Incidence and predictors of drug-induced parkinsonism in older psychiatric patients treated with very low doses of neuroleptics

Journal of Clinical Psychopharmacology

Volumn 19, Issue 4, 1999, Pages 322-328

  Caligiuri, Michael P ^a   Lacro, Jonathan P ^a,b   Jeste, Dilip V ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALOPERIDOL; NEUROLEPTIC AGENT; PERPHENAZINE; RISPERIDONE; THIORIDAZINE;

AGE; AGED; ARTICLE; COGNITION; CONTROLLED STUDY; DEMENTIA; EXTRAPYRAMIDAL SYMPTOM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; MOTOR PERFORMANCE; PARKINSONISM; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; PSYCHOSIS; SCHIZOPHRENIA; TREMOR;

AGED; ALZHEIMER DISEASE; ANTIPSYCHOTIC AGENTS; DEMENTIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INCIDENCE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEUROLOGIC EXAMINATION; PARKINSON DISEASE, SECONDARY; PROSPECTIVE STUDIES;

EID: 0032804677     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-199908000-00007     Document Type: Article

References (23)

1. Waddington JL. Mechanisms of neuroleptic-induced extrapyramidal side effects. In: Kane JM, Lieberman JA, eds. Adverse effects of psychotropic drugs. New York: The Guilford Press, 1992:246-65.
2. Ayd F. A survey of drug-induced extrapyramidal reactions. JAMA 1961;175:1054-60.
3. McCreadie RG, Robertson LJ, Wiles DH. The Nithsdale schizophrenia surveys. IX: akathisia, parkinsonism, tardive dyskinesia and plasma neuroleptic levels. Br J Psychiatry 1992;161:739-99.
4. Rajput AH. Drug-induced parkinsonism in the elderly. Geriatr Med Today 1984;3:99-107.
5. Hoffman WF, Labs SM, Casey DE. Neuroleptic-induced parkinsonism in older schizophrenics. Biol Psychiatry 1987;22:427-39.
6. Jeste DV, Naimark D. Medication-induced movement disorders. In: Tasman A, Lieberman J, Kay J, eds. Psychiatry. Philadelphia: W.B. Saunders Co., 1997:1304-54.
7. Sweet RA, Pollock BG, Rosen J, Mulsant BH, Altieri LP, Perel JM. Early detection of neuroleptic-induced parkinsonism in elderly patients with dementia. J Geriatr Psychiatry Neurol 1994;7:251-3.
8. Caligiuri MP, Lohr JB. Instrumental motor predictors of neuroleptic-induced parkinsonism in newly medicated schizophrenia patients. J Neuropsychiatry Clin Neurosci 1997;9:562-7.
9. Caligiuri MP, Rockwell E, Jeste DV. Extrapyramidal side effects in patients with Alzheimer's disease treated with low-dose neuroleptic medication. Am J Geriatr Psychiatry 1998;6:75-82.
10. Chakos MH, Mayerhoff DI, Loebel AD, Alvir JMA, Lieberman JA. Incidence and correlates of acute extrapyramidal syndromes in first episode of schizophrenia. Psychopharmacol Bull 1992;28: 81-6.
11. Caligiuri MP, Lohr JB, Jeste DV. Parkinsonism in neurolepticnaive schizophrenia patients. Am J Psychiatry 1993;150:1343-8.
12. Caligiuri MP, Lohr JB Panton, D, Harris MJ. Motor abnormalities associated with late-life psychosis. Schizophr Bull 1993;19:747-54.
13. Sweet RA, Akil M, Mulsant BH, Ulrich R, Paternak RE, Zubenko GS. Determinants of spontaneous extrapyramidal symptoms in elderly psychiatric inpatients diagnosed with Alzheimer's disease, major depressive disorder, or psychotic disorders. J Neuropsychiatry Clin Neurosci 1998;10:68-77.
14. Simpson G, Angus JWS. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand Suppl 1970;212:11-9.
15. Sweet RA, DeSensi EG, Zubenko GS. Reliability and applicability of movement disorder rating scales in the elderly. J Neuropsychiatry Clin Neurosci 1993;5:56-60.
16. Caligiuri MP, Lohr JB, Bracha HS, Jeste, DV. Clinical and instrumental assessment of neuroleptic induced parkinsonism in patients with tardive dyskinesia. Biol Psychiatry 1990;29:139-48.
17. Caligiuri MP. Portable device for quantifying parkinsonian rigidity. Mov Disord 1994;9:57-63.
18. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-98.
19. Overall JE, Gorham DR. The Brief Psychiatric Rating Scale (BPRS): recent developments in ascertainment and scaling. Psychopharmacol Bull 1988;24:97-9.
20. Saltz BL, Woemer MG, Kane JM, Lieberman JA, Alvir JMJ, Bergmann KJ, Blank K, Koblenzer J, Kahaner K. Prospective study of tardive dyskinesia incidence in the elderly. JAMA 1991;266:2402-6.
21. Sweet RA, Mulsant BH, Pollack BG, Rosen J, Altieri LP. Neuroleptic-induced parkinsonism in elderly patients diagnosed with psychotic major depression and dementia of the Alzheimer type. Am J Geriatr Psychiatry 1996;4:311-9.
22. Chatterjee A, Chakos M, Koreen A, Geisler S, Sheitmen B, Woerner M, Kane JM, Alvir J, Lieberman JA. Prevalence and clinical correlates of extrapyramidal signs and spontaneous dyskinesia in never-medicated schizophrenic patients. Am J Psychiatry 1995;152:1724-9.
23. Amt J, Skarsfeldt T. Do novel antipsychotics have similar pharmacologic characteristics? A review of the evidence. Neuropsychopharmacology 1998;18:63-101.