodgers. 1985. Adhesion, penetration and intracellular replication of Legionella pneumophila: an in vitro model of pathogenesis. J. Gen. Microbiol. 131:697-706.
29. Ott, M. 1994. Genetic approaches to study Legionella pneumophila pathogenicity. FEMS Microbiol. Rev. 14:161-176.
30. Rockey, D. D., D. Grosenbach, D. E. Hruby, M. G. Peacock, R. A. Heinzen, and T. Hackstadt. 1997. Chlamydia psittaci IncA is phosphorylated by the host cell and is exposed on the cytoplasmic face of the developing inclusion. Mol. Microbiol. 24:217-228.
31. Rosenshine, I., V. Duronio, and B. B. Finlay. 1992. Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells. Infect. Immun. 60:2211-2217.
32. Rosenshine, I., S. Ruschkowski, V. Foubister, and B. B. Finlay. 1994. Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation. Infect. Immun. 62:4969-4974.
33. Rosqvist, R., K. E. Magnusson, and W. H. Wolf. 1994. Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. EMBO J. 13:964-972.
34. SAS Institute Inc. 1989. SAS/STAT user's guide, version 6, p. 943. SAS Institute, Cary, N.C.
35. Stock, J. B., A. M. Stock, and J. M. Mottonen. 1990. Signal transduction in bacteria. Nature 344:395-400.
36. Susa, M., J. Hacker, and R. Marre. 1996. De novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells. Infect. Immun. 64:1679-1684.
37. Wong, M. C., E. P. Ewing, Jr., C. S. Callaway, and W. L. Peacock, Jr. 1980. Intracellular multiplication of Legionella pneumophila in cultured human embryonic lung fibroblasts. Infect. Immun. 28:1014-1018.
38. Yamamoto, Y., T. W. Klein, H. Shinomiya, M. Nakano, and H. Friedman. 1992. Infection of macrophages with Legionella pneumophila induces phosphorylation of a 76-kilodalton protein. Infect. Immun. 60:3452-3455.
39. Zaffran, Y., J. C. Escallier, S. Ruta, C. Capo, and J. L. Mege. 1995. Zymosantriggered association of tyrosine phosphoproteins and lyn kinase with cytoskeleton in human monocytes. J. Immun. 154:3488-3497.