Hypothalamo-limbic involvement in modulation of tooth-pump stimulation evoked nociceptive response in rats

Indian Journal of Physiology and Pharmacology

Volumn 43, Issue 3, 1999, Pages 323-331

  Sinha, Ramanjan ^a   Sharma, Ratna ^a   Mathur, Rashmi ^a   Nayar, Usha ^b  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b ARABIAN GULF UNIVERSITY   (Bahrain)

Author keywords

Amygdala; Antinociception; Hippocampus; Hypothalamus; Jaw opening reflex; Tooth pulp

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; HYPOTHALAMUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; JAW OPENING REFLEX; LIMBIC SYSTEM; MALE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; RAT;

AMYGDALA; ANIMALS; DENTAL PULP; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; HIPPOCAMPUS; HYPOTHALAMIC AREA, LATERAL; HYPOTHALAMUS; LIMBIC SYSTEM; MALE; NOCICEPTORS; PAIN MEASUREMENT; RATS; RATS, WISTAR; REFLEX; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 0032804506     PISSN: 00195499     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Baklavadzhyan OG, Dabinyan AG, Taturyan I, Ipekchyan NM. Neuronal and neurochemical mechanisms of hypothalamic inhibition of the nociceptive reflex. Fiziol Ahu 1987; 73(9) : 1160-1169.
2. Carstens E, Fraunhoffer M, Sueberg M. Inhibition of spinal dorsal horn neuronal responses to noxious skin heating by LH stimulation in the cat. J Neurophysiol 1983; 59(1): 192-204.
3. Tasker RR, Choinere M, Libman SM, Melzack R. Analgesia produced by injection of lidocaine into the lateral hypothalamus. Pain 1987; 31 : 237-249.
4. Carstens E. Inhibition of spinal dorsal born neuron responses to noxious skin heating by LH stimulation in the cat. J Neurophysiol 1982; 48(3) : 808-822.
5. Kachaturian H, Lewis ME, Watson SJ. Enkephalin systems in diencephalon and brain stem of the cat. J Comp Neurol 1983; 220(3) : 310-320.
6. Kowada K, Kawarada K, Matsumoto N. Conditioning stimulation of the central amygdaloid nucleus inhibits the jaw opening reflex in the cat. Jap J Physiol 1992; 42 : 443-458.
7. Mena Narasaiah B, Mathur R, Nayar U. Amygdalar involvement in Pain. Indian J Physiol Pharmacol 1995; 39(4) : 339-346.
8. Zimmermann A. Ethical quidelines for investigations of experimental pain in conscious animals. Pain 1983; 16:109-110.
9. Toda K, Iriki A, Ichioka M. Selective stimulation of intrapulpal nerve of rat lower incisor using a bipolar electrode method. Physiol Behav 1981; 26: 307-311.
10. Tanaka H, Toda K. Inhibition of the tooth pulp evoked jaw opening reflex by stimulation of raphe nuclei in the rat. Experimental Neurology 1982; 77:102-112.
11. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. Academic press, Sydney, 1982.
12. Mason P, Strassman A, Macoewocz R. Is the jaw-opening reflex a valid model of pain? Brain Res Rev 1985; 10: 137-146.
13. Curtis AL, Marwah J. The nociceptive jaw opening reflex : evidence for alpha adrenoceptor involvement. Pharmaco Biochem Behav 1987; 26 : 437-444.
14. Anderson DJ, Hannam AG, Matthews B. Sensory mechanisms in mammalian teeth and their supporting structures. Physiol Rev 1970; 50 : 171-195.
15. Matthews B. Functions of tooth pulp afferents. Adv Pain Res Ther 1979; 3 : 261-263.
16. Sessle BJ, Greenwood LF. Input to trigeminal brain stem neurons from facial, oral, tooth pulp and pharyngolaryngeal tissues. 1. Responses to innocuous and noxious stimuli. Brain Res 1976; 117:211-226.
17. Albe-fessard D, Nashold B, Pollin B, Woda A, Thalamic and midbrain responses to dental pulp afferent messages in awake cat. J Physiol (Paris) 1971; 73 : 347-357.
18. Hannam AG. The effect of repetitive stimulation on the jaw-opening reflex in the cat. Arch Oral Biol 1973; 18: 155-163.
19. Oliveras JL, Woda A, Guilbaud G, Besson JM. Inhibition of the jaw opening reflex by electrical stimulation of the periaqueductal gray matter in the awake, unrestrained cat. Brain Research 1974; 72:328-331.
20. Aimone LD, Bauer CA, Gebhart GF. Brain stem relays mediating stimulation produced antinociception from lateral hypothalamus in rat. Neurosci 1988; 8(7) : 2652-2663.
21. Lopez R, Young SL, Cox VC. Analgesia for formalin induced pain by lateral hypothalamic stimulation. Brain Res 1991; 563 : 1-6.
22. Oleson TD, Kirkpatrick, Goodman. Elevation of pain threshold to tooth shock by brain stimulation in primates. Brain Res 1980; 194 : 79-95.
23. Dafny N, Dong WQ, Prieto-Gomex C, ReylesVazques C, Standord J, Qiao JT. Lateral hypothalamus : site involved in pain modulation. Neurosci 1996; 70 : 449-460.
24. Oomura Y. Input-output organization in the hypothalamus relating to food intake behaviour. In : morgane PJ, Panksepp J, eds. Handbook of the Hyporthalamus, New York, Marcel Dekker, 1980: 557-620.
25. Klamt JG, Prado WA, Antinociception and behavioural changes induced by carbachol microinjected into indentified sites of the rat brain. Brain Res 1991; 549 : 9-18.
26. Al-Rodhan N, Chippkin R, Yaksh TL. The antinociceptive effects of SCH-32615m a neutral endopeptidase (enkephalinase) inhibitor. microinjected into the periaqueductal, ventral medulla and amygdala. Brain Res 1990; 520 : 123-130.
27. Rodgers RJ. Elevation of aggressive threshold in rats by intraamygdaloid injection of morphine sulphate. Pharmacol Biochem Beha 1977; 6 : 385-390.
28. Baklavadzhyan OG, Khimonidi RK. Lededev VP, Skobelev VA, Sakukhanyan RV. Investigation of pathways of transmission of hypothalamic sympatho-activating effects to the spinal cord, Neirofiziologia 1982; 14(3) : 307-314.
29. Morrell JG, Grenberger LM, Pfaff DW. Hypothalamic, other diencephalic and telencephalic neurons that project to the dorsal midbrain. J Comp Neurol 1981; 201(4) : 589-620.
30. Pert A, Yakash T. Sites of morphine-induced analgesia in the primate brain : relation to pain pathways. Brain Res 1974; 80(1) : 135-140.