A single carbocyclic nucleotide substitution in a 12mer DNA gives a Hoogsteen basepaired duplex (till 38°C) and a hairpin (till 65°C). A 600 MHz NMR spectroscopic study

Nucleosides and Nucleotides

Volumn 18, Issue 6-7, 1999, Pages 1593-1596

  Isaksson, J ^a   Maltseva, T ^a   Agback, P ^a   Luo, X ^a   Kumar, A ^a   Zamaratski, E ^a   Chattopadhyaya, J ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC NUCLEOSIDE; DOUBLE STRANDED DNA; NUCLEOSIDE ANALOG; NUCLEOTIDE;

BASE PAIRING; CHEMICAL MODIFICATION; CONFERENCE PAPER; DNA STRUCTURE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ANALYSIS; TEMPERATURE;

EID: 0032804599     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319908044793     Document Type: Conference Paper

References (4)

1. (a) Thibaudeau, C.; Plavec. J.; Chattopadhyaya, J. J. Org. Chem., 1998, 63, 4967,
2. (b) Thibaudeau, C.; Kumar, .A.; Bekiroglu, S.; Matsuda, A.; Marquez, V. E.; Chattopadhyaya, J. J. Org. Chem., 1998, 63, 5447. See all stereoelectronic effect related references in the reference section of these two papers.
3. Denisov, A.; Bekiroglu, S.; Maltseva, T.; Sandström, A.; Altmann, K.-H.; Egli, M.; Chattopadhyaya, J. J. Biomol. Str. Dyna., 1998 submitted, and references therein.
4. Portmann, S; Altmann, K.-H.; Reynes, N.; Egli, M. J. Am. Chem. Soc., 1997, 119, 2396.