Chemical modification of rat hepatic microsomes with N-ethylmaleimide results in inactivation of both UDP-N-acetylglucosamine-dependent stimulation of glucuronidation and UDP-glucuronic acid uptake

Biochimica et Biophysica Acta - General Subjects

Volumn 1428, Issue 2-3, 1999, Pages 388-396

  Ikushiro, Shin Ichi ^a   Emi, Yoshikazu ^a   Kimura, Shigenobu ^a   Iyanagi, Takashi ^a  

^a UNIVERSITY OF HYOGO   (Japan)

Author keywords

Glucuronidation; N Ethylmaleimide; UDP glucuronic acid uptake; UDP glucuronosyltransferase; UDP N acetylglucosamine

Indexed keywords

4 NITROPHENOL; GLUCURONOSYLTRANSFERASE; N ETHYLMALEIMIDE; THIOL GROUP; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCURONIDATION; IN VITRO STUDY; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION ANALYSIS;

ANIMALS; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ETHYLMALEIMIDE; GLUCURONOSYLTRANSFERASE; KINETICS; MALE; MICROSOMES, LIVER; NITROPHENOLS; RATS; RATS, WISTAR; TESTOSTERONE; URIDINE DIPHOSPHATE GLUCURONIC ACID;

EID: 0032805803     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(99)00066-5     Document Type: Article

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