In vitro and in vivo antitumor activity of Yoshixol(TR) against murine L1210 leukemic cells

General Pharmacology

Volumn 33, Issue 2, 1999, Pages 179-186

  Tanaka, Satoshi ^a   Koyama, Shozo ^a   Haniu, Hisao ^a   Yamaguchi, Yoshihiro ^a   Motoyoshiya, Jiro ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

Antitumor agent; Apoptosis; L1210 cell; Leukemia; Quantum thermodynamic cell death; Vaccination; Yoshixol(TR)

Indexed keywords

4,4 DIMETHYL 6 METHYLENE 2 CYCLOHEXEN 1 ONE; ANTINEOPLASTIC AGENT; DNA FRAGMENT; LACTATE DEHYDROGENASE; TUMOR VACCINE; UNCLASSIFIED DRUG; YOSHIXOL;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GEL ELECTROPHORESIS; IN VITRO STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKEMIA L 1210; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DEATH; CELL SURVIVAL; CYCLOHEXANONES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEUKEMIA L1210; MICE; RABBITS;

EID: 0032805385     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(99)00006-3     Document Type: Article

References (36)

1. Bhattacharya C.M., Foon K.A., Kohler H. Anti-idiotype monoclonal antibodies as vaccines for human cancer. Inter Rev Immunol. 7:1991;289-302.
2. Bissonnette R.P., Echeverri F., Mahboubi A., Green D.R. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature. 359:1992;552-554.
3. Burnett A.K., Eden O.B. The treatment of acute leukaemia. Lancet. 349:1997;270-275.
4. Cohen G.M., Sun X.M., Snowden R.T., Dinsdale D., Skilleter D.N. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J. 286:1992;331-341.
5. Cotter T.G., Lennon S.V., Glynn J.G., Martin S. Cell death via apoptosis and its relationship to growth, development and differentiation of both tumor and normal cells. J Anticancer Res. 10:1990;1153-1160.
6. De Graaf T.W., Slot S.S., Peters G.J., Van Dijk W. Changes in glycosylation of L1210 cells after exposure to various antimetabolites. Eur J Cancer. 29:1993;1760-1765.
7. Dionet C., Verrelle P. Curability of mouse L1210 leukemia by combination of 5-fluorouracil, cis-diamminedichloroplatinum (II), and low doses of gamma-rays. Cancer Res. 44:1984;652-656.
8. Fisher D.E. Apoptosis in cancer therapy. crossing the threshold Cell. 78:1994;539-542.
9. Frank W., Newcomer K.L., Cirksema J., Bauer A.J., Futher B.J. Observation of the concomitant use of X rays and 5 fluorouracil in neoplasms of human. Cancer Chemother Rep. 22:1968;55-58.
10. Hernandez J.A., Land K.J., McKenna R.W. Leukemias, myeloma, and other lymphoreticular neoplasms. Cancer. 75:1995;381-394.
11. Houghton J.A., Houghton P.J., Wooten R.S. Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine, and 5-fluoro-2′-deoxyuridine. Cancer Res. 39:1979;2406-2413.
12. Kasamatsu T., Kohda K., Kawazoe Y. Cytotoxicity of antitumor agents toward cultured murine leukemia L1210 cells under a serum-deprived apoptotic condition. Anticancer Res. 15:1995;2597-2600.
13. Kataoka T., Oh-hashi F. Suppressor macrophages in tumor-bearing mice and their selective inhibition by 6-mercaptopurine. Cancer Res. 45:1985;2139-2144. a.
14. Kataoka T., Oh-hashi F. Production of antitumor T-cells in tumor-bearing mice treated with tumor vaccine and 6-mercaptopurine. Cancer Res. 45:1985;2962-2966. b.
15. Kerr J.F., Wyllie A.H., Curie A.R. Apoptosis. A basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer. 26:1972;239-257.
16. Kerr J.F. Apoptosis. Its significance in cancer and cancer therapy. Cancer. 73:1994;2013-2026.
17. Kline I., Venditti J.M., Mead J.A., Tyrer D.D., Goldin A. The antileukemic effectiveness of 5-fluorouracil and methotrexate in the combination chemotherapy of advanced leukemia L1210 in mice. Cancer Res. 26:1966;848-852. a.
18. Kline I., Venditti J.M., Tyrer D.D., Goldin A. Chemotherapy of leukemia L1210 in mice with 1-β-d-arabinofuranosylcytosine hydrochloride. I. Influence of treatment schedules. Cancer Res. 26:1966;853-859. b.
19. Koyama S., Yamaguchi Y., Tanaka S., Motoyoshiya J. A new substance (Yoshixol) with an interesting antibiotic mechanism from wood oil of Japanese traditional tree (Kiso-Hinoki), Chamaecyparis obtusa. Gen Pharmacol. 28:1997;797-804. a.
20. Koyama S., Tanaka S., Yamaguchi Y., Motoyoshya J. Apoptosis-like (possible quantum thermodynamic) cell death induced by Yoshixol and wood oil of Chamaecyparis obtusa (Kiso-Hinoki) on HeLa cell. Gen Pharmacol. 28:1997;805-811. b.
21. TR inhibits B16 melanoma cell growth in vivo and induces apoptosis-like (quantum thermodynamic) cell death. Gen Pharmacol. in press:1999.
22. Law L.W., Thelma B.D., Boyle P.J., Miller J.H. Observations on the effect of a folic-acid antagonist on transplantable lymphoid leukemias in mice. J Natl Cancer Inst. 10:1949;179-192.
23. Lowe S.W., Ruley H.E., Jacks T., Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967.
24. Lowe S.W. Cancer therapy and p53. Curr Opin Oncol. 7:1995;547-553.
25. Majno G., Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol. 146:1995;3-15.
26. Moran R.E., Straus M.J. Effects of pulse and continuous intravenous infusion of cis-diamminedichloroplatinum on L1210 leukemia in vivo. Cancer Res. 41:1981;4993-4996.
27. Nicolin A., Canti G., Marelli O., Veronese F., Goldin A. Chemotherapy and immunotherapy of L1210 leukemic mice with antigenic tumor sublines. Cancer Res. 41:1981;1358-1362.
28. Obeid L.M., Linardic C.M., Karolak L.A., Hannun Y.A. Programmed cell death induced by ceramide. Science. 259:1993;1769-1771.
29. Raychaudhuri S., Saeki Y., Chen J.J., Iribe H., Fuji H., Kohler H. Tumor-specific idiotype vaccines. II. Analysis of the tumor-related network response induced by the tumor and by internal image antigens (Ab2 beta). J Immunol. 139:1987;271-278.
30. Searle J., Kerr J.F., Bishop C.J. Necrosis and apoptosis. distinct modes of cell death with fundamentally different significance Pathol Annu. 17:1982;229-259.
31. Shi L., Nishioka W.K., Th'ng J., Bradbury E.M., Litchfield D.W., Greenberg A.H. Premature p34cdc2 activation required for apoptosis. Science. 263:1994;1143-1145.
32. Tsujimoto Y., Cossman J., Jaffe E., Croce C.M. Involvement of the bcl-2 gene in human follicular lymphoma. Science. 228:1985;1440-1443.
33. Vaux D.L., Aguila H.L., Weissman I.L. Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing. Int Immunol. 4:1992;821-824.
34. Vaux D.L. Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA. 90:1993;786-789.
35. Wyllie A.H., Kerr J.F., Curie A.R. Cell death. the significance of apoptosis Int Rev Cytol. 68:1980;251-307.
36. Wyllie A.H., Morris R.G., Smith A.L., Dunlop D. Chromatin cleavage in apoptosis. association with condensed chromatin morphology and dependence on macromolecular synthesis J Pathol. 142:1984;67-77.