A phase II study of a three-drug combination (cisplatin, ifosfamide and vinorelbine) plus granulocyte-colony stimulating factor in advanced non small cell lung cancer

Journal of Chemotherapy

Volumn 11, Issue 4, 1999, Pages 306-309

  Tognoni, Alessandra ^a   Cadenotti, L ^a   Pensa, F ^a   Vaira, F ^a   Vigani, A ^a   Bancalari, L ^a   Cordani, S ^a   Maggiani, R ^a   Canessa, P A ^a   Pronzato, P ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cisplatin; Dose intensity; Filgrastim; Ifosfamide; Lung cancer; Mesna; Non small cell lung cancer (NSCLC); Vinorelbine

Indexed keywords

CISPLATIN; IFOSFAMIDE; MESNA; NAVELBINE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; AGED; ANEMIA; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG ACTIVITY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HISTOPATHOLOGY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG NON SMALL CELL CANCER; MALE; MUCOSA INFLAMMATION; NAUSEA; NEUROPATHY; NEUTROPENIA; PHASE 2 CLINICAL TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; THROMBOCYTOPENIA; VOMITING;

EID: 0032803130     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.1999.11.4.306     Document Type: Article

References (7)

1. Non-Small-Cell Lung Cancer Collaborative Group. Chemotherapy in Non-Small-Cell Lung Cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials. Br Med J 1995; 311: 899-909.
2. Souquet PJ, Cahuvin F, Boissel JP, et al. Polychemotherapy in advanced non small cell lung cancer: a meta-analysis. Lancet 1993; 342: 19-24.
3. Crino L, Clerici M, Figoli F, et al. Chemotherapy of advanced Non-Small-Cell Lung Cancer: a comparison of three active regimens. A randomized trial of the Italian Oncology Group for Clinical Research (GOIRC). Ann Oncol 1995; 6; 347-353.
4. Le Chevalier T, Brisgand D, Douillard J-Y, et al. Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of a European multicenter trial including 612 patients. J Clin Oncol 1994; 12: 360-366.
5. De Carli A, La Vecchia C. Cancer mortality in Italy 1991. Tumori 1994; 80: 405-415.
6. Pronzato P, Bertelli GG, Vigani A, et al. A feasibility study of accelerated chemotherapy with cisplatin, epidoxorubicin and cyclophosphamide (PEC) in advanced ovarian cancer. Br J Cancer 1993; 73: 1425-1427.
7. Gabrilove J, Jakubowsji A, Scher H, et al. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium. N Engl J Med 1988; 318: 1414-1422.