Multiple mechanisms for polyunsaturated fatty acid regulation of hepatic gene transcription

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 60, Issue 5-6, 1999, Pages 345-349

  Jump, D B ^a   Thelen, A ^a   Ren, B ^a   Mater, M ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; PROSTANOID;

ADIPOCYTE; ANIMAL CELL; CELL CULTURE; CELL STRAIN 3T3; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID OXIDATION; GENE INDUCTION; GENETIC TRANSCRIPTION; LIPID METABOLISM; LIPOGENESIS; MICROSOME; MOUSE; NONHUMAN; PEROXISOME; PLEIOTROPY; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALIA; EUKARYOTA;

EID: 0032802481     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(99)80010-6     Document Type: Conference Paper

References (19)

1. 1. Jump D. B., Clarke S. D., Thelen A., Liimatta M., Ren B., Badin M. Dietary PUFA regulation of gene transcription. Prog Lipid Res 1996; 35: 227-241.
2. 2. Clarke S. D., Jump D. B. Dietary PUFA regulation of gene transcription. Annu Rev Nutr 1994; 14: 83-98.
3. 3. Jump D. B., Clarke S. D., MacDougald O. A., Thelen A. PUFA inhibit S14 gene transcription in rat liver and cultured hepatocytes. Proc Natl Acad Sci USA 1993; 90: 8454-8458.
4. 4. Jump D. B., Clarke S. D., Thelen A., Liimatta M. Coordinate regulation of glycolytic and lipogenic gene expression by PUFA. J Lipid Res 1994; 35: 1076-1084.
5. 5. Landchultz K., Jump D. B., MacDougald O. A., Lane M. D. Transcriptional control of stearoyl-CoA desaturase-1 by PUFA. Biochem Biophys Res Comm 1994; 200: 763-768.
6. 6. Liimatta M., Towle H. C., Clarke S. D., Jump D. B. Dietary PUFA interfere with the insulin/carbohydrate activation of L-pyruvate kinase gene transcription. Molecular Endocrinology 1994; 8: 1147-1153.
7. 7. Jump D. B., Ren B., Clarke S. D., Thelen A. Effects of fatty acids on hepatic gene expression. Prostaglandins Leukot Essen Fatty Acids 1994; 52: 107-111.
8. 8. Mater M. K., Pan D. Bergen W. G., Jump D. B. Arachidonic acid inhibits lipogenic gene expression in 3T3-L1 adipocytes through a prostanoid pathway. J Lipid Res 1998; 39: 1327-1334.
9. 9. Ren B., Thelen A., Jump D. B. Peroxisome proliferator-activated receptor α inhibits hepatic S14 gene transcription. J Biol Chem 1996; 271: 17167-17173.
10. 10. Ren B., Thelen A., Peters J. M., Gonzalez F., Jump D. B. PUFA suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor α. J Biol Chem 1997; 272: 26827-26832.
11. 11. Jump D. B., Badin M. V., Thelen A. The CCAAT-box binding factor, NF-Y, is required for thyroid hormone regulation of rat liver S14 gene transcription. J Biol Chem 1997; 272: 27778-27786.
12. 12. Goodnight S. H., Harris W. S., Connor W. E., Illingworth D. R. Polyunsaturated fatty acids, hyperlipidemia and thrombosis. Artheriosclerosis 1982; 2: 87-113.
13. 13. Phillipson B. E., Rothrock D. W., Connor W. E., Harris W. S., Illingworth D. R. Reduction of plasma lipids, lipoproteins and apolipoproteins by dietary fish oils in patients with hypertriglyceridemia. N Engl J Med 1985; 312: 1210-1216.
14. 14. Thomassen M. S., Christiansen E. N., Norum K. R. Characterization of the stimulatory effect of high-fat diets on peroxisomal β-oxidation in rat liver. Biochem J 1982; 206: 195-201.
15. 15. Aarsland A., Lundquist M., Borretsen B., Berge R. K. On the effect of peroxisomal β-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rat. Lipids 1990; 25: 546-551.
16. 16. Brown S. B., Maloney M., Kinlaw W. B. 'Spot 14' protein function at the pretranslational level in the regulation of hepatic metabolism by thyroid hormone and glucose. J Biol Chem 1997; 272: 2163-2166.
17. 17. Lee S. S. T., Pineau T., Drago J. et al. Targeted disruption of the α isoform of the peroxisome proliferator activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 1995; 15: 3012-3022.
18. 18. Forman B. M., Chen J., Evans R. M. Hypolipidemic drugs, PUFA and eicosanoids are ligands for PPARα and δ. Proc Natl Acad Sci USA 1997; 94: 4312-4317.
19. 19. Smith W. W. Prostanoid biosynthesis and mechanism of action. Am J Physiol 1992; 263: F181-F191.